Thrombin increases proliferation and decreases fibrinolytic activity of kidney glomerular epithelial cells

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Detection of an unusually stable fibrinolytic inhibitor produced by bovine endothelial cells.

1983 • 400 citations

The activation of pro-urokinase by plasma kallikrein and its inactivation by thrombin.

1986 • 391 citations

Autocrine saturation of pro-urokinase receptors on human A431 cells

1986 • 361 citations

Phosphoinositides in mitogenesis: Neomycin inhibits thrombin-stimulated phosphoinositide turnover and initiation of cell proliferation

1985 • 332 citations

Thrombin stimulates tissue plasminogen activator release from cultured human endothelial cells.

1984 • 330 citations

Control of proliferation of human vascular endothelial cells. Characterization of the response of human umbilical vein endothelial cells to fibroblast growth factor, epidermal growth factor, and thrombin

1978 • 312 citations

Thrombin induction of plasminogen activator-inhibitor in cultured human endothelial cells.

1986 • 310 citations

Insulin Stimulates the Synthesis of Plasminogen Activator Inhibitor 1 by the Human Hepatocellular Cell Line Hep G2

1988 • 303 citations

Characterization of the Cellular Binding Site for the Urokinase-type Plasminogen Activator

1989 • 248 citations

Binding of human thrombin to cultured human endothelial cells.

1979 • 193 citations

Thrombin^a

1986 • 186 citations

Glucocorticoid-modulated gene expression of tissue- and urinary-type plasminogen activator and plasminogen activator inhibitor 1 and 2.

1988 • 168 citations

Plasminogen activator inhibitor is associated with the extracellular matrix of cultured bovine smooth muscle cells.

1987 • 158 citations

Human glomerular cells in vitro: isolation and characterization.

1980 • 154 citations

Phorbol ester induces the biosynthesis of glycosylated and nonglycosylated plasminogen activator inhibitor 2 in high excess over urokinase-type plasminogen activator in human U-937 lymphoma cells.

1987 • 149 citations

Role of specific cell surface receptors in thrombin-stimulated cell division

1978 • 119 citations

The fibrinolytic system in man

1986 • 98 citations

Macrophage-induced glomerular fibrin deposition in experimental glomerulonephritis in the rabbit.

1985 • 95 citations

Thrombin regulation of mRNA levels of tissue plasminogen activator and plasminogen activator inhibitor-1 in cultured human umbilical vein endothelial cells

1989 • 90 citations

Thrombin Active-Site Regions

1986 • 85 citations

Thrombin regulation of mRNA levels of tissue plasminogen activator and plasminogen activator inhibitor-1 in cultured human umbilical vein endothelial cells

1989 • 74 citations

Double-Signal Hypothesis for Thrombin Initiation of Cell Proliferation

1986 • 72 citations

Stimulation of human vascular endothelial cell growth by a platelet-derived growth factor and thrombin

1979 • 62 citations

Characterization of a plasminogen activator and its inhibitor in human mesangial cells

1989 • 51 citations

The participation of macrophages, glomerular procoagulant activity, and factor VIII in glomerular fibrin deposition. Studies on anti-GBM antibody-induced glomerulonephritis in rabbits.

1986 • 49 citations

Urokinase synthesis and binding by glomerular epithelial cells in culture

1989 • 49 citations

Receptor-mediated chemotactic response of a macrophage cell line (J774) to thrombin.

1983 • 44 citations

Thrombin receptor occupancy initiates cell proliferation in the presence of phorbol myristic acetate

1986 • 23 citations

A novel method for measuring cell surface-bound thrombin. Detection of iodination-induced changes in thrombin-binding affinity.

1982 • 21 citations

Enhanced glomerular procoagulant activity and fibrin deposition in rats with mercuric chloride-induced autoimmune nephritis.

1987 • 19 citations

Thrombin‐Receptor Occupancy Initiates a Transient Increase in CAMP Levels in Mitogenically Responsive Hamster (NIL) Fibroblasts^a

1986 • 18 citations

Quantitative assessment of procoagulant activity in isolated rat glomeruli

1985 • 18 citations

ENHANCED GLOMERULAR PROCOAGULANT ACTIVITY AND FIBRIN DEPOSITION IN RATS WITH MERCURIC CHLORIDE-INDUCED AUTOIMMUNE NEPHRITIS

1987 • 14 citations

Glomerular hemostasis in normal and pathologic conditions.

1988 • 14 citations

Monoclonal antibody to the thrombin receptor stimulates DNA synthesis in combination with gamma-thrombin or phorbol myristate acetate.

1987 • 12 citations