Evidence that a variety of cultured cells secrete protease nexin and produce a distinct cytoplasmic serine protease‐binding factor

The Reliability of Molecular Weight Determinations by Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis

1969 • 20,498 citations

Plasminogen: Purification from Human Plasma by Affinity Chromatography

1970 • 2,160 citations

Protease-nexin: A cellular component that links thrombin and plasminogen activator and mediates their binding to cells

1980 • 424 citations

Detection of an unusually stable fibrinolytic inhibitor produced by bovine endothelial cells.

1983 • 400 citations

AN ENZYMATIC FUNCTION ASSOCIATED WITH TRANSFORMATION OF FIBROBLASTS BY ONCOGENIC VIRUSES

1973 • 368 citations

Cultured bovine endothelial cells produce both urokinase and tissue-type plasminogen activators.

1982 • 362 citations

A proenzyme form of human urokinase.

1982 • 350 citations

Control of proliferation of human vascular endothelial cells. Characterization of the response of human umbilical vein endothelial cells to fibroblast growth factor, epidermal growth factor, and thrombin

1978 • 312 citations

Macrophage fibrinolytic activity: Identification of two pathways of plasmin formation by intact cells and of a plasminogen activator inhibitor

1982 • 225 citations

Molecular species of plasminogen activators secreted by normal and neoplastic human cells.

1980 • 202 citations

Released protease-nexin regulates cellular binding, internalization, and degradation of serine proteases.

1981 • 155 citations

The dexamethasone-induced inhibitor of fibrinolytic activity in hepatoma cells. A cellular product which specifically inhibits plasminogen activation.

1982 • 95 citations

Purification of human protease nexin.

1983 • 93 citations

Effects of nicotine on cultured rat heart cells

1970 • 91 citations

Cells regulate their mitogenic response to thrombin through release of protease nexin

1982 • 82 citations

Phorbol ester and mitogens stimulate human fibroblast secretions of plasmin-activatable plasminogen activator and protease nexin, an antiactivator/antiplasmin.

1983 • 78 citations

Plasminogen activator from cells transformed by an oncogenic virus. Inhibitors of the activation reaction

1979 • 72 citations

Regulation of extracellular plasminogen activator by human fibroblasts. The role of protease nexin.

1983 • 65 citations

Dexamethasone regulation of plasminogen activator in embryonic and tumor-derived human cells.

1980 • 54 citations

Internalization and degradation of thrombin and up regulation of thrombin-binding sites in corneal endothelial cells.

1981 • 51 citations

Epidermal growth factor carrier protein binds to cells via a complex with released carried protein nexin.

1982 • 49 citations

Extracellular matrix synthesis by skeletal muscle in culture. Proteins and effect of enzyme degradation.

1982 • 48 citations

Concomitant secretion by transformed SVWI38-VA13-2RA cells of plasminogen activator(s) and substance(s) which prevent their detection

1978 • 43 citations

Thrombin‐mediated mitogenesis: The role of secreted protease nexin

1982 • 32 citations

Two proteinase inhibitors associated with peritoneal macrophages.

1983 • 19 citations

Dexamethasone inhibition and phorbol myristate acetate stimulation of plasminogen activator in human embryonic lung cells

1981 • 17 citations

Detection and partial characterization of a protein in mouse fibroblasts that binds and inhibits trypsin.

1980 • 14 citations

An electrophoretic assay for plasminogen activator

1979 • 8 citations

INTERACTIONS OF SERINE PROTEASES WITH HUMAN FIBROBLASTS: REGULATION BY PROTEASE-NEXIN, A CELLULAR COMPONENT WITH SIMILARITIES TO ANTITHROMBIN III

1981 • 5 citations