Lithium treatment of affective disorders: effects of lithium on the inositol phospholipid and cyclic AMP signalling pathways

A highly sensitive adenylate cyclase assay

1974 • 4,213 citations

Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands

1982 • 2,148 citations

Neural and developmental actions of lithium: A unifying hypothesis

1989 • 1,005 citations

Drug Therapy in the Prevention of Recurrences in Unipolar and Bipolar Affective Disorders

1984 • 569 citations

Lithium inhibits adrenergic and cholinergic increases in GTP binding in rat cortex

1988 • 474 citations

Inositol phosphates: synthesis and degradation.

1988 • 359 citations

Lithium Carbonate Addition in Tricyclic Antidepressant—Resistant Unipolar Depression

1983 • 297 citations

Lithium Carbonate Augmentation of Antidepressant Treatment

1983 • 285 citations

A review of the biochemical and neuropharmacological actions of lithium

1987 • 171 citations

Effects of lithium on brain adenyl cyclase activity

1971 • 151 citations

Lithium-induced reduction in intracellular inositol supply in cholinergically stimulated parotid gland

1986 • 121 citations

Potentiation by lithium of CMP-phosphatidate formation in carbachol-stimulated rat cerebral-cortical slices and its reversal by myo-inositol

1989 • 115 citations

A high-performance liquid chromatographic method to measure 32P incorporation into phosphorylated metabolites in cultured cells

1982 • 113 citations

Formation and metabolism of [3H]inositol phosphates in AR42J pancreatoma cells. Substance P-induced Ca2+ mobilization in the apparent absence of inositol 1,4,5-trisphosphate 3-kinase activity.

1988 • 104 citations

Reduced inositol polyphosphate accumulation and inositol supply induced by lithium in stimulated cerebral cortex slices

1990 • 97 citations

Effects of GTP on hormone-stimulated adenylate cyclase activity in cerebral cortex, striatum, and hippocampus from rats treated chronically with lithium

1989 • 87 citations

Determination of mass changes in phosphatidylinositol 4,5-bisphosphate and evidence for agonist-stimulated metabolism of inositol 1,4,5-trisphosphate in airway smooth muscle

1991 • 85 citations

Lithium inhibits muscarinic-receptor-stimulated inositol tetrakisphosphate accumulation in rat cerebral cortex

1987 • 78 citations

Mode of Action of Lithium on the Catalytic Unit of Adenylate Cyclase from Rat Brain

1987 • 71 citations

The effects of lithium in vitro and ex vivo on adenylate cyclase in brain are exerted by distinct mechanisms

1989 • 62 citations

Lithium at therapeutic concentrations inhibits human brain noradrenaline-sensitive cyclic AMP accumulation

1983 • 51 citations

The Current Status of Lithium Therapy: Report of the APA Task Force

1975 • 47 citations

The Second-Messenger Dysbalance Hypothesis of Affective Disorders

1990 • 45 citations

Inositol Phospholipid Hydrolysis and Potentiation of Cyclic AMP Formation by Noradrenaline in Rat Cerebral Cortex Slices Are Not Mediated by the Same α‐Adrenoceptor Subtypes

1989 • 32 citations

The influence of adrenalectomy on α-adrenoceptor responses in rat cerebral cortex slices

1990 • 15 citations

Adenylate Cyclase and the Search for New Compounds with the Clinical Profile of Lithium

1984 • 10 citations