Rhythms ofDrosophila periodgene expression in culture

The Genetics and Biology of Drosophila

1978 • 3,910 citations

The development of Drosophila melanogaster

1994 • 3,057 citations

Clock Mutants of Drosophila melanogaster

1971 • 2,191 citations

Suprachiasmatic nucleus : the mind's clock

1991 • 1,730 citations

Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms

1995 • 1,437 citations

Feedback of the Drosophila period gene product on circadian cycling of its messenger RNA levels

1990 • 1,103 citations

Circadian Rhythms in Cultured Mammalian Retina

1996 • 710 citations

Loss of Circadian Behavioral Rhythms and per RNA Oscillations in the Drosophila Mutant timeless

1994 • 627 citations

Staging the metamorphosis of Drosophila melanogaster

1981 • 530 citations

Circadian rhythm of firing rate recorded from single cells in the rat suprachiasmatic brain slice

1982 • 511 citations

A light-entrainment mechanism for the Drosophila circadian clock

1996 • 471 citations

Light-Induced Degradation of TIMELESS and Entrainment of the Drosophila Circadian Clock

1996 • 462 citations

Biological clocks in seasonal reproductive cycles

1981 • 449 citations

Temporal phosphorylation of the Drosophila period protein.

1994 • 410 citations

Circadian fluctuations of period protein immunoreactivity in the CNS and the visual system of Drosophila

1990 • 404 citations

Regulation of the Drosophila Protein Timeless Suggests a Mechanism for Resetting the Circadian Clock by Light

1996 • 400 citations

Antibodies to the period gene product of drosophila reveal diverse tissue distribution and rhythmic changes in the visual system

1988 • 396 citations

Rhythmic Expression of timeless : A Basis for Promoting Circadian Cycles in period Gene Autoregulation

1995 • 368 citations

Isolation of timeless by PER Protein Interaction: Defective Interaction Between timeless Protein and Long-Period Mutant PER ^L

1995 • 364 citations

Expression of the period clock gene within different cell types in the brain of Drosophila adults and mosaic analysis of these cells' influence on circadian behavioral rhythms

1992 • 326 citations

Regulation of Nuclear Entry of the Drosophila Clock Proteins Period and Timeless

1996 • 322 citations

Circadian clock functions localized in xenopus retinal photoreceptors

1993 • 307 citations

ISOLATION OF CIRCADIAN CLOCK MUTANTS OF NEUROSPORA CRASSA

1973 • 277 citations

Temporally regulated nuclear entry of the Drosophila period protein contributes to the circadian clock

1995 • 275 citations

Resetting the Drosophila Clock by Photic Regulation of PER and a PER-TIM Complex

1996 • 272 citations

Circadian Rhythm of Optic Nerve Impulses Recorded in Darkness from Isolated Eye of Aplysia

1969 • 264 citations

The suprachiasmatic nuclei contain a tetrodotoxin-resistant circadian pacemaker.

1987 • 262 citations

Positional Cloning and Sequence Analysis of the Drosophila Clock Gene, timeless

1995 • 262 citations

A promoterless period gene mediates behavioral rhythmicity and cyclical per expression in a restricted subset of the drosophila nervous system

1994 • 258 citations

A circadian oscillator in cultured cells of chicken pineal gland

1979 • 253 citations

Trippings along the trail to the molecular mechanisms of biological clocks

1995 • 242 citations

Product of per locus of Drosophila shares homology with proteoglycans

1986 • 241 citations

A family of unusually spliced biologically active transcripts encoded by a Drosophila clock gene

1987 • 235 citations

Changes in abundance or structure of the per gene product can alter periodicity of the Drosophila clock

1987 • 227 citations

Hormonal control of rates of metamorphic development in the tobacco hornworm Manduca sexta

1983 • 224 citations

Constitutive overexpression of the Drosophila period protein inhibits period mRNA cycling.

1994 • 223 citations

Circadian clock locus frequency: protein encoded by a single open reading frame defines period length and temperature compensation.

1994 • 221 citations

Circadian oscillations in period gene mRNA levels are transcriptionally regulated.

1992 • 212 citations

Circadian Rhythm in Membrane Conductance Expressed in Isolated Neurons

1993 • 208 citations

Sex-Specific Assembly of a Dosage Compensation Complex on the Nematode X Chromosome

1996 • 186 citations

Novel Features of Drosophila period Transcription Revealed by Real-Time Luciferase Reporting

1996 • 175 citations

Behavior of period-altered circadian rhythm mutants ofDrosophila in light: Dark cycles (Diptera: Drosophilidae)

1992 • 169 citations

Molecular mapping of point mutations in the period gene that stop or speed up biological clocks in Drosophila melanogaster.

1987 • 157 citations

Spatial and temporal expression of the period gene in Drosophila melanogaster.

1988 • 157 citations

Ecdysteroids regulate the release and action of eclosion hormone in the tobacco hornworm, Manduca sexta (L.)

1983 • 150 citations

Genetic alteration of nerve membrane excitability in temperature-sensitive paralytic mutants of Drosophila melanogaster

1980 • 146 citations

Photoendocrine transduction in cultured chick pineal cells: effect of light, dark, and potassium on the melatonin rhythm

1988 • 138 citations

Expression of ion channels and mutational effects in giant Drosophila neurons differentiated from cell division-arrested embryonic neuroblasts

1991 • 137 citations

Marker proteins for gene expression

1995 • 120 citations

Circadian clock in cell culture: I. Oscillation of melatonin release from dissociated chick pineal cells in flow-through microcarrier culture

1988 • 117 citations

Localization of a Circadian Pacemaker in the Eye of a Mollusc, Bulla

1982 • 100 citations

Circadian Systems, V. The Driving Oscillation and the Temporal Sequence of Development

1970 • 85 citations

Prothoracic glands of the saturniid moth Samia cynthia ricini possess a circadian clock controlling gut purge timing

1982 • 76 citations

Architecture and physiology of insect cerebral neurosecretory cells

1984 • 66 citations

Patterns of E74A RNA and protein expression at the onset of metamorphosis in Drosophila

1991 • 59 citations

Circadian regulation of synthesis of ecdysteroids by prothoracic glands of the insect Rhodnius prolixus: Evidence of a dual oscillator system

1991 • 57 citations

The ionic mechanism of action potentials in neurosecretory cells and non-neurosecretory cells of the silkworm

1980 • 50 citations

Circadian control of a daily rhythm in hemolymph ecdysteroid titer in the insect Rhodnius prolixus (Hemiptera)

1985 • 49 citations

Photoperiodic regulation of insect and molluscan hormones.

1984 • 49 citations

Saxitoxin binding to sodium channels in head extracts from wild-type and tetrodotoxin-sensitive strains of Drosophila melanogaster

1980 • 43 citations

The molecular basis of the Neurospora clock

1995 • 42 citations

Further Evaluation of the Tetrodotoxin-Resistant Circadian Pacemaker in the Suprachiasmatic Nuclei

1991 • 38 citations

Individual pineal cells exhibit a circadian rhythm in melatonin secretion

1993 • 28 citations

In vitro photosensitivity of ecdysteroid synthesis by prothoracic glands of Rhodnius prolixus (Hemiptera)

1992 • 26 citations

The multiple roles of per in the Drosophila circadian clock

1995 • 26 citations

Circadian modulation of ecdysteroid titer in Galleria mellonella larvae

1989 • 24 citations

Genetic dissection of the circadian clock: A timeless story

1995 • 22 citations

An ultrastructural analysis of the ecdysoneless ((l(3)ecd 1ts) ring gland during the third larval instar of Drosophila melanogaster

1991 • 16 citations