Supragranular mossy fiber sprouting is not necessary for spontaneous seizures in the intrahippocampal kainate model of epilepsy in the rat

Modification of seizure activity by electrical stimulation: II. Motor seizure

1972 • 6,939 citations

Fos and jun: The AP-1 connection

1988 • 1,597 citations

Mossy fiber synaptic reorganization in the epileptic human temporal lobe

1989 • 1,150 citations

Evidence of functional mossy fiber sprouting in hippocampal formation of kainic acid-treated rats

1985 • 1,101 citations

Synaptic reorganization by mossy fibers in human epileptic fascia dentata

1991 • 666 citations

Temporal lobe epilepsy

1977 • 425 citations

Possible functional consequences of synaptic reorganization in the dentate gyrus of kainate-treated rats

1992 • 369 citations

Electrographic Seizures and New Recurrent Excitatory Circuits in the Dentate Gyrus of Hippocampal Slices from Kainate-Treated Epileptic Rats

1996 • 361 citations

Chronic seizures and collateral sprouting of dentate mossy fibers after kainic acid treatment in rats

1988 • 341 citations

Hippocampal mossy fiber sprouting and synapse formation after status epilepticus in rats: Visualization after retrograde transport of biocytin

1995 • 339 citations

The product of a fos-related gene, fra-1, binds cooperatively to the AP-1 site with Jun: transcription factor AP-1 is comprised of multiple protein complexes.

1989 • 318 citations

CA3-Driven Hippocampal-Entorhinal Loop Controls Rather than SustainsIn VitroLimbic Seizures

1997 • 308 citations

Long-term effects of intrahippocampal kainic acid injection in rats: A method for inducing spontaneous recurrent seizures

1982 • 299 citations

Electrophysiology of dentate granule cells after kainate-induced synaptic reorganization of the mossy fibers

1992 • 279 citations

Physiologic and Morphologic Characteristics of Granule Cell Circuitry in Human Epileptic Hippocampus

1995 • 270 citations

The pathogenic and progressive features of chronic human hippocampal epilepsy

1996 • 234 citations

Suppression of pilocarpine-induced status epilepticus and the late development of epilepsy in rats

1995 • 188 citations

Single mossy fiber axonal systems of human dentate granule cells studied in hippocampal slices from patients with temporal lobe epilepsy.

1993 • 175 citations

Axonal Sprouting of CA1 Pyramidal Cells in Hyperexcitable Hippocampal Slices of Kainate‐treated Rats

1996 • 172 citations

Blockade of pilocarpine- or kainate-induced mossy fiber sprouting by cycloheximide does not prevent subsequent epileptogenesis in rats

1997 • 160 citations

Lesion-induced axonal sprouting and hyperexcitability in the hippocampus in vitro: Implications for the genesis of posttraumatic epilepsy

1997 • 159 citations

Hippocampal EEG excitability and chronic spontaneous seizures are associated with aberrant synaptic reorganization in the rat intrahippocampal kainate model

1993 • 152 citations

Null Mutation of c-fosImpairs Structural and Functional Plasticities in the Kindling Model of Epilepsy

1996 • 135 citations

In contrast to kindled seizures, the frequency of spontaneous epilepsy in the limbic status model correlates with greater aberrant fascia dentata excitatory and inhibitory axon sprouting, and increased staining for N-methyl-d-aspartate, AMPA and GABAA receptors

1997 • 135 citations

The functional relationship between antidromically evoked field responses of the dentate gyrus and mossy fiber reorganization in temporal lobe epileptic patients

1992 • 132 citations

Quantified patterns of mossy fiber sprouting and neuron densities in hippocampal and lesional seizures

1995 • 127 citations

Single mossy fiber axonal systems of human dentate granule cells studied in hippocampal slices from patients with temporal lobe epilepsy [published erratum appears in J Neurosci 1993 Jun;13(6):following table of contents]

1993 • 109 citations

Cycloheximide prevents kainate-induced neuronal death and c-fos expression in adult rat brain

1993 • 107 citations

Physiologic properties of human dentate granule cells in slices prepared from epileptic patients

1991 • 98 citations

NMDA receptor blockade prevents kainate induction of protein F1/GAP-43 mRNA in hippocampal granule cells and subsequent mossy fiber sprouting in the rat

1995 • 89 citations

NMDA receptor-mediated excitability in dendritically deformed dentate granule cells in pilocarpine-treated rats

1991 • 75 citations

Expression of GAP‐43 in the Granule Cells of Rat Hippocampus After Seizure‐induced Sprouting of Mossy Fibres: In Situ Hybridization and Immunocytochemical Studies

1994 • 70 citations

Spontaneous and stimulation-induced synchronized burst afterdischarges in the isolated CA1 of kainate-treated rats

1996 • 65 citations

Mossy fibre sprouting

1997 • 58 citations

Glutamate AMPA receptors in the fascia dentata of human and kainate rat hippocampal epilepsy

1996 • 55 citations

Kainic acid induced hippocampal seizures in rats: comparisons of acute and chronic seizures using intrahippocampal versus systemic injections

1995 • 50 citations

Hippocampal resections and the use of human tissue in defining temporal lobe epilepsy syndromes

1994 • 50 citations

Identification of a Novel Repressive Element That Contributes to Neuron-Specific Gene Expression

1997 • 49 citations

Slow Na+ channel inactivation and bursting discharge in a simple model axon: implications for neuropathic pain

1997 • 25 citations

Decreased time constant in hippocampal dentate granule cells in pilocarpine-treated rats with progressive seizure frequencies

1996 • 18 citations

Delayed development of spontaneous seizures and prolonged convulsive state in rats after massed stimulation of the anterior piriform cortex

1997 • 16 citations

Ultrastructural immunolocalization of GAP-43 in the sprouted mossy fibres of kainic acid lesioned rats

1994 • 14 citations

Cycloheximide inhibits kainic acid-induced GAP-43 mRNA in dentate granule cells in rats

1996 • 11 citations