Functional Characterization of Structural Alterations in the Sequence of the Vasodilatory Peptide Maxadilan Yields a Pituitary Adenylate Cyclase-activating Peptide Type 1 Receptor-specific Antagonist

Prediction of the Secondary Structure of Proteins from their Amino Acid Sequence

1979 • 2,930 citations

Isolation of a novel 38 residue-hypothalamic polypeptide which stimulates adenylate cyclase in pituitary cells

1989 • 1,810 citations

Functional expression and tissue distribution of a novel receptor for vasoactive intestinal polypeptide

1992 • 752 citations

Synthesis of a model protein of defined secondary and quaternary structure. Effect of chain length on the stabilization and formation of two-stranded alpha-helical coiled-coils.

1984 • 559 citations

Molecular cloning and functional expression of the pituitary adenylate cyclase-activating polypeptide type I receptor.

1993 • 379 citations

Cloning and functional characterization of a third pituitary adenylate cyclase-activating polypeptide receptor subtype expressed in insulin-secreting cells.

1994 • 248 citations

Isolation of maxadilan, a potent vasodilatory peptide from the salivary glands of the sand fly Lutzomyia longipalpis

1991 • 203 citations

Maxadilan, the Vasodilator from Sand Flies, Is a Specific Pituitary Adenylate Cyclase Activating Peptide Type I Receptor Agonist

1997 • 199 citations

A Novel Vasodilatory Peptide from the Salivary Glands of the Sand Fly Lutzomyia longipalpis

1989 • 90 citations

Solution structure of pituitary adenylate cyclase activating polypeptide by nuclear magnetic resonance spectroscopy

1993 • 84 citations

Structural requirements for the binding of the pituitary adenylate‐cyclase‐activating peptide to receptors and adenylate‐cyclase activation in pancreatic and neuronal membranes

1991 • 60 citations

Antagonistic properties are shifted back to agonistic properties by further N‐terminal shortening of pituitary adenylate‐cyclase‐activating peptides in human neuroblastoma NB‐OK‐1 cell membranes

1992 • 55 citations

Structure-activity study of hCGRP8-37, a calcitonin gene-related peptide receptor antagonist

1992 • 43 citations

Maxadilan Binds to Membrane Fractions of Brain Tissue

1995 • 16 citations

Structural Characterization and Location of Disulphide Linkages of a Potent Vasodilatory Peptide, Recombinant Maxadilan, by a Multiple Mass Spectrometric Approach

1996 • 8 citations