Structure-specific inhibition of lysosomal cholesterol transport in macrophages by various steroids

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

Lysosomotropic agents

1974 • 1,887 citations

[19] Receptor-mediated endocytosis of low-density lipoprotein in cultured cells

1983 • 1,639 citations

The role of the monocyte in atherogenesis: I. Transition of blood-borne monocytes into foam cells in fatty lesions.

1981 • 1,325 citations

Reversible accumulation of cholesteryl esters in macrophages incubated with acetylated lipoproteins.

1979 • 545 citations

Role of acyl-CoA: cholesterol acyltransferase in cellular cholesterol metabolism.

1985 • 519 citations

Arterial foam cells with distinctive immunomorphologic and histochemical features of macrophages.

1980 • 475 citations

Inhibition of Sterol Synthesis in Cultured Mouse Cells by Cholesterol Derivatives Oxygenated in the Side Chain

1974 • 330 citations

Inhibition of Sterol Synthesis in Cultured Mouse Cells by 7α-Hydroxycholesterol, 7β-Hydroxycholesterol, and 7-Ketocholesterol

1973 • 320 citations

The intracellular transport of low density lipoprotein-derived cholesterol is inhibited in Chinese hamster ovary cells cultured with 3-β-[2-(diethylamino)ethoxy]androst-5-en-17-one

1989 • 315 citations

The intracellular transport of low density lipoprotein-derived cholesterol is defective in Niemann-Pick type C fibroblasts.

1989 • 306 citations

Low density lipoprotein (LDL)-mediated suppression of cholesterol synthesis and LDL uptake is defective in Niemann-Pick type C fibroblasts.

1987 • 249 citations

Rat liver acyl-coenzyme A:cholesterol acyltransferase: its regulation in vivo and some of its properties in vitro

1980 • 241 citations

Scavenger receptor-mediated uptake and metabolism of lipid vesicles containing acidic phospholipids by mouse peritoneal macrophages.

1990 • 231 citations

Group C Niemann‐Pick disease: faulty regulation of low‐density lipoprotein uptake and cholesterol storage in cultured fibroblasts

1987 • 196 citations

Intracellular cholesterol transport.

1992 • 196 citations

Progesterone blocks cholesterol translocation from lysosomes.

1992 • 170 citations

Type C Niemann-Pick disease. Abnormal metabolism of low density lipoprotein in homozygous and heterozygous fibroblasts.

1986 • 167 citations

Permeability properties of liposomes prepared from dipalmitoyllecithin, dimyristoyllecithin, egg lecithin, rat liver lecithin and beef brain sphingomyelin

1974 • 166 citations

The participation of sterol carrier protein2 in the conversion of cholesterol to cholesterol ester by rat liver microsomes.

1981 • 154 citations

The cholesterol storage disorder of the mutant BALB/c mouse. A primary genetic lesion closely linked to defective esterification of exogenously derived cholesterol and its relationship to human type C Niemann-Pick disease.

1986 • 134 citations

Acyl coenzyme A:cholesterol acyl transferase in macrophages utilizes a cellular pool of cholesterol oxidase-accessible cholesterol as substrate.

1988 • 134 citations

Sorting of an internalized plasma membrane lipid between recycling and degradative pathways in normal and Niemann-Pick, type A fibroblasts.

1990 • 123 citations

Isolation and characterization of Chinese hamster ovary cell mutants defective in intracellular low density lipoprotein-cholesterol trafficking.

1990 • 109 citations

Bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase, blocks lysosomal cholesterol trafficking in macrophages.

1993 • 102 citations

A new high-yield procedure for the purification of the non-specific phospholipid transfer protein from rat liver

1981 • 99 citations

Isolation and characterization of Chinese hamster ovary cells defective in the intracellular metabolism of low density lipoprotein-derived cholesterol.

1992 • 97 citations

Effects of 3.beta.-[2-(diethylamino)ethoxy]androst-5-en-17-one on the synthesis of cholesterol and ubiquinone in rat intestinal epithelial cell cultures

1983 • 95 citations

26-Hydroxycholesterol: synthesis, metabolism, and biologic activities

1990 • 82 citations

Increased cholesterol esterification in rat liver microsomes by purified non-specific phospholipid transfer protein

1982 • 65 citations

Regulation of acyl CoA:cholesterol acyltransferase by 25-hydroxycholesterol in rabbit intestinal microsomes and absorptive cells.

1983 • 59 citations

Esterification of cholesterol and 25-hydroxycholesterol by rat liver microsomes

1983 • 44 citations

The synthesis and esterification of cholesterol by hepatocytes and H35 hepatoma cells are independent of the level of nonspecific lipid transfer protein

1985 • 38 citations

Lysosome lipid storage disorder in NCTR-BALB/c mice. III. Isolation and analysis of storage inclusions from liver.

1982 • 26 citations

The hypocholesteremic effect of 3β-(β-dimethylaminoethoxy)-androst-5-en-17-one and its mechanism of action

1961 • 18 citations

Mobilization of acyl chains from endogenous cellular phospholipids into cholesteryl esters during foam-cell formation in mouse peritoneal macrophages

1993 • 16 citations

Differing Effects of Three Oxysterols on Low-Density Lipoprotein Metabolism in HepG2 Cells

1993 • 16 citations