The Toxicity of Repeated Exposures to Rolipram, a Type IV Phosphodiesterase Inhibitor, in Rats

Phosphodiesterase inhibitors: new opportunities for the treatment of asthma.

1991 • 383 citations

New Drugs Annual—Cardiovascular Drugs

1984 • 222 citations

Prevention of autoimmune demyelination in non-human primates by a cAMP-specific phosphodiesterase inhibitor.

1995 • 178 citations

Results of a Phase II Study of the Antidepressant Effect of Rolipram

1984 • 175 citations

Characteristic behavioral alterations in rats induced by rolipram and other selective adenosine cyclic 3?,5?-monophosphate phosphodiesterase inhibitors

1982 • 138 citations

Structure-activity relationships for inhibitors of phosphodiesterase from erythrocytes and other tissues.

1972 • 61 citations

Cardiotoxicity of a new inotrope/vasodilator drug (SK&F 94120) in the dog

1986 • 36 citations

Subchronic toxicity of orally administered (gavage and dosed-feed) theophylline in fischer 344 rats and B6C3F1 mice*1

1988 • 35 citations

CARDIOVASCULAR LESIONS IN SPRAGUE‐DAWLEY RATS INDUCED BY LONG‐TERM TREATMENT WITH CAFFEINE

1981 • 32 citations

Role of dopaminergic and adrenergic receptors in the pathogenesis of arterial lesions induced by fenoldopam mesylate and dopamine in the rat.

1989 • 32 citations

Pathologic changes in blood vessels following administration of an inotropic vasodilator (ICI 153, 110) to the rat

1990 • 29 citations

Multiple molecular forms of phosphodiesterase: an overview.

1986 • 27 citations

The Influence of Rolipram on the Central Serotoninergic System

1981 • 21 citations

Acute and subchronic toxicology of LY-195115 in rats and dogs

1987 • 19 citations

Long-Term Effects of an Inotropic Phosphodiesterase Inhibitor (ICI 153,110) on the Rat Salivary Gland, Harderian Gland, and Intestinal Mucosa

1991 • 16 citations

Acute, subchronic, and chronic toxicity of the cardiotonic isomazole in rats*1

1989 • 10 citations

Cardiovascular and adrenal proliferative lesions in Fischer 344 rats induced by long-term treatment with type III phosphodiesterase inhibitors (postive inotropic agents), isomazole and indolidan

1991 • 8 citations

Coronary Artery Toxicity in Beagle Dogs Given Indolidan, a Type III Phosphodiesterase Inhibitor

1993 • 8 citations

Deleted Work

1955 • 0 citations