Decreased expression of heat shock protein 70 mRNA and protein after heat treatment in cells of aged rats.

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Genomic sequencing.

1984 • 8,343 citations

THE HEAT-SHOCK PROTEINS

1988 • 5,214 citations

THE HEAT-SHOCK RESPONSE

1986 • 4,580 citations

Speculations on the functions of the major heat shock and glucose-regulated proteins

1986 • 1,574 citations

Replicative life-span of cultivated human cells. Effects of donor's age, tissue, and genotype.

1970 • 1,002 citations

Protooncogene induction and reprogramming of cardiac gene expression produced by pressure overload.

1988 • 877 citations

RNA splicing is interrupted by heat shock and is rescued by heat shock protein synthesis

1986 • 524 citations

Thermolability of ubiquitin-activating enzyme from the mammalian cell cycle mutant ts85

1984 • 522 citations

Hyperthermia Protects Against Light Damage in the Rat Retina

1988 • 445 citations

Posttranscriptional regulation of hsp70 expression in human cells: effects of heat shock, inhibition of protein synthesis, and adenovirus infection on translation and mRNA stability.

1987 • 248 citations

Heat shock proteins in thermotolerance and other cellular processes.

1987 • 220 citations

Two transcriptional activators, CCAAT-box-binding transcription factor and heat shock transcription factor, interact with a human hsp70 gene promoter.

1987 • 173 citations

Mitogen and lymphokine stimulation of heat shock proteins in T lymphocytes.

1988 • 168 citations

Attenuated induction of heat shock gene expression in aging diploid fibroblasts

1989 • 167 citations

Inactive Enzyme Molecules in Aging Mice: Liver Aldolase

1973 • 131 citations

Induction of B2 RNA polymerase III transcription by heat shock: enrichment for heat shock induced sequences in rodent cells by hybridization subtraction

1986 • 131 citations

Heat shock protein in mammalian brain and other organs after a physiologically relevant increase in body temperature induced by D-lysergic acid diethylamide.

1983 • 98 citations

Age-related changes of heat shock protein gene transcription in human peripheral blood mononuclear cells

1988 • 89 citations

Induction of heat shock protein transcripts and B2 transcripts by various stresses in Chinese hamster cells

1989 • 84 citations

Synthesis of heat shock proteins in rat liver after ischemia and hyperthermia

1985 • 81 citations

Posttranscriptional Regulation of hsp70 Expression in Human Cells: Effects of Heat Shock, Inhibition of Protein Synthesis, and Adenovirus Infection on Translation and mRNA Stability

1987 • 77 citations

In vitro senescence of Syrian hamster mesenchymal cells of fetal to aged adult origin. Inverse relationship between in vivo donor age and in vitro proliferative capacity

1986 • 60 citations

Control of hsp70 RNA levels in human lymphocytes.

1987 • 46 citations

Mutations that induce the heat shock response of Drosophila

1987 • 43 citations

Two Transcriptional Activators, CCAAT-Box-Binding Transcription Factor and Heat Shock Transcription Factor, Interact with a Human hsp7O Gene Promoter

1987 • 36 citations

Body Temperature Responses of Aged Mice to Ambient Temperature and Humidity Stress

1984 • 30 citations