Quantitative autoradiography of dopamine-D1 receptors, D2 receptors, and dopamine uptake sites in postmortem striatal specimens from schizophrenic patients

Diagnostic and Statistical Manual of Mental Disorders

1988 • 12,705 citations

Diagnostic and Statistical Manual of Mental Disorders (3rd ed. rev.)

1988 • 5,237 citations

D ₁ and D ₂ Dopamine Receptor-regulated Gene Expression of Striatonigral and Striatopallidal Neurons

1990 • 2,873 citations

Dopamine Receptor Binding Predicts Clinical and Pharmacological Potencies of Antischizophrenic Drugs

1976 • 2,224 citations

Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine

1991 • 2,008 citations

New perspectives in basal forebrain organization of special relevance for neuropsychiatric disorders: The striatopallidal, amygdaloid, and corticopetal components of substantia innominata

1988 • 1,209 citations

[Biological psychiatry].

1980 • 1,087 citations

Positron Emission Tomography Reveals Elevated D ₂ Dopamine Receptors in Drug-Naive Schizophrenics

1986 • 935 citations

The neostriatal mosaic: II. Patch- and matrix-directed mesostriatal dopaminergic and non-dopaminergic systems

1987 • 788 citations

Adenylyl Cyclase Amino Acid Sequence: Possible Channel- or Transporter-Like Structure

1989 • 745 citations

Quantitative autoradiographic localization of the D1 and D2 subtypes of dopamine receptors in rat brain

1986 • 742 citations

A neurohistological correlate of schizophrenia.

1984 • 584 citations

Pronounced Reduction of Total Neuron Number in Mediodorsal Thalamic Nucleus and Nucleus Accumbens in Schizophrenics

1990 • 558 citations

D2 Dopamine Receptors in Neuroleptic-Naive Schizophrenic Patients

1990 • 526 citations

INCREASED DOPAMINE-RECEPTOR SENSITIVITY IN SCHIZOPHRENIA

1978 • 513 citations

Dopamine receptor sequences. Therapeutic levels of neuroleptics occupy D2 receptors, clozapine occupies D4.

1992 • 445 citations

Increased concentrations and lateral asymmetry of amygdala dopamine in schizophrenia

1983 • 412 citations

Increased Brain Dopamine and Dopamine Receptors in Schizophrenia

1982 • 393 citations

Binding of 3H-neuroleptics and 3H-apomorphine in schizophrenic brains

1978 • 351 citations

Bimodal Distribution of Dopamine Receptor Densities in Brains of Schizophrenics

1984 • 347 citations

Human brain D1 and D2 dopamine receptors in schizophrenia, Alzheimer's, Parkinson's, and Huntington's diseases

1987 • 322 citations

Abnormal dopamine uptake sites in postmortem striatum from patients with tourette's syndrome

1991 • 269 citations

Central Dopamine Turnover in Schizophrenic Syndromes

1974 • 268 citations

Cocaine receptors labeled by [3H]2 beta-carbomethoxy-3 beta-(4-fluorophenyl)tropane.

1989 • 248 citations

Decreased serotonin S2 and increased dopamine D2 receptors in chronic schizophrenics

1986 • 225 citations

Elevation of brain neuroleptic/dopamine receptors in schizophrenia

1980 • 220 citations

Monoamine Mechanisms in Chronic Schizophrenia: Post-Mortem Neurochemical Findings

1979 • 208 citations

Unique binding characteristics of antipsychotic agents interacting with human dopamine D2A, D2B, and D3 receptors.

1993 • 207 citations

INCREASED DOPAMINE CONCENTRATION IN LIMBIC AREAS OF BRAIN FROM PATIENTS DYING WITH SCHIZOPHRENIA

1979 • 203 citations

Link between D1 and D2 dopamine receptors is reduced in schizophrenia and Huntington diseased brain.

1989 • 197 citations

3H-spiperone binding sites in post-mortem brains from schizophrenic patients: Relationship to neuroleptic drug treatment, abnormal movements, and positive symptoms

1989 • 189 citations

Striatal D2 dopaminergic receptors assessed with positron emission tomography and [76Br]bromospiperone in untreated schizophrenic patients

1990 • 171 citations

Organization of dopamine D1 and D2 receptors in human striatum: Receptor autoradiographic studies in Huntington's disease and schizophrenia

1988 • 170 citations

3H-flupenthixol binding in post-mortem brains of schizophrenics: Evidence for a selective increase in dopamine D2 receptors

1981 • 165 citations

[3H]SCH 23390 binding to D1 dopamine receptors in the basal ganglia of the cat and primate: Delineation of striosomal compartments and pallidal and nigral subdivisions

1988 • 154 citations

Dopamine receptor subtype imbalance in schizophrenia

1987 • 141 citations

No Linkage Between D2 Dopamine Receptor Gene Region and Schizophrenia

1991 • 121 citations

Human striatal dopamine receptors are organized in compartments.

1986 • 120 citations

Distribution of D1 and D2 dopamine receptors in the basal ganglia of the cat determined by quantitative autoradiography

1988 • 94 citations

Cerebrospinal Fluid and Plasma Monoamine Metabolites and Their Relation to Psychosis

1990 • 94 citations

Chronic neuroleptic treatment increases D-2 but not D-1 receptors in rat striatum

1985 • 83 citations

Comparative development of D1-dopamine and μ opiate receptors in normal and in 6-hydroxydopamine-lesioned neonatal rat striatum: dopaminergic fibers regulate μ but not D1 receptor distribution

1991 • 59 citations

Striosomal organization of cholinergic and dopaminergic uptake sites and cholinergic M1 receptors in the adult human striatum: a quantitative receptor autoradiographic study

1990 • 40 citations

[3H] GBR 12935 binding to the dopamine uptake site in post-mortem brain tissue in schizophrenia

1989 • 32 citations

New substituted 1-phenyl-3-benzazepine analogues of SK&F 38393 and N-methyl-thienopyridine analogues of dihydroxynomifensine with selective affinity for the D-1 dopamine receptor in human post-mortem brain

1987 • 14 citations