Hyperresponsivity to the Serotonin Agonist m-Chlorophenylpiperazine in Alzheimer's Disease

Clinical diagnosis of Alzheimer's disease

1984 • 27,279 citations

The Brief Psychiatric Rating Scale

1962 • 10,683 citations

A New Clinical Scale for the Staging of Dementia

1982 • 6,699 citations

Alzheimer's Disease and Senile Dementia: Loss of Neurons in the Basal Forebrain

1982 • 3,563 citations

Quantification of Sleepiness: A New Approach

1973 • 2,454 citations

Selective reminding for analysis of memory and learning

1973 • 1,039 citations

Reduced somatostatin-like immunoreactivity in cerebral cortex from cases of Alzheimer disease and Alzheimer senile dementa

1980 • 866 citations

Monoamine Metabolites in CSF and Suicidal Behavior

1981 • 692 citations

Loss of neurons of origin of the adrenergic projection to cerebral cortex (nucleus locus ceruleus) in senile dementia

1982 • 677 citations

Serotonin function in anxiety

1987 • 467 citations

Biochemical Assessment of Serotonergic and Cholinergic Dysfunction and Cerebral Atrophy in Alzheimer's Disease

1983 • 440 citations

Serotonergic Responsivity in Obsessive-Compulsive Disorder

1987 • 378 citations

Nucleus raphe dorsalis in Alzheimer's disease: Neurofibrillary tangles and loss of large neurons

1985 • 332 citations

Serotonergic Responsivity in Obsessive-Compulsive Disorder

1988 • 299 citations

Anticholinergic Sensitivity in Patients With Dementia of the Alzheimer Type and Age-Matched Controls

1987 • 295 citations

Attenuation of the euphoriant and activating effects of d- and l-amphetamine by lithium carbonate treatment

1975 • 237 citations

Neuroendocrine evidence for serotonin receptor hypersensitivity in panic disorder

1988 • 225 citations

Cholinergic terminals in rat hippocampus possess 5-HT1B receptors mediating inhibition of acetylcholine release

1986 • 220 citations

Presynaptic Serotonergic Dysfunction in Patients with Alzheimer's Disease

1987 • 213 citations

Serotonin Receptor Changes in Dementia of the Alzheimer Type

1984 • 194 citations

Memory failures in progressive idiopathic dementia.

1981 • 189 citations

Neuroendocrine Effects ofM-Chlorophenylpiperazine, a Serotonin Agonist, in Humans

1985 • 181 citations

Biochemical Evidence of Selective Nerve Cell Changes in the Normal Ageing Human and Rat Brain

1983 • 145 citations

Serotonin Function and Mechanism of Action of Antidepressant Treatment

1984 • 143 citations

Further studies of the putative serotonin agonist, m-chlorophenylpiperazine: Evidence for a serotonin receptor mediated mechanism of action in humans

1986 • 142 citations

Induction of migrainelike headaches by the serotonin agonist m-chlorophenylpiperazine

1988 • 134 citations

Evidence for a role of brain serotonergic neurotransmission in avoidance learning.

1985 • 110 citations

Binding of the Novel Serotonin Agonist 8‐Hydroxy‐2‐(Di‐n‐Propylamino) Tetralin in Normal and Alzheimer Brain

1986 • 105 citations

The alteration of serotonin binding sites in aged human brain

1978 • 92 citations

Effect of 5-Hydroxytryptophan on Serum Cortisol Levels in Major Affective Disorders

1984 • 90 citations

Evidence of the modulatory role of serotonin in acetylcholine release from striatal interneurons

1981 • 87 citations

L‐Tryptophan and prolactin release: Evidence for interaction between 5‐HT₁ and 5‐HT₂ receptors

1986 • 82 citations

The effect of lithium on 5-HT-mediated neuroendocrine responses and platelet 5-HT receptors

1986 • 75 citations

Effects of ageing on cardiac performance and coronary flow in spontaneously hypertensive and normotensive rats

1985 • 69 citations

Circadian Temperature Variation in Healthy Aged and in Alzheimer's Disease

1984 • 69 citations

Effects of m-chlorophenylpiperazine on receptor binding and brain metabolism of monoamines in rats

1981 • 59 citations

Enhancement of the memory of a previously learned aversive habit following pre-test administration of a variety of serotonergic antagonists in mice

1986 • 57 citations

High-dose naloxone affects task performance in normal subjects

1983 • 52 citations

TFMPP may produce its stimulus effects via a 5-HT1B mechanism

1986 • 49 citations

5-Hydroxytryptamine-like properties of m-chlorophenylpiperazine: comparison with quipazine

1980 • 47 citations

Central serotoninmimetic action of phenylpiperazines.

1980 • 42 citations

Hyperthermia induced by m-CPP in the rat and its modification by antidepressant treatments

1989 • 38 citations

Alaproclate: A pharmacokinetic and biochemical study in patients with dementia of Alzheimer type

1983 • 37 citations

The acute effect of p-chloroamphetamine on the retention of fear conditioning in the rat: Evidence for a role of serotonin in memory consolidation

1981 • 26 citations

Neuromolecular Modulation of Experimentally-Induced Retrograde Amnesia

1973 • 25 citations

A preliminary study of the effects of intravenous m-chlorophenylpiperazine, a serotonin agonist, in elderly subjects

1989 • 25 citations

Dicyclomine- and pirenzepine-sensitive muscarinic receptors mediate inhibition of [3H]serotonin release in different rat brain areas

1986 • 22 citations

Fenfluramine-induced suppression of food intake and locomotor activity is differentially altered by the selective type A monoamine oxidase inhibitor clorgyline

1988 • 20 citations

A new postsynaptic serotonin receptor agonist suitable for studies in humans.

1985 • 18 citations

Clorgyline treatment differentially affects m-chlorophenylpiperazine-induced neuroendocrine changes

1988 • 15 citations

M-chlorophenylpiperazine increases blood pressure and heart rate in pithed and conscious rats

1987 • 12 citations