Effects of age on levels of cysteine, glutathione and related enzyme activities in livers of mice and rats and an attempt to replenish hepatic glutathione level of mouse with cysteine derivatives

A spectrophotometric method for the direct determination of cysteine in the presence of other naturally occurring amino acids

1967 • 1,157 citations

A scheme for the colorimetric determination of microgram amounts of thiols

1958 • 754 citations

The Regulation of Hepatic Glutathione

1985 • 615 citations

Development of Mammalian Sulfur Metabolism: Absence of Cystathionase in Human Fetal Tissues

1972 • 312 citations

Glutathione contents of tissues in the aging mouse

1980 • 268 citations

Effect of glutathione depletion on tissue deposition of methylmercury in rats

1975 • 211 citations

Role of glutathione in prevention of acetaminophen-induced hepatotoxicity by N-acetyl-L-cysteine in vivo: studies with N-acetyl-D-cysteine in mice.

1986 • 200 citations

Stimulation of hepatic glutathione formation by administration of L-2-oxothiazolidine-4-carboxylate, a 5-oxo-L-prolinase substrate.

1981 • 199 citations

Effect of chronic food restriction in aging rats II. Liver cytosolic antioxidants and related enzymes

1989 • 127 citations

Anti-oxidant defences and peroxidation in liver and brain of aged rats

1990 • 124 citations

Effects of cysteine pro-drugs on acetaminophen-induced hepatotoxicity.

1986 • 76 citations

Fasting-induced depletion of glutathione in the aging mouse

1993 • 63 citations

On the chemistry and biochemistry of 3-mercaptopyruvic acid, the alpha-keto acid analog of cysteine.

1982 • 57 citations

Glutathione levels in hepatic and extrahepatic tissues of mice as a function of age

1980 • 54 citations

Reactions of pyrzdoxal 5'-phosphate, 6-aminocaproic acid, cysteine, and penicilamine. Models for reactions of Schiff base linkages in pyridoxal 5'-phosphate-requiring enymes.

1975 • 48 citations

The effect of cysteine and N-acetyl cysteine on rat liver glutathione (GSH)

1983 • 40 citations

Thiazolidine derivatives as source of free l-cysteine in rat tissue

1993 • 32 citations

Diquat-Induced Oxidative Damage in BCNU-Pretreated Hepatocytes of Mature and Old Rats

1993 • 30 citations

Determination of Glutathione and Glutathione Disulfide in Biological Samples Using Acrylonitrile as a Thiol-Blocking Reagent

1996 • 29 citations

Changes in glutathione and glutathione metabolizing enzymes in erythrocytes and lymphocytes of mice as a function of age

1984 • 29 citations

Age‐Dependent changes in rat liver lipid peroxidation and glutathione content induced by acute ethanol ingestion

1987 • 27 citations

Changes in levels of glutathione and related compounds and activities of glutathione-related enzymes during rat liver regeneration

1995 • 26 citations

Effect of aging on metabolic zonation in rat liver: Acinar distribution of GSH metabolism

1992 • 20 citations

Age-associated enhancement of diquat-induced lipid peroxidation and cytotoxicity in isolated rat hepatocytes.

1992 • 18 citations

Sensitive determination of cystathionine and assays for cystathionine β- and γ-lyase, as well as cystathionine β-synthase, using high-performance liquid chromatography

1992 • 17 citations

Toxicity evaluations of l-cysteine and Procysteine™, a cysteine prodrug, given once intravenously to neonatal rats

1993 • 17 citations

Hepatoprotective effects of cystathionine against acetaminophen-induced necrosis.

1989 • 16 citations

Effects of Age on Rat Glutathione Metabolism

1991 • 12 citations

Age dependence of rat liver function measurements

1989 • 8 citations

高速液体クロマトグラフィーによるシスタチオニンの高感度定量およびシスタチオニンβ-およびγ-リアーゼならびにシスタチオニンβ-シンターゼの分析法

1992 • 8 citations

A Simple and Specific Colorimetric Determination of Cysteine with p-Dimethylaminocinnamaldehyde

1983 • 2 citations