Estrogen Content and Metabolism in Human Breast Tumor Tissues and Cells

Increased 2-Hydroxylation of Estradiol as a Possible Mechanism for the Anti-Estrogenic Effect of Cigarette Smoking

1986 • 665 citations

Abnormal oxidative metabolism of estradiol in women with breast cancer.

1982 • 256 citations

Aromatase, 17β-hydroxysteroid dehydrogenase and intratissular sex hormone concentrations in cancerous and normal glandular breast tissue in postmenopausal women

1986 • 249 citations

Antiestrogen action of 2-hydroxyestrone on MCF-7 human breast cancer cells.

1984 • 248 citations

Estradiol 16 alpha-hydroxylation in the mouse correlates with mammary tumor incidence and presence of murine mammary tumor virus: a possible model for the hormonal etiology of breast cancer in humans.

1985 • 210 citations

THE RELATIONSHIP BETWEEN 17β‐HYDROXYSTEROID DEHYDROGENASE ACTIVITY AND OESTROGEN CONCENTRATIONS IN HUMAN BREAST TUMOURS AND IN NORMAL BREAST TISSUE

1983 • 188 citations

Recent data on estrogen sulfatases and sulfotransferases activities in human breast cancer

1992 • 103 citations

Estrogen sulfatase and estrogen sulfotransferase in human primary mammary carcinoma

1983 • 99 citations

The Effects of Cimetidine on the Oxidative Metabolism of Estradiol

1989 • 81 citations

Plasma estrone-sulfate assessment of reduced estrogen production during treatment of metastatic breast carcinoma

1982 • 75 citations

Oestrogen receptors and metabolism of oestrone sulphate in human mammary carcinoma

1980 • 74 citations

Predictability of Response to Endocrine Ablation in Advanced Breast Carcinoma

1973 • 73 citations

Plasma estrone sulfate levels in postmenopausal women

1980 • 69 citations

Omega-3 Fatty Acids: Modulation of Estrogen Metabolism and Potential for Breast Cancer Prevention

1988 • 69 citations

Computer-aided mobile phase optimization and chromatogram simulation in high-performance liquid chromatography

1985 • 56 citations

A correlation between estrogen sulfotransferase levels and estrogen receptor status in human primary breast carcinoma.

1979 • 53 citations

Interaction of histones with estrogens. Covalent adduct formation with 16.alpha.-hydroxyestrone

1985 • 50 citations

Metabolic fate of estradiol in human mammary cancer cells in culture: estrogen sulfate formation and cooperativity exhibited by estrogen sulfotransferase

1988 • 47 citations

STUDIES ON THE PATTERN OF CIRCULATING STEROIDS IN THE NORMAL MENSTRUAL CYCLE

1976 • 44 citations

Solvent optimization of reversed-phase high-performance liquid chromatography for polar adrenal steroids using computer-predicted retentions

1984 • 42 citations

Pediatric Peripheral Neuroectodermal Tumors, Oncogenes, and Differentiation

1990 • 38 citations

Uptake and Concentration of Steroid Hormones in Mammary Tissues

1986 • 37 citations

Different conversion metabolic rates of testosterone are associated to hormone-sensitive status and -response of human prostate cancer cells

1994 • 34 citations

Simple approach to measure metabolic pathways of steroids in living cells

1991 • 30 citations

Relationship between estrogen receptors, 17β-hydroxysteroid dehydrogenase and estrogen content in human breast cancer

1979 • 30 citations

STUDIES ON THE PATTERN OF CIRCULATING STEROIDS IN THE NORMAL MENSTRUAL CYCLE

1977 • 29 citations

A relationship between estrogen sulfurylation and estrogen and progesterone receptor status in human mammary carcinoma.

1980 • 23 citations

Estrone conversion rates by human endometrial cancer cell lines

1986 • 22 citations

Synergistic interaction of growth factors and albumin in regulating estradiol synthesis in breast cancer cells

1992 • 20 citations

Cytosol Albumin Content in Operable Breast Cancer Correlations to Steroid Hormone Receptors, Other Prognostic Factors and Prognosis

1991 • 19 citations

Metabolism and Biologic Response of Estrogen Sulfates in Hormone‐Dependent and Hormone‐Independent Mammary Cancer Cell Lines. Effect of Antiestrogens

1990 • 17 citations

Measurement of steroidogenesis in rodent Leydig cells: a comparison between pregnenolone and testosterone production

1989 • 16 citations

Regulation of estrogen sulfotransferase by estrogen in MCF-7 human mammary cancer cells

1992 • 15 citations

Steroid Profiles and Optimization of High‐Performance Liquid Chromatographic Analytic Procedure^a

1986 • 14 citations

Extracellular proteins in breast tumor cytosol.

1987 • 13 citations

Metabolism of 17β‐Estradiol and the Adrenal‐Derived Estrogen 5‐Androstene‐3β, 17β‐Diol (Hermaphrodiol) in Human Mammary Cell Lines^a

1990 • 12 citations

Steroids in Normal and Neoplastic Breast Tissues

1990 • 11 citations

Oxidative and reductive pathways of estrogens in hormone responsive and non-responsive human breast cancer cells in vitro

1995 • 10 citations

Effect of serum albumin on estrogen metabolism in human cancer cell lines

1995 • 10 citations

The Origin of Oestrone Sulphate in Normal and Malignant Breast Tissues in Postmenopausal Women

1992 • 10 citations

17β-Hydroxysteroid dehydrogenase activity in endometrial cancer cells: Different metabolic pathways of estradiol in hormone-responsive and non-responsive intact cells

1995 • 9 citations

Mammary steroidogenesis: Therapeutic implications

1987 • 8 citations

Reconsidering Some of the Biosynthetic Pathways Leading to Formation of C₁₉‐Steroids

1990 • 5 citations

Enzymic synthesis of steroid sulfate by mammary cancer and its clinical implications.

1971 • 4 citations

Hormones and the fetus, volume 1

1986 • 1 citations