Protein Anatomy: C-Tail Region of Human Tau Protein as a Crucial Structural Element in Alzheimer's Paired Helical Filament Formation in Vitro
Data up to Jan 2025
Total Citations Per Year
Abstract
References (17)
Molecular cloning: A laboratory manual
1990 • 85,659 citations
Solid Phase Peptide Synthesis. I. The Synthesis of a Tetrapeptide
1963 • 7,266 citations
The distribution of tau in the mammalian central nervous system.
1985 • 1,518 citations
Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain.
1989 • 989 citations
Expression of separate isoforms of human tau protein: correlation with the tau pattern in brain and effects on tubulin polymerization.
1990 • 849 citations
Cell Biology of the Amyloid beta-Protein Precursor and the Mechanism of Alzheimer's Disease
1994 • 749 citations
Alzheimer-like paired helical filaments and antiparallel dimers formed from microtubule-associated protein tau in vitro.
1992 • 463 citations
MAP2 and tau segregate into dendritic and axonal domains after the elaboration of morphologically distinct neurites: an immunocytochemical study of cultured rat cerebrum
1987 • 363 citations
A new siliconized‐glass fiber as support for protein‐chemical analysis of electroblotted proteins.
1988 • 319 citations
Brain Levels of Microtubule‐Associated Protein τ Are Elevated in Alzheimer's Disease: A Radioimmuno‐Slot‐Blot Assay for Nanograms of the Protein
1992 • 289 citations
Subunit structure of paired helical filaments in Alzheimer's disease.
1985 • 224 citations
Molecular biology of transmissible spongiform encephalopathies
1996 • 171 citations
The microtubule binding repeats of tau protein assemble into filaments like those found in Alzheimer's disease
1992 • 167 citations
Assembly of Alzheimer‐like filaments from full‐length tau protein
1994 • 154 citations
Identification of 3- and 4-repeat tau isoforms within the PHF in Alzheimer's disease.
1991 • 143 citations
Structural stability of paired helical filaments requires microtubule-binding domains of Tau: A model for self-association
1991 • 131 citations
Protein anatomy: functional roles of barnase module.
1993 • 48 citations