AML and Ets proteins regulate the Iα1 germ-line promoter

Oncogenic Transcription Factors in the Human Acute Leukemias

1997 • 1,227 citations

t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1.

1991 • 897 citations

A human Mad protein acting as a BMP-regulated transcriptional activator

1996 • 674 citations

Interleukin 10 and transforming growth factor beta cooperate to induce anti-CD40-activated naive human B cells to secrete immunoglobulin A.

1992 • 641 citations

PEBP2/PEA2 represents a family of transcription factors homologous to the products of the Drosophila runt gene and the human AML1 gene.

1993 • 621 citations

Transforming growth factor beta specifically enhances IgA production by lipopolysaccharide-stimulated murine B lymphocytes.

1989 • 567 citations

Molecular Cloning and Characterization of PEBP2β, the Heterodimeric Partner of a Novel Drosophila runt-Related DNA Binding Protein PEBP2α

1993 • 504 citations

Cloning and Characterization of Subunits of the T-Cell Receptor and Murine Leukemia Virus Enhancer Core-Binding Factor

1993 • 425 citations

The t(8;21) Fusion Protein Interferes with AML-1B-Dependent Transcriptional Activation

1995 • 391 citations

Shutdown of Class Switch Recombination by Deletion of a Switch Region Control Element

1993 • 340 citations

Cloning and characterization of subunits of the T-cell receptor and murine leukemia virus enhancer core-binding factor.

1993 • 229 citations

Isolation of PEBP2 alpha B cDNA representing the mouse homolog of human acute myeloid leukemia gene, AML1.

1993 • 229 citations

The Immunoglobulin Class Switch: Beyond “Accessibility”

1997 • 217 citations

Cooperative binding of Ets-1 and core binding factor to DNA.

1994 • 216 citations

A selective defect in IgG2b switching as a result of targeted mutation of the I gamma 2b promoter and exon.

1993 • 206 citations

PEBP2 alpha B/mouse AML1 consists of multiple isoforms that possess differential transactivation potentials.

1994 • 204 citations

Qualitative and quantitative aspects of haematopoietic cell development in the mammalian embryo

1998 • 193 citations

Calcium/calmodulin inhibition of basic-helix-loop-helix transcription factor domains

1994 • 170 citations

History of Oral Tolerance and Mucosal Immunitya

1996 • 158 citations

Transactivation of the Moloney murine leukemia virus and T-cell receptor beta-chain enhancers by cbf and ets requires intact binding sites for both proteins

1995 • 153 citations

The Missing Bone

1997 • 149 citations

AML1A and AML1B can transactivate the human IL-3 promoter.

1997 • 130 citations

Replacement of germ-line epsilon promoter by gene targeting alters control of immunoglobulin heavy chain class switching.

1993 • 114 citations

Regulation of transcription of the germ-line Ig alpha constant region gene by an ATF element and by novel transforming growth factor-beta 1-responsive elements.

1992 • 93 citations

IgA class switch in I alpha exon-deficient mice. Role of germline transcription in class switch recombination.

1996 • 90 citations

Molecular analysis of IgA deficiency. Evidence for impaired switching to IgA.

1994 • 81 citations

A Novel Transcript Encoding an N-Terminally Truncated AML1/PEBP2αB Protein Interferes with Transactivation and Blocks Granulocytic Differentiation of 32Dcl3 Myeloid Cells

1997 • 79 citations

Binding of SL3-3 enhancer factor 1 transcriptional activators to viral and chromosomal enhancer sequences

1991 • 70 citations

The human l_α1 and l_α2 germline promoter elements: proximal positive and distal negative elements may regulate the tissue specific expression of C_α1 and C_α2 germline transcripts

1993 • 39 citations

The anti‐inflammatory effect of an oral immunoglobulin (IgA‐IgG) preparation and its possible relevance for the prevention of necrotizing enterocolitis

1994 • 35 citations

The human I_α1 region contains a TGF–β1 responsive enhancer and a putative recombination hotspot

1995 • 27 citations

Purification of SEF1 proteins binding to transcriptional enhancer elements active in T lymphocytes.

1993 • 14 citations

Failure of IgG production due to a defect in the opening of the chromatin structure of Iγ1 region in a patient with IgG and IgA deficiency

1995 • 2 citations