Epidemiologic analyses of causation: the unlearned scientific lessons of randomized trials

Clinical Epidemiology: The Architecture of Clinical Research.

1985 • 952 citations

Influence of Adherence to Treatment and Response of Cholesterol on Mortality in the Coronary Drug Project

1980 • 628 citations

Efficacy of Tonsillectomy for Recurrent Throat Infection in Severely Affected Children

1984 • 500 citations

Clinical Epidemiology: The Architecture of Clinical Research

1985 • 463 citations

Coronary artery surgery study (CASS): A randomized trial of coronary artery bypass surgery

1984 • 414 citations

Alternative Analytic Methods for Case-Control Studies of Estrogens and Endometrial Cancer

1978 • 260 citations

An Additional Basic Science for Clinical Medicine: II. The Limitations of Randomized Trials

1983 • 257 citations

The problem of “protopathic bias” in case-control studies

1980 • 218 citations

SI UNITS

1974 • 150 citations

ASSURING THE QUALITY OF QUESTIONNAIRE DATA IN EPIDEMIOLOGIC RESEARCH

1979 • 104 citations

A Collection of 56 Topics with Contradictory Results in Case-Control Research

1988 • 88 citations

Oral contraceptives and cervical cancer risk in Costa Rica. Detection bias or causal association?

1988 • 74 citations

A Controlled Trial of Prophylactic Portacaval-Shunt Surgery

1964 • 71 citations

Coffee and pancreatic cancer. The problems of etiologic science and epidemiologic case-control research

1981 • 61 citations

The experimental paradigm and observational studies of cause-effect relationships in clinical medicine

1987 • 58 citations

CAUSALITY INFERENCE IN OBSERVATIONAL VS. EXPERIMENTAL STUDIES

1988 • 50 citations

The application of therapeutic-trial principles to improve the design of epidemiologic research: A case-control study suggesting that anticoagulants reduce mortality in patients with myocardial infarction

1981 • 41 citations

Oral contraceptives and cervical cancer risk in Costa Rica. Detection bias or causal association?

1988 • 26 citations

An algebraic analysis of biases due to exclusion, susceptibility, and protopathic prescription in case-control research

1981 • 25 citations

The 'epidemiologic necropsy'. Unexpected detections, demographic selections, and changing rates of lung cancer

1987 • 23 citations

Drug therapeutics : concepts for physicians

1979 • 12 citations