Isolation of cDNA clones coding for rat isovaleryl-CoA dehydrogenase and assignment of the gene to human chromosome 15

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1984 • 4,899 citations

Supercoil Sequencing: A Fast and Simple Method for Sequencing Plasmid DNA

1985 • 2,505 citations

Localization of single copy DNA sequences on G-banded human chromosomes by in situ hybridization

1981 • 836 citations

Isovaleric acidemia: a new genetic defect of leucine metabolism.

1966 • 348 citations

Purification and characterization of short-chain, medium-chain, and long-chain acyl-CoA dehydrogenases from rat liver mitochondria. Isolation of the holo- and apoenzymes and conversion of the apoenzyme to the holoenzyme.

1985 • 217 citations

Separation and properties of five distinct acyl-CoA dehydrogenases from rat liver mitochondria. Identification of a new 2-methyl branched chain acyl-CoA dehydrogenase.

1983 • 171 citations

The Isolation and Identification of N-Isovalerylglycine from Urine of Patients with Isovaleric Acidemia

1967 • 165 citations

Purification of low-abundance messenger RNAs from rat liver by polysome immunoadsorption.

1982 • 119 citations

Purification and characterization of isovaleryl coenzyme A dehydrogenase from rat liver mitochondria.

1983 • 117 citations

Purification and characterization of 2-methyl-branched chain acyl coenzyme A dehydrogenase, an enzyme involved in the isoleucine and valine metabolism, from rat liver mitochondria.

1983 • 109 citations

Genes for synapsin I, a neuronal phosphoprotein, map to conserved regions of human and murine X chromosomes.

1986 • 90 citations

Cloning and screening with nanogram amounts of immunopurified mRNAs: cDNA cloning and chromosomal mapping of cystathionine beta-synthase and the beta subunit of propionyl-CoA carboxylase.

1986 • 74 citations

Molecular cloning and nucleotide sequence of cDNA encoding the entire precursor of rat liver medium chain acyl coenzyme A dehydrogenase.

1987 • 73 citations

Molecular cloning of cDNAs encoding rat and human medium-chain acyl-CoA dehydrogenase and assignment of the gene to human chromosome 1.

1986 • 72 citations

Biosynthesis of four rat liver mitochondrial acyl-CoA dehydrogenases: In vitro synthesis, import into mitochondria, and processing of their precursors in a cell-free system and in cultured cells

1987 • 57 citations

Hybridoma technology in the biosciences and medicine

1986 • 55 citations

Coding sequence of the precursor of the beta subunit of rat propionyl-CoA carboxylase.

1986 • 54 citations

Mechanism of action of short-chain, medium-chain, and long-chain acyl-CoA dehydrogenases. Direct evidence for carbanion formation as an intermediate step using enzyme-catalyzed C-2 proton/deuteron exchange in the absence of C-3 exchange.

1985 • 54 citations

The ornithine transcarbamylase leader peptide directs mitochondrial import through both its midportion structure and net positive charge.

1987 • 44 citations

A metalloprotease involved in the processing of mitochondrial precursor proteins

1986 • 40 citations

An essential cysteine residue located in the vicinity of the FAD-binding site in short-chain, medium-chain, and long-chain acyl-CoA dehydrogenases from rat liver mitochondria.

1985 • 33 citations

Regional assignment of genes for mannose phosphate isomerase, pyruvate kinase-3, and <i>β</i><sub>2 </sub>microglobulin expression on human chromosome 15 by hybridization of cells from a t(15;22) (q14;q13.3) translocation carrier

1978 • 24 citations

Isovaleric acidemia: A new genetic defect of leucine metabolism

1966 • 24 citations

Purification of Low-Abundance Messenger RNAs by Polysome Isolation with Polyclonal Antibodies

1985 • 1 citations

Deleted Work

1955 • 0 citations