Some properties of the phosphorothioate analogs of adenosine triphosphate as substrates of enzymic reactions

Enzyme-Catalyzed Phosphoryl Transfer Reactions

1980 • 1,120 citations

Synthesis and properties of diastereoisomers of adenosine 5'-(O-1-thiotriphosphate) and adenosine 5'-(O-2-thiotriphosphate)

1976 • 214 citations

³¹P nuclear magnetic resonance spectra of the thiophosphate analogs of adenine nucleotides; effects of pH and Mg²⁺ binding

1978 • 189 citations

A study of the mechanism of DNA polymerase I from Escherichia coli with diastereomeric phosphorothioate analogs of deoxyadenosine triphosphate.

1979 • 172 citations

Divalent cation-dependent stereospecificity of adenosine 5‘-O-(2-thiotriphosphate) in the hexokinase and pyruvate kinase reactions. The absolute stereochemistry of the diastereoisomers of adenosine 5‘-O-(2-thiotriphosphate).

1978 • 146 citations

Use of chromium-adenosine triphosphate and lyxose to elucidate the kinetic mechanism and coordination state of the nucleotide substrate for yeast hexokinase

1975 • 141 citations

Diastereomers of the nucleoside phosphorothioates as probes of the structure of the metal nucleotide substrates and of the nucleotide binding site of yeast hexokinase.

1979 • 131 citations

Phosphorothioate analogs of nucleotides

1979 • 127 citations

Substrate activity of (adenosine triphosphato)tetraamminecobalt(III) with yeast hexokinase and separation of diastereomers using the enzyme

1978 • 125 citations

Investigations of substrate specificity and reaction mechanism of several kinases using chromium(III) adenosine 5'-triphosphate and chromium(III) adenosine 5'-diphosphate

1980 • 112 citations

Is superoxide important in oxygen poisoning?

1982 • 98 citations

A monohydroxobridged, strongly antiferromagnetically coupled dicopper(II) center in a binucleating macrocycle. Comparisons with binuclear copper sites in biology

1981 • 93 citations

Equilibrium state of ATP-driven ion pumps in relation to physiological ion concentration gradients.

1981 • 80 citations

Stereochemical aspects of the interaction of myosin and actomyosin with nucleotides

1980 • 79 citations

Identification of the six ligands to manganese(II) in transition-state-analog complexes of creatine kinase: oxygen-17 superhyperfine coupling from selectively labeled ligands

1980 • 75 citations

Stereochemistry of internucleotide bond formation by polynucleotide phosphorylase from Micrococcus luteus

1979 • 57 citations

Structure of metal x nucleotide complex in the creatine kinase reaction. A study with diastereomeric phosphorothioate analogs of adenosine di- and triphosphate.

1980 • 50 citations

Crystal and Molecular Structure of Adenosine 5'-O-Phosphorothioate O-p-Nitrophenyl Ester (Sp Diastereomer). Substrate Stereospecificity of Snake Venom Phosphodiesterase

1979 • 48 citations

Mechanistic studies on deoxyribonucleic acid dependent ribonucleic acid polymerase from Escherichia coli using phosphorothioate analogs. 2. The elongation reaction

1979 • 48 citations

Reactivity and metal-dependent stereospecificity of the phosphorothioate analogs of ADP and ATP and reactivity of Cr(III)ATP in the 3-phosphoglycerate kinase reaction. Structure of the metal nucleotide substrates.

1982 • 30 citations

Structures of the mono- and divalent metal nucleotide complexes in the myosin ATPase.

1981 • 29 citations

Structure of the metal.nucleotide complex in the yeast phenylalanyl transfer ribonucleic acid synthetase reaction as determined with diastereomeric phosphorothioate analogs of ATP.

1980 • 28 citations

Structure of the metal-nucleotide complex in the acetate kinase reaction. A study with gamma-32P-labeled phosphorothioate analogs of ATP.

1981 • 27 citations

Thiophosphate analogs of ADP and ATP as substrates in partial reactions of energy conversion in chloroplasts

1979 • 25 citations

31P NMR quantitation of the displacement of equilibria of arginine, creatine, pyruvate, and 3-P-glycerate kinase reactions by substitution of sulfur for oxygen in the beta phosphate of ATP.

1980 • 23 citations

Reactivity and metal-dependent stereospecificity of the phosphorothioate analogs of ATP in the arginine kinase reaction. Structure of the metal-nucleoside triphosphate substrate.

1982 • 23 citations

.beta.- and .gamma.-Thio analogs of adenosine triphosphate as probes of the Escherichia coli valyl transfer ribonucleic acid synthetase reaction pathway. A novel stereospecific interchange of adenosine 5'-O-(2-thiotriphosphate) to adenosine 5'-O-(3-thiotriphosphate)

1979 • 23 citations

Stereochemistry of binding of thiophosphate analogs of ATP and ADP to carbamate kinase, glutamine synthetase, and carbamoyl-phosphate synthetase

1980 • 21 citations

Reactions of thio analogs of adenosine 5'-triphosphate catalyzed by methionyl-tRNA synthetase from Escherichia coli and metal dependence of stereospecificity

1982 • 20 citations

Synthesis, purification, and characterization of the A and B diastereomers of gamma-32P-labeled adenosine 5'-O-(2-thiotriphosphate).

1980 • 15 citations

Carbamyl phosphate synthetase of Escherichia coli uses the same diastereomer of adenosine-5'-[2-thiotriphosphate] at both ATP sites.

1978 • 13 citations

Shift of the equilibrium constant of the 3-P-glycerate kinase reaction towards 1,3-bis-P-glycerate with adenosine 5'-O-(2-thiotriphosphate) (ATP beta S) as substrate.

1980 • 11 citations

Interaction of sulfur‐containing ATP analogs with rabbit muscle phosphofructokinase

1979 • 8 citations