The cDNA structure and expression analysis of the genes for the cysteine proteinase inhibitor cystatin C and for β₂‐microglobulin in rat brain

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

[2] New M13 vectors for cloning

1983 • 5,402 citations

DNA sequence analysis with a modified bacteriophage T7 DNA polymerase.

1987 • 2,266 citations

Inducible expression of H–2 and Ia antigens on brain cells

1984 • 656 citations

Isolation of six cysteine proteinase inhibitors from human urine. Their physicochemical and enzyme kinetic properties and concentrations in biological fluids.

1986 • 499 citations

Use of synthetic oligonucleotides as hybridization probes: isolation of cloned cDNA sequences for human beta 2-microglobulin.

1981 • 423 citations

The plasma proteins : structure, function, and genetic control

1975 • 388 citations

Protein size and cerebrospinal fluid composition

1974 • 386 citations

The Physiology and Pathophysiology of the Cerebrospinal Fluid

1988 • 386 citations

Human gamma-trace, a basic microprotein: amino acid sequence and presence in the adenohypophysis.

1982 • 329 citations

Physiology and Pathophysiology of the Cerebrospinal Fluid

1987 • 317 citations

Transthyretin

1986 • 311 citations

The cystatins: a new class of peptidase inhibitors

1987 • 293 citations

Structure of wild-type and mutant mouse β2-microglobulin genes

1982 • 230 citations

Identification of the probable inhibitory reactive sites of the cysteine proteinase inhibitors human cystatin C and chicken cystatin.

1987 • 212 citations

Rat transthyretin (prealbumin). Molecular cloning, nucleotide sequence, and gene expression in liver and brain.

1985 • 200 citations

High prealbumin and transferrin mRNA levels in the choroid plexus of rat brain

1985 • 190 citations

Molecular cloning and sequence analysis of cDNA coding for the precursor of the human cysteine proteinase inhibitor cystatin C

1987 • 183 citations

Thyroxine transport in choroid plexus.

1987 • 177 citations

Rat choroid plexus specializes in the synthesis and the secretion of transthyretin (prealbumin). Regulation of transthyretin synthesis in choroid plexus is independent from that in liver.

1986 • 167 citations

Distribution of transferrin synthesis in brain and other tissues in the rat.

1987 • 144 citations

Protein Inhibitors of Cysteine Proteinases. III. Amino-Acid Sequence of Cystatin from Chicken Egg White

1983 • 127 citations

Localization of human prealbumin in choroid plexus epithelium.

1983 • 125 citations

Rat ceruloplasmin. Molecular cloning and gene expression in liver, choroid plexus, yolk sac, placenta, and testis.

1987 • 121 citations

Structure and expression of the rat transthyretin (prealbumin) gene.

1988 • 105 citations

The Choroid Plexus in Health and Disease

2013 • 100 citations

Synthesis, Processing, and Secretion of Plasma Proteins by the Liver and Other Organs and Their Regulation

1987 • 83 citations

Synthesis of transthyretin (pre-albumin) mRNA in choroid plexus epithelial cells, localized by in situ hybridization in rat brain.

1986 • 80 citations

Synthesis of plasma proteins in fetal, adult, and neoplastic human brain tissue

1986 • 80 citations

Cysteine proteinases and their inhibitors

1988 • 78 citations

Multiple mRNA species with distinct 3′ termini are transcribed from the β2-microglobulin gene

1983 • 75 citations

Convection of Cerebral Interstitial Fluid and Its Role in Brain Volume Regulation

1986 • 72 citations

Amino acid sequence of rat liver thiol proteinase inhibitor

1983 • 71 citations

High levels of messenger RNA for transthyretin (prealbumin) in human choroid plexus

1986 • 70 citations

Protein filtration and secretion at human body fluid barriers

1980 • 70 citations

Hereditary Cerebral Amyloid Angiopathy: The amyloid fibrils contain a protein which is a variant of Cystatin C, an inhibitor of lysosomal cysteine proteases

1986 • 68 citations

Amino acid sequence of rat epidermal thiol proteinase inhibitor

1984 • 67 citations

Transferrin gene expression in choroid plexus of the adult rat brain

1987 • 67 citations

Protein Synthesis in Single Cell Suspensions from Rat Liver

1972 • 60 citations

The disulphide bridges of human cystatin C (γ‐trace) and chicken cystatin

1984 • 55 citations

Localization of immunoreactive transthyretin (prealbumin) and of transthyretin mRNA in fetal and adult rat brain

1986 • 52 citations

The blood-brain barrier redefined

1986 • 38 citations

Two rat homologues of human cystatin C

1988 • 34 citations

Ultrastructural Characteristics of Adult Choroid Plexus: Relation to the Blood–Cerebrospinal Fluid Barrier to Proteins

1975 • 32 citations

The fate of plasma protein which escapes from blood vessels of the choroid plexus of the rat–an electron microscope study

1981 • 30 citations

Synthesis of Albumin via a Precursor Protein in Cell Suspensions from Rat Liver

1976 • 29 citations

The Expression of α(1)-Acid Glycoprotein mRNA during Rat Development

1989 • 29 citations

Expression of mouse beta 2-microglobulin in frozen and formaldehyde-fixed central nervous tissues: comparison of tissue behind the blood-brain barrier and tissue in a barrier-free region.

1986 • 24 citations

Synthesis of rat apolipoprotein E by escherichia coli infected with recombinant bacteriophage

1984 • 19 citations

Correlation between protein data in normal lumbar CSF and morphological findings of choroid plexus epithelium: a biochemical corroboration of barrier transport via tight junction pores

1986 • 18 citations

Cystatin S and the related cysteine proteinase inhibitors in human saliva

1986 • 16 citations

Biosynthesis of albumin via a precursor protein in Morris hepatoma 5123tc.

1976 • 8 citations