Transverse alternating field electrophoresis and applications to mammalian genome mapping

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1984 • 4,899 citations

CpG-rich islands and the function of DNA methylation

1986 • 3,760 citations

Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis

1984 • 2,847 citations

Separation of Large DNA Molecules by Contour-Clamped Homogeneous Electric Fields

1986 • 1,525 citations

Cloning of Large Segments of Exogenous DNA into Yeast by Means of Artificial Chromosome Vectors

1987 • 1,517 citations

Electrophoretic Separations of Large DNA Molecules by Periodic Inversion of the Electric Field

1986 • 920 citations

The Mosaic Genome of Warm-Blooded Vertebrates

1985 • 887 citations

Separation of chromosomal DNA molecules from yeast by orthogonal-field-alternation gel electrophoresis

1984 • 887 citations

A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA

1985 • 668 citations

Enzymatic Synthesis of Deoxyribonucleic Acid

1962 • 466 citations

A Physical Map of the Escherichia coli K12 Genome

1987 • 409 citations

Antigenic variation in trypanosoma brucei analyzed by electrophoretic separation of chromosome-sized DNA molecules

1984 • 368 citations

Quinacrine, A Chromosome Stain Specific for Deoxyadenylate-Deoxythymidylate-Rich Regions in DNA

1972 • 302 citations

Fractionation of large mammalian DNA restriction fragments using vertical pulsed-field gradient gel electrophoresis

1986 • 290 citations

A large inverted duplication allows homologous recombination between chromosomes heterozygous for the proximal t complex inversion

1987 • 230 citations

Size variation in chromosomes from independent cultured isolates of Plasmodium falciparum

1985 • 201 citations

Mapping of the class II region of the human major histocompatibility complex by pulsed-field gel electrophoresis

1986 • 184 citations

Molecular analysis of the Duchenne muscular dystrophy region using pulsed field gel electrophoresis

1987 • 171 citations

Quantum yield of acridines interacting with DNA of defined base sequence

1972 • 160 citations

Pulsed field gel electrophoresis: a technique for fractionating large DNA molecules

1986 • 149 citations

Asymmetrical distribution of CpG in an ‘average’ mammalian gene

1982 • 140 citations

Stable Amplified DNA in Drug-Resistant Leishmania Exists as Extrachromosomal Circles

1986 • 124 citations

Construction of a mini-chromosome by deletion and its mitotic and meiotic behaviour in fission yeast

1986 • 116 citations

A Novel Instrument for Separating Large DNA Molecules with Pulsed Homogeneous Electric Fields

1988 • 110 citations

Variability of DNA methylation patterns during serial passage of human diploid fibroblasts

1982 • 97 citations

Separation of chromosomal DNA molecules fromC.albicansby pulsed field gel electropboresis

1986 • 97 citations

The effect of site-specific methylation on restriction-modification enzymes

1987 • 95 citations

Partial physical map of human chromosome 21

1988 • 87 citations

Regional localization of DNA sequences on chromosome 21 using somatic cell hybrids.

1986 • 82 citations

Man-made Objects on the Surface of the Central North Pacific Ocean

1973 • 79 citations

Mapping of the gene encoding the beta-amyloid precursor protein and its relationship to the Down syndrome region of chromosome 21.

1988 • 74 citations

Synthesis of decadeoxyribonucleotides containing N⁶-methyladenine, N⁴-methylcytosine, and 5-methylcytosine: recognition and cleavage by restriction endonucleases (nucleosides and nucleotides part 74)¹

1987 • 66 citations

A calculation of fragment lengths obtainable from human DNA with 78 restriction enzymes: an aid for cloning and mapping

1986 • 47 citations

Construction of long-range restriction maps in human DNA using pulsed field gel electrophoresis

1987 • 45 citations

Mapping using gene encyclopaedias

1987 • 44 citations

Abstracts of workshop presentations (Part 13 of 13)

1985 • 26 citations

Separation of large DNA molecules by modified pulsed field gradient gel electrophoresis

1986 • 26 citations

The persistence of chromosomes in somatic cell hybrids correlates with the enzymatic hypermethylation of their dna

1981 • 9 citations