Differential Use of Transcription Activation Function 2 Domain of the Vitamin D Receptor by 1,25-Dihydroxyvitamin D3 and Its A Ring-Modified Analogs

Sequence and Characterization of a Coactivator for the Steroid Hormone Receptor Superfamily

1995 • 2,390 citations

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

1995 • 2,059 citations

A transcriptional co-repressor that interacts with nuclear hormone receptors

1995 • 1,744 citations

Structure-Function Relationships in the Vitamin D Endocrine System*

1995 • 1,182 citations

Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-α

1995 • 1,179 citations

Crystal structure of the RAR-γ ligand-binding domain bound to all-trans retinoic acid

1995 • 1,085 citations

The human estrogen receptor has two independent nonacidic transcriptional activation functions

1989 • 1,066 citations

Nuclear receptor coactivators and corepressors.

1996 • 917 citations

Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors.

1992 • 829 citations

Estrogen Receptor-Associated Proteins: Possible Mediators of Hormone-Induced Transcription

1994 • 645 citations

Polarity-specific activities of retinoic acid receptors determined by a co-repressor

1995 • 569 citations

Nuclear receptor coactivators and corepressors

1996 • 414 citations

The vitamin D-responsive element in the human osteocalcin gene. Association with a nuclear proto-oncogene enhancer.

1990 • 313 citations

1,25-Dihydroxycholecalciferol: Identification of the Proposed Active Form of Vitamin D ₃ in the Intestine

1971 • 216 citations

Distinct Conformational Changes Induced by 20-epi Analogues of 1α,25-Dihydroxyvitamin D3 Are Associated with Enhanced Activation of the Vitamin D Receptor

1995 • 201 citations

Demonstration that 1 beta,25-dihydroxyvitamin D3 is an antagonist of the nongenomic but not genomic biological responses and biological profile of the three A-ring diastereomers of 1 alpha,25-dihydroxyvitamin D3.

1993 • 182 citations

Evidence for Ligand-Dependent Intramolecular Folding of the AF-2 Domain in Vitamin D Receptor-Activated Transcription and Coactivator Interaction

1997 • 154 citations

The C-terminal region of the vitamin D receptor is essential to form a complex with a receptor auxiliary factor required for high affinity binding to the vitamin D-responsive element.

1994 • 105 citations

Differential Interaction of α,25-Dihydroxyvitamin D3 Analogues and Their 20-epi Homologues with the Vitamin D Receptor

1997 • 103 citations

Structure-function studies of 1,25-dihydroxyvitamin D3 and the vitamin D endocrine system. 1,25-dihydroxy-pentadeuterio-previtamin D3 (as a 6-s-cis analog) stimulates nongenomic but not genomic biological responses

1993 • 89 citations

Antiproliferative Hybrid Analogs of the Hormone 1α,25-Dihydroxyvitamin D₃: Design, Synthesis, and Preliminary Biological Evaluation

1997 • 80 citations

New vitamin D3 derivatives with unexpected antiproliferative activity: 1-(hydroxymethyl)-25-hydroxyvitamin D3 homologs

1992 • 63 citations

Transcription of the Human Calcitonin Gene is Mediated by a C Cell-Specific Enhancer Containing E-Box-Like Elements

1990 • 47 citations

A 20-epi side chain restores growth-regulatory and transcriptional activities of an A ring-modified hybrid analog of 1α,25-dihydroxyvitamin D3 without increasing its affinity to the vitamin D receptor

1996 • 38 citations

Asymmetric total synthesis, x-ray crystallography, and preliminary biological evaluation of 1-(1'-hydroxyethyl)-25-hydroxyvitamin D3 analogs of natural calcitriol

1993 • 31 citations

[58] Measurement of kinetic rate constants for the binding of 1α,25-dihydroxyvitamin D3 to its chick intestinal mucosa receptor using a hydroxyapatite batch assay

1980 • 23 citations

1α,25-dihydroxyvitamin D3 hybrid analogs with structural changes at both the A-ring and the C,D-ring side-chain

1994 • 22 citations

The role of vitamin D3 in immunosuppression: lessons from autoimmunity and transplantation.

1997 • 21 citations

Vitamin D and breast cancer: the therapeutic potential of new vitamin D analogues

1995 • 20 citations

1α,25-Dihydroxyvitamin D3 Hybrid Analogs with Structural changes at both the A-ring and the C,D-ring side-chain. II

1995 • 16 citations

Psoriasis and other skin diseases.

1997 • 15 citations