Pharmacologic therapy for urticaria

Definition and Antagonism of Histamine H2-receptors

1972 • 2,284 citations

Highly potent and selective ligands for histamine H3-receptors

1987 • 890 citations

Goodman and Gilman's the pharmacologic basis of therapeutics

1991 • 586 citations

URTICARIA AND ANGIO-OEDEMA.

1969 • 553 citations

Histamine Release in vitro: Inhibition by Catecholamines and Methylxanthines

1968 • 458 citations

Recurrent urticaria: clinical investigation of 330 patients

1981 • 387 citations

Drill's Pharmacology in Medicine.

1972 • 303 citations

Astemizole

1984 • 258 citations

Histaminergic Mechanisms in Brain

1977 • 255 citations

Pharmacologic Control of Allergic Histamine Release in Vitro: Evidence for an Inhibitory Role of 3′,5′-Adenosine Monophosphate in Human Leukocytes

1972 • 227 citations

The pharmacological properties of a new, orally active antianaphylactic compound: ketotifen, a benzocycloheptathiophene.

1978 • 216 citations

Torsade de pointes after astemizole overdose.

1986 • 157 citations

Vascular reactions to histamine and compound 48/80 in human skin: suppression by a histamine H2‐receptor blocking agent.

1977 • 142 citations

Correlation between plasma diphenhydramine level and sedative and antihistamine effects

1978 • 138 citations

Loratadine

1989 • 134 citations

Double-blind crossover study comparing doxepin with diphenhydramine for the treatment chronic urticaria

1985 • 133 citations

Tricyclic antidepressants and histamine H1 receptors.

1979 • 130 citations

Prevention of Mast-Cell Degranulation by Ketotifen in Patients with Physical Urticarias

1986 • 126 citations

Cimetidine and chlorpheniramine in the treatment of chronic idiopathic urticaria: a multi-centre randomized double-blind study

1987 • 124 citations

Combined H1 and H2 Antihistamine Therapy in Chronic Urticaria

1981 • 120 citations

Performance studies with the H1‐histamine receptor antagonists, astemizole and terfenadine.

1982 • 115 citations

INHIBITION OF HISTAMINE RELEASE FROM HUMAN LUNG in vitro BY ANTIHISTAMINES AND RELATED DRUGS

1980 • 106 citations

Evaluation of the CNS properties of SCH 29851, a potential non-sedating antihistamine

1984 • 101 citations

RESPONSES OF HUMAN SKIN BLOOD VESSELS TO SYNTHETIC HISTAMINE ANALOGUES

1978 • 97 citations

In vitro and in vivo binding characteristics of a new long-acting histamine H1 antagonist, astemizole.

1982 • 97 citations

Terfenadine, an H₁Antihistamine, Inhibits Histamine ReleaseIn Vivoin the Human

1990 • 96 citations

Efficacy of doxepin in the treatment of chronic idiopathic urticaria

1986 • 96 citations

The inhibitory effect of antiallergy drugs on allergen and histamine induced wheal and flare response

1973 • 94 citations

A controlled trial of therapy in chronic urticaria

1981 • 92 citations

Inhibitory activity of terfenadine on histamine-induced skin wheals in man

1977 • 91 citations

ETIOLOGY AND PATHOGENESIS OF CHRONIC URTICARIA.

1965 • 87 citations

The effect of H1 and H2 histamine antagonists on symptomatic dermographism

1979 • 82 citations

SOME CLIKICAL ASPECTS OF CHOLHSTERGIC URTICARIA

1968 • 81 citations

Urticaria. An updated review

1977 • 76 citations

Cimetidine in chronic idiopathic urticaria: a randomized double-blind study

1978 • 76 citations

Ketotifen: Current Views on Its Mechanism of Action and Their Therapeutic Implications

1984 • 71 citations

Treatment of chronic idiopathic urticaria with combined HI and H2 blockers

1978 • 69 citations

Treatment of chronic urticaria with terfenadine and ranitidine

1986 • 68 citations

Cetirizine effects on objective measures of daytime sleepiness and performance.

1987 • 66 citations

Torsade de pointes ventricular tachycardia associated with astemizole overdose

1988 • 66 citations

Therapy of chronic idiopathic urticaria with nifedipine: Demonstration of beneficial effect in a double-blinded, placebo-controlled, crossover trial

1989 • 63 citations

Antihistamines, drowsiness, and psychomotor impairment: central nervous system effect of cetirizine.

1987 • 62 citations

Recent advances in dermatology-6

1984 • 60 citations

Comparative effects of loratadine and terfenadine in the treatment of chronic idiopathic urticaria.

1990 • 60 citations

Laboratory Tests in Chronic Urticaria

1980 • 58 citations

Suppression of histamine-induced pruritus by three antihistaminic drugs*1

1975 • 56 citations

Inhibitory effect of terfenadine on mediator release from human blood basophils and eosinophils

1989 • 50 citations

Antidepressant Drugs in Dermatology

1987 • 49 citations

Oxatomide

1984 • 48 citations

Urticaria

1977 • 48 citations

Double-blind comparison of terfenadine, chlorpheniramine, and placebo in the treatment of chronic idiopathic urticaria

1988 • 47 citations

Chronic urticaria: Review of nonsedating H1 antihistamines in treatment

1988 • 46 citations

Antihistaminic effect of terfenadine: A new piperidine‐type antihistamine

1982 • 45 citations

A comparison of astemizole and chlorpheniramine in dermographic urticaria

1985 • 44 citations

Effects of loratadine (SCH 29851) in suppression of histamine-induced skin wheals.

1988 • 44 citations

Treatment of chronic urticaria with PUVA or UVA plus placebo: A double-blind study

1986 • 44 citations

Absence of an effect of terfenadine on guinea pig brain histamine H1-receptors in vivo determined by receptor binding techniques.

1982 • 43 citations

The treatment of glucocorticosteroid-dependent chronic urticaria with stanozolol

1988 • 41 citations

Treatment of chronic urticaria with a beta₂‐adrenergic stimulant

1977 • 41 citations

Urticaria in Childhood: Pathogenesis and Management

1983 • 40 citations

Protease inhibitor profiles in urticaria and angio-oedema

1980 • 40 citations

Cold Urticaria: Inhibition of Cold-induced Histamine Release by Doxantrazole

1978 • 38 citations

Dermographism: reduction in weal size by chlorpheniramine and hydroxyzine

1973 • 38 citations

Effects of terfenadine, diphenhydramine, and placebo on skills performance.

1988 • 37 citations

Treatment of chronic idiopathic urticaria with terfenadine

1984 • 37 citations

Histamine release from rat peritoneal mast cells exposed to ultraviolet light

1982 • 36 citations

Clinical profile of astemizole. A survey of 50 double-blind trials.

1987 • 35 citations

Antihistamines and driving safety.

1988 • 33 citations

The effects of astemizole on histamine-induced weal and flare

1983 • 33 citations

Management of urticaria and angioedema

1980 • 31 citations

The treatment of mild to severe chronic idiopathic urticaria with astemizole: Double-blind and open trials

1986 • 30 citations

Treatment of chronic urticaria with a proteinase (kallikrein) inhibitor

2006 • 28 citations

Terfenadine and placebo compared in the treatment of chronic idiopathic urticaria: a randomised double‐blind study.

1985 • 27 citations

Histamine2 (H2)-Receptor Antagonists in the Treatment of Urticaria

1989 • 27 citations

Greater inhibition of dermographia with a combination of H1 and H2 antagonists.

1983 • 27 citations

The effect of H1 and H2 receptor antagonists on the dermographic response

1983 • 27 citations

A Case of Chronic Urticaria and Vitiligo, Associated with Thyroiditis, Treated with PUVA

1983 • 27 citations

Controlled clinical assessment of astemizole in the treatment of chronic idiopathic urticaria and angioedema

1987 • 26 citations

Double-blind comparison of astemizole and terfenadine in the treatment of chronic urticaria.

1986 • 26 citations

Ketotifen and terbutaline in urticaria.

1981 • 26 citations

Terbutaline in the treatment of chronic urticaria.

1980 • 24 citations

Terfenadine in chronic urticaria: a comparison with clemastine and placebo.

1986 • 23 citations

Successful treatment of idiopathic cold urticaria with the association of H1 and H2 antagonists: a case report.

1986 • 23 citations

Lack of effect of cimetidine in chronic-idiopathic urticaria

1983 • 22 citations

Use of a kallikrein inhibitor in the treatment of urticaria and hereditary

1969 • 22 citations

Oxatomide in the Treatment of Chronic Urticaria

1981 • 22 citations

Does Mast Cell Protection plus Mediator Antagonism Surpass the Effect of a Classic Antihistaminic in the Treatment of Chronic Urticaria?

1982 • 20 citations

Pharmacology and toxicology of nonclassical antihistamines.

1988 • 20 citations

Loratadine: A Potent, Nonsedating, and Long-Acting H¹ Antagonist

1987 • 19 citations

THE SUGGESTIVE EFFECT OF PLACEBO ON THE INTENSITY OF CHRONIC URTICARIA

1970 • 19 citations

COMPARISON OF A NEW ANTIHISTAMINE HC 20–511* WITH CYPROHEPTADINE (PERIACTIN®) IN CHRONIC URTICARIA

1977 • 18 citations

Treatment of Urticaria

1985 • 16 citations

Double-blind, placebo-controlled study of terfenadine and hydroxyzine in patients with chronic idiopathic urticaria.

1989 • 14 citations

Cetirizine, a Novel Antihistamine

1987 • 13 citations

173 The efficacy and safety of loratidine in the management of chronic idiopathic urticaria

1988 • 13 citations

Newer Non-Sedating Antihistamines Will They Replace Older Agents?

1985 • 13 citations

Bioassay of Antihistaminic Action

1978 • 11 citations

The Evaluation of Patients with Urticaria

1985 • 9 citations

Absorption, Distribution, Metabolism, and Elimination of Antihistamines

1978 • 9 citations

H₂ Blockers in Chronic Urticaria

1984 • 7 citations

Antihistamines

1986 • 7 citations

Commentary: Antihistamines and the Treatment of Urticaria

1983 • 4 citations

Comparison of efficacy and tolerability of terfenadine administered once daily versus twice daily in patients with chronic idiopathic urticaria.

1989 • 4 citations

International Symposium on Advances in Therapeutics in Dermatology

1989 • 1 citations