Systemic and regional vascular effects of atrial natriuretic peptide in a rat model of chronic heart failure

Statistical principles in experimental design.

1962 • 27,228 citations

Statistical Principles in Experimental Design

1964 • 8,376 citations

A rapid and potent natriuretic response to intravenous injection of atrial myocardial extract in rats

1981 • 3,128 citations

Decreased Catecholamine Sensitivity and β-Adrenergic-Receptor Density in Failing Human Hearts

1982 • 2,259 citations

Blood flow measurements with radionuclide-labeled particles

1977 • 2,072 citations

Atrial natriuretic factor—a circulating hormone stimulated by volume loading

1985 • 1,250 citations

The amino acid sequence of an atrial peptide with potent diuretic and natriuretic properties

1983 • 743 citations

Bioactive Cardiac Substances: Potent Vasorelaxant Activity in Mammalian Atria

1983 • 711 citations

Atrial natriuretic factor in normal subjects and heart failure patients. Plasma levels and renal, hormonal, and hemodynamic responses to peptide infusion.

1986 • 711 citations

Atriopeptin: A Cardiac Hormone Intimately Involved in Fluid, Electrolyte, and Blood-Pressure Homeostasis

1986 • 491 citations

Vasodilator Therapy of Cardiac Failure

1977 • 487 citations

Experimental myocardial infarction in the rat: qualitative and quantitative changes during pathologic evolution.

1978 • 460 citations

Alterations in vasomotor tone in congestive heart failure

1982 • 369 citations

Decreased Lymphocyte Beta-Adrenergic-Receptor Density in Patients with Heart Failure and Tolerance to the Beta-Adrenergic Agonist Pirbuterol

1981 • 331 citations

Plasma levels of immunoreactive atrial natriuretic factor in healthy subjects and in patients with edema.

1985 • 324 citations

Ser-Leu-Arg-Arg-Atriopeptin III: The Major Circulating Form of Atrial Peptide

1985 • 310 citations

Atrial natriuretic factor inhibits angiotensin-, norepinephrine-, and potassium-induced vascular contractility.

1984 • 294 citations

Physiologic regulation of atrial natriuretic peptide receptors in rat renal glomeruli.

1985 • 224 citations

George E. Brown memorial lecture. Role of atrial peptides in body fluid homeostasis.

1986 • 221 citations

Studies of the Circulation with Radioactive Microspheres

1969 • 217 citations

Failure of atriopeptin II to cause arterial vasodilation in the conscious rat.

1985 • 192 citations

Effect of a purified atrial natriuretic factor on rat and rabbit vascular strips and vascular beds

1984 • 190 citations

Renal and systemic hemodynamic effects of synthetic atrial natriuretic peptide in the anesthetized rat.

1986 • 186 citations

Ca-dependent hemodynamic and natriuretic effects of atrial extract in isolated rat kidney

1984 • 182 citations

Experimental myocardial infarction in the rat.

1959 • 170 citations

Long-Term Preservation of Ischemic Myocardium after Experimental Coronary Artery Occlusion

1978 • 167 citations

HAEMODYNAMIC EFFECTS OF ATRIAL PEPTIDE INFUSION IN HEART FAILURE

1986 • 157 citations

Renal, Hemodynamic, and Hormonal Responses to Atrial Natriuretic Peptide Infusions in Normal Man, and Effect of Sodium Intake*

1986 • 144 citations

The right auricle of the heart is an endocrine organ

1983 • 138 citations

Compensatory hypertrophy in the heart after myocardial infarction in the rat

1983 • 136 citations

An atrial peptide is a potent renal vasodilator substance.

1984 • 127 citations

Vascular receptor binding activities and cyclic GMP responses by synthetic human and rat atrial natriuretic peptides (ANP) and receptor down-regulation by ANP

1985 • 112 citations

The auricular myocardiocytes of the heart constitute an endocrine organ characterization of a porcine cardiac peptide hormone, cardiodilatin-126

1984 • 112 citations

Multiple simultaneous determinations of hemodynamics and flow distribution in conscious rat

1984 • 112 citations

Effects of synthetic atrial natriuretic peptide on renal function and renin release in acute experimental heart failure.

1985 • 112 citations

Effect of atrial natriuretic factor on blood pressure, renin, and aldosterone in Goldblatt hypertension.

1985 • 100 citations

Decreased density of binding sites for atrial natriuretic peptide on platelets of patients with severe congestive heart failure

1988 • 91 citations

Cardiovascular effects of atrial natriuretic factor in anesthetized and conscious dogs.

1986 • 88 citations

Comparative vascular pharmacology of the atriopeptins.

1985 • 86 citations

Atrial natriuretic peptide in chronic heart failure in the rat: a correlation with ventricular dysfunction.

1986 • 82 citations

Atriopeptins: renal-specific vasodilators in conscious dogs

1985 • 81 citations

Atriopeptin II lowers cardiac output in conscious sheep

1985 • 73 citations

Coronary Vasoconstrictor Effects of Atriopeptin II

1985 • 61 citations

Atrial natriuretic peptide decreases circulatory capacitance in areflexic rats.

1986 • 57 citations

Atrial natriuretic factor selectively increases renal blood flow in conscious spontaneously hypertensive rats

1984 • 56 citations

Changes of regional blood flow induced by atrial natriuretic factor (ANF) in conscious rats

1985 • 55 citations

Differing hemodynamic responses to atrial natriuretic factor in two models of hypertension

1986 • 55 citations

Der natriuretische Vorhoffaktor bei schwerer kongestiver Herzinsuffizienz: Plasmaspiegel, hämodynamische, hormonale und renale Effekte^*

2008 • 43 citations

Atrial extract: hemodynamics in Wistar-Kyoto and spontaneously hypertensive rats

1985 • 40 citations

Effects of diltiazem on cardiac function and regional blood flow at rest and during exercise in a conscious rat preparation of chronic heart failure (myocardial infarction).

1985 • 39 citations

Receptor-independent sequestration of beta-adrenergic ligands by alveolar type II cells

1986 • 34 citations

Mechanism of action of vasoconstrictor responses to atriopeptin II in conscious SHR

1985 • 31 citations

Regional vascular adjustments during recovery from myocardial infarction in rats

1986 • 29 citations

Mechanism of action of nitroglycerin during exercise in a rat model of heart failure. Improvement of blood flow to the renal, splanchnic, and cutaneous beds.

1981 • 25 citations

Comparative effects of intracoronary vasodilators on restoring coronary perfusion during flow-reducing coronary stenosis in the dog

1987 • 20 citations

Hemodynamic effects of synthetic atrial natriuretic factor (ANF) in dogs with acute left ventricular failure

1985 • 19 citations