Metabolic interconversions between imipramine, its N-oxide, and its desmethyl derivative in rat tissues in vitro

Formation of an intermediate N-oxide in the oxidative demethylation of N,N-dimethylaniline catalyzed by liver microsomes

1964 • 212 citations

The metabolism of imipramine and its metabolites by rat liver microsomes

1966 • 77 citations

Chemical and enzymic rearrangements of N,N-dimethyl amino acid oxides

1956 • 46 citations

N-oxide formation: a new route for inactivation of the antihistaminic chlorcyclizine.

1967 • 42 citations

The oxidative demethylation of 1-propoxyphene and 1-propoxyphene n-oxide by rat liver microsomes

1964 • 36 citations