Detection of rare partially folded molecules in equilibrium with the native conformation of RNaseH

Primary structure effects on peptide group hydrogen exchange

1993 • 1,851 citations

Denaturant m values and heat capacity changes: Relation to changes in accessible surface areas of protein unfolding

1995 • 1,706 citations

Protein Folding

1992 • 1,601 citations

The molten globule state as a clue for understanding the folding and cooperativity of globular‐protein structure

1989 • 1,446 citations

X-Ray Structure of the GCN4 Leucine Zipper, a Two-Stranded, Parallel Coiled Coil

1991 • 1,433 citations

Hydrogen exchange and structural dynamics of proteins and nucleic acids

1983 • 1,329 citations

INTERMEDIATES IN THE FOLDING REACTIONS OF SMALL PROTEINS

1990 • 1,133 citations

Hydrogen Exchange in Proteins

1966 • 1,115 citations

Protein Folding Intermediates: Native-State Hydrogen Exchange

1995 • 980 citations

Backbone Dynamics of Ribonuclease HI: Correlations with Structure and Function in an Active Enzyme

1995 • 965 citations

How does a protein fold?

1994 • 947 citations

The importance of not saturating water in protein NMR. Application to sensitivity enhancement and NOE measurements

1993 • 891 citations

Formation of a Molten Globule Intermediate Early in the Kinetic Folding Pathway of Apomyoglobin

1993 • 735 citations

Evidence for a molten globule state as a general intermediate in protein folding

1990 • 677 citations

Comparison of different modes of two-dimensional reverse-correlation NMR for the study of proteins

1990 • 510 citations

The barriers in protein folding

1994 • 436 citations

PATHWAYS OF PROTEIN FOLDING

1993 • 435 citations

Three-dimensional structure of ribonuclease H from E. coli

1990 • 348 citations

Comparison of techniques for 1H-detected heteronuclear 1H15N Spectroscopy

1990 • 251 citations

Guanidinium Chloride Induction of Partial Unfolding in Amide Proton Exchange in RNase A

1993 • 176 citations

IVE (Image Visualization Environment): A Software Platform for All Three-Dimensional Microscopy Applications

1996 • 147 citations

Protein Folding: Solid evidence for molten globules

1994 • 118 citations

Temperature and pH Dependences of Hydrogen Exchange and Global Stability for Ovomucoid Third Domain

1996 • 82 citations

Hydrogen exchange in unligated and ligated staphylococcal nuclease

1993 • 77 citations

Equilibrium unfolding of Escherichia coli ribonuclease H: Characterization of a partially folded state

1994 • 71 citations

Relationship between Equilibrium Amide Proton Exchange Behavior and the Folding Pathway of Barnase

1995 • 70 citations

Structure of the Acid State of Escherichia coli Ribonuclease HI

1996 • 60 citations

Folding Pathway of Escherichia coli Ribonuclease HI: A Circular Dichroism, Fluorescence, and NMR Study

1995 • 54 citations

Characterization of the internal motions of Escherichia coli ribonuclease HI by a combination of 15N-NMR relaxation analysis and molecular dynamics simulation: examination of dynamic models

1995 • 44 citations

Hydrogen-Deuterium Exchange in the Free and Immunoglobulin G-Bound Protein G B-Domain

1994 • 37 citations

Intermediates In The Folding Reactions Of Small Proteins

1990 • 35 citations