Detection of single-strand breaks and formamidopyrimidine-DNA glycosylase-sensitive sites in DNA of cultured human fibroblasts

Oxidants, antioxidants, and the degenerative diseases of aging.

1993 • 6,011 citations

Instability and decay of the primary structure of DNA

1993 • 5,370 citations

8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G-T and A-C substitutions.

1992 • 1,830 citations

DNA damage by oxygen‐derived species Its mechanism and measurement in mammalian systems

1991 • 1,555 citations

Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine.

1990 • 1,100 citations

Direct enzymic detection of endogenous oxidative base damage in human lymphocyte DNA

1993 • 831 citations

The role of 8-hydroxyguanine in carcinogenesis

1990 • 732 citations

Mechanistic studies of ionizing radiation and oxidative mutagenesis: genetic effects of a single 8-hydroxyguanine (7-hydro-8-oxoguanine) residue inserted at a unique site in a viral genome

1990 • 687 citations

8-oxoguanine (8-hydroxyguanine) DNA glycosylase and its substrate specificity.

1991 • 678 citations

Hydroxyl Free Radical Adduct of Deoxyguanosine: Sensitive Detection and Mechanisms of Formation

1986 • 660 citations

Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: definition of a family of DNA repair enzymes.

1991 • 526 citations

Enzymatic Synthesis of Deoxyribonucleic Acid

1970 • 424 citations

Molecular mechanisms of oxygen radical carcinogenesis and mutagenesis: The role of dna base damage

1990 • 364 citations

Homogeneous Escherichia coli FPG protein. A DNA glycosylase which excises imidazole ring-opened purines and nicks DNA at apurinic/apyrimidinic sites.

1990 • 347 citations

gamma Ray induced deoxyribonucleic acid strand breaks. 3' Glycolate termini.

1983 • 319 citations

Site-specific mutagenesis using a gapped duplex vector: A study of translesion synthesis past 8-oxodeoxyguanosine in E. coli

1991 • 309 citations

Two distinct human DNA diesterases that hydrolyze 3′-blocking deoxyribose fragments from oxidized DNA

1991 • 265 citations

Formation of 8-hydroxyguanine moiety in deoxyribonucleic acid on .gamma.-irradiation in aqueous solution

1985 • 224 citations

An endonuclease activity of Escherichia coli that specifically removes 8-hydroxyguanine residues from DNA

1991 • 149 citations

DNA Radiolysis by Fast Neutrons

1990 • 117 citations

Phenol sensitization of DNA to subsequent oxidative damage in 8-hydroxyguanine assays

1992 • 113 citations

An endonuclease activity in human polymorphonuclear neutrophils that removes 8-hydroxyguanine residues from DNA

1991 • 84 citations

Repair and replication of plasmids with site-specific 8-oxodG and 8-AAFdG residues in normal and repair-deficient human cells

1992 • 83 citations

Xeroderma pigmentosum, Cockayne's syndrome, helicases, and DNA repair: What's the relationship?

1992 • 81 citations

Nick translation—a new assay for monitoring dna damage and repair in cultured human fibroblasts

1985 • 65 citations

Detection of carcinogen-induced DNA breaks by nick translation in permeable cells

1983 • 41 citations

Detection of DNA single-strand breaks in lymphocytes of smokers

1993 • 35 citations