Point Mutations in awd Which Revert the Prune/Killer of Prune Lethal Interaction Affect Conserved Residues That Are Involved in Nucleoside Diphosphate Kinase Substrate Binding and Catalysis

[6] Use of T7 RNA polymerase to direct expression of cloned genes

1990 • 6,681 citations

The P-loop — a common motif in ATP- and GTP-binding proteins

1990 • 2,029 citations

Evidence for a Novel Gene Associated With Low Tumor Metastatic Potential

1988 • 1,304 citations

2 Evolutionary and Structural Relationships among Dehydrogenases

1975 • 607 citations

Nucleoside diphosphate kinase from human erythrocytes. Structural characterization of the two polypeptide chains responsible for heterogeneity of the hexameric enzyme

1991 • 420 citations

Identification of a second human nm23 gene, nm23-H2.

1991 • 357 citations

A Drosophila gene that is homologous to a mammalian gene associated with tumor metastasis codes for a nucleoside diphosphate kinase

1990 • 353 citations

Binding of nucleotides by proteins

1992 • 274 citations

9 Nucleoside Diphosphokinases

1973 • 274 citations

Altered expression of NM23, a gene associated with low tumor metastatic potential, during adenovirus 2 Ela inhibition of experimental metastasis.

1988 • 264 citations

A serine phosphorylation of Nm23, and not its nucleoside diphosphate kinase activity, correlates with suppression of tumor metastatic potential.

1993 • 214 citations

X-ray structure of nucleoside diphosphate kinase.

1992 • 191 citations

Properties of Mutants of Drosophila Melanogaster and Changes During Development as Revealed by Paper Chromatography

1951 • 188 citations

Isolation and characterization of a cDNA clone encoding rat nucleoside diphosphate kinase.

1990 • 158 citations

Analysis of the lethal interaction between the prune and Killer of prune mutations of Drosophila.

1988 • 135 citations

Crystal Structure of Myxococcus xanthus Nucleoside Diphosphate Kinase and its Interaction with a Nucleotide Substrate at 2·0 Å Resolution

1993 • 121 citations

A Pro/Ser substitution in nucleoside diphosphate kinase of Drosophila melanogaster (mutation killer of prune) affects stability but not catalytic efficiency of the enzyme.

1992 • 120 citations

Molecular consequences of awdb3, a cell-autonomous lethal mutation of Drosophila induced by hybrid dysgenesis

1988 • 98 citations

Crystal structure of the Awd nucleotide diphosphate kinase from Drosophila

1993 • 94 citations

A HIGHLY SPECIFIC COMPLEMENTARY LETHAL SYSTEM IN DROSOPHILA MELANOGASTER

1956 • 94 citations

Purification of a multiprotein complex containing centrosomal proteins from the Drosophila embryo by chromatography with low-affinity polyclonal antibodies.

1992 • 92 citations

Adenosine 5'-diphosphate binding and the active site of nucleoside diphosphate kinase

1994 • 89 citations

A second form (beta isoform) of nucleoside diphosphate kinase from rat. Isolation and characterization of complementary and genomic DNA and expression.

1993 • 77 citations

Investigation of the active site and the conformational stability of nucleoside diphosphate kinase by site-directed mutagenesis.

1994 • 77 citations

X-ray structure of nucleoside diphosphate kinase complexed with thymidine diphosphate and Mg2+ at 2-.ANG. resolution

1994 • 76 citations

Molecular cloning and functional expression of the second mouse nm23/NDP kinase gene, nm23‐M2

1992 • 71 citations

A product of the prune locus of Drosophila is similar to mammalian GTPase-activating protein

1991 • 70 citations

Autophosphorylation of nucleoside diphosphate kinase from Myxococcus xanthus

1993 • 68 citations

Separate nuclear genes encode cytosolic and mitochondrial nucleoside diphosphate kinase in Dictyostelium discoideum.

1993 • 65 citations

The Expression of the Drosophila awd Gene during Normal Development and in Neoplastic Brain Tumors Caused by lgl Mutations

1993 • 50 citations

The amino acid sequence of nucleoside diphosphate kinase I from spinach leaves, as deduced from the cDNA sequence

1992 • 49 citations

Preparation of Crystalline Nucleoside Diphosphate Kinase from Baker's Yeast and Identification of 1‐[³²P]Phosphohistidine as the Main Phosphorylated Product of an Alkaline Hydrolysate of Enzyme Incubated with Adenosine [³²P]Triphosphate

1969 • 47 citations

Erythrocytic nucleoside diphosphokinase. IV. Evidence for electrophoretic heterogeneity

1971 • 42 citations

Autophosphorylation of nucleoside diphosphate kinase on non-histidine residues

1994 • 40 citations

Molecular Weight, Sulfhydryl Content, and Phosphorylation of a Homogeneous Mitochondrial Nucleoside Diphosphokinase

1968 • 36 citations

Nucleotide sequence of the cDNA encoding nucleoside diphosphate kinase II from spinach leaves

1993 • 25 citations

The mRNA product of the Drosophila gene prune is spliced and encodes a protein containing a putative transmembrane domain

1994 • 9 citations

Assay of Nucleoside Diphosphate Kinase in Microtiter Plates Using a Peroxidase-Coupled Method

1993 • 6 citations