Crystallographic studies on apocarboxypeptidase A and the complex with glycyl-L-tyrosine.

Design of Specific Inhibitors of Angiotensin-Converting Enzyme: New Class of Orally Active Antihypertensive Agents

1977 • 1,851 citations

Serine Proteases: Structure and Mechanism of Catalysis

1977 • 1,238 citations

A new class of angiotensin-converting enzyme inhibitors

1980 • 704 citations

Carboxypeptidase A: A Protein and an Enzyme

1971 • 396 citations

Refined crystal structure of carboxypeptidase a at 1·54 Å resolution

1983 • 391 citations

Carboxypeptidase A. Differences in the mechanisms of ester and peptide hydrolysis

1974 • 148 citations

Inhibition of thermolysin and carboxypeptidase A by phosphoramidates

1979 • 138 citations

The difference Fourier technique in protein crystallography: errors and their treatment

1971 • 137 citations

CARBOXYPEPTIDASE, A ZINC METALLOENZYME

1955 • 133 citations

Design of potent and specific inhibitors of carboxypeptidases A and B

1979 • 117 citations

Crystallographic structure refinement of Chromatium high potential iron protein at two Angstroms resolution.

1975 • 104 citations

Catalytic role of the metal ion of carboxypeptidase A in ester hydrolysis.

1979 • 104 citations

The Structure of Carboxypeptidase A

1967 • 85 citations

Zinc environment and cis peptide bonds in carboxypeptidase A at 1.75-A resolution.

1981 • 78 citations

Metallocarboxypeptidases: Mechanism of Inhibition by Chelating Agents, Mercaptans, and Metal Ions^*

1962 • 62 citations

Binding of ligands to the active site of carboxypeptidase A.

1981 • 57 citations

Apocarboxypeptidase-substrate Complexes

1962 • 55 citations

Changes in the three-dimensional structure of concanavalin A upon demetallization

1978 • 50 citations

Hydrolysis of esters by carboxypeptidase A requires a penta-coordinate metal ion.

1982 • 49 citations

Crystal structure of demetallized concanavalin A: the metal-binding region

1979 • 49 citations

Cryospectroscopy of intermediates in the mechanism of carboxypeptidase A

1983 • 46 citations

The structure of carboxypeptidase A. VII. The 2.0-angstrom resolution studies of the enzyme and of its complex with glycyltyrosine, and mechanistic deductions.

1968 • 45 citations

Cryokinetic studies of the intermediates in the mechanism of carboxypeptidase A

1983 • 43 citations

Structure of an actively exchanging complex between carboxypeptidase A and a substrate analogue.

1980 • 31 citations

Kinetics of Formation and Dissociation of Metallocarboxypeptidases

1978 • 25 citations