Immunoregulation of the Mixed Lymphocyte Reaction by Macrophage-Derived Factors: Functional and Biochemical Separation of Enhancing and Inhibitory Factors

Convenient assay for interferons

1981 • 486 citations

Regulation of the production of immune interferon and cytotoxic T lymphocytes by interleukin 2.

1981 • 477 citations

Two distinct factors are required for induction of T-cell growth

1980 • 416 citations

Characterization of lymphocyte-activating factor (LAF) produced by the macrophage cell line, P388D1. I. Enhancement of LAF production by activated T lymphocytes.

1978 • 379 citations

Production of lymphocyte-activating factor (Interleukin 1) by macrophages activated with colony-stimulating factors.

1980 • 272 citations

Characterization of Lymphocyte-Activating Factor (LAF) Produced by the Macrophage Cell Line, P388D1

1978 • 237 citations

The modulation of lymphocyte functions by molecules secreted by macrophages. I. Description and partial biochemical analysis.

1975 • 229 citations

The role of macrophages in the acute-phase response: SAA inducer is closely related to lymphocyte activating factor and endogenous pyrogen

1981 • 224 citations

Macrophage-independent activation of helper T cells. I. Production of Interleukin 2.

1980 • 219 citations

Bidirectional Amplification of Macrophage-Lymphocyte Interactions: Enhanced Lymphocyte Activation Factor Production by Activated Adherent Mouse Peritoneal Cells

1977 • 184 citations

CELL-MEDIATED IMMUNE RESPONSE IN VITRO

1972 • 180 citations

Biochemical characterization of a factor released by macrophages

1975 • 178 citations

Relationship between production and release of lymphocyte-activating factor (interleukin 1) by murine macrophages

1981 • 174 citations

Characterization of lymphocyte-activating factor (LAF) produced by a macrophage cell line, P388D1. II. Biochemical characterization of LAF induced by activated T cells and LPS.

1978 • 172 citations

T‐CELL GROWTH FACTOR‐MEDIATED T‐CELL PROLIFERATION*

1979 • 168 citations

Participation of lymphocyte activating factor (Interleukin 1) in the induction of cytotoxic T cell responses.

1980 • 157 citations

Purification and Properties of Human Lymphocyte Activating Factor (LAF)

1977 • 154 citations

An Inhibitor of Cell Proliferation Released by Cultures of Macrophages

1974 • 151 citations

Relationship of cell cycle to recovery of IL 2 activity from human mononuclear cells, human and mouse T cell lines.

1981 • 148 citations

Major changes in lymphocyte proliferation evoked by activated macrophages

1975 • 135 citations

Macrophage regulation of DNA synthesis in lymphoid cells: Effects of a soluble factor from macrophages

1973 • 125 citations

Partial Purification of Human Lymphocyte-Activating Factor (LAF) by Ultrafiltration and Electrophoretic Techniques

1977 • 124 citations

Potentiation of the T lymphocyte response to mitogens

1974 • 122 citations

Suppressor cell activity in tumor-bearing mice. I. Dualistic inhibition by suppressor T lymphocytes and macrophages.

1978 • 111 citations

Facilitation or attenuation of mixed leukocyte culture responsiveness by adherent cells

1976 • 104 citations

Physicochemical Characterization of Lymphocyte-Activating Factor (LAF)

1979 • 99 citations

Macrophage Activation of Allogeneic Lymphocyte Proliferation in the Guinea Pig Mixed Leukocyte Culture

1975 • 92 citations

Enhancement of DNA Synthesis and cAMP Content of Mouse Thymocytes by Mediator(s) Derived from Adherent Cells

1976 • 91 citations

Macrophages in the mixed leukocyte culture reaction (MLC)

1974 • 90 citations

Synthesis and Secretion of a Mitogenic Protein by Macrophages: Description of a Superinduction Phenomenon

1977 • 87 citations

Characterization of a Congenitally LPS-Resistant, Athymic Mouse Strain

1979 • 85 citations

Characterization of Lymphocyte-Activating Factor (LAF) Produced by a Macrophage Cell Line, P388D1

1978 • 85 citations

Prostaglandin synthesis in spleen cell cultures of mice injected with Corynebacterium parvum

1978 • 80 citations

Regulation of Lymphocyte-Activating Factor (LAF) Production and Secretion in P388D1 Cells: Identification of High Molecular Weight Precursors of LAF

1979 • 74 citations

Suppressor Cell Activity in Tumor-Bearing Mice

1978 • 68 citations

The Suppressive Effect of Immunization on the Proliferative Responses of Rat T Cells in Vitro

1976 • 68 citations

Physiological regulation of antigen binding to T cells: role of a soluble macrophage factor and of interferon.

1977 • 52 citations

Generation of alloreactive cytotoxic T lymphocytes: production of T cell and macrophage helper factors in addition to IL 1 and IL 2 by peritoneal cells from mice immunized to Listeria monocytogenes.

1981 • 39 citations

Macrophage regulation of the T-cell allogeneic response during tumor growth

1978 • 37 citations

Interleukin 2 is not sufficient as helper component for the activation of cytotoxic T lymphocytes but synergizes with a late helper effect that is provided by irradiated I-region-incompatible stimulator cells.

1982 • 36 citations

Cell Biology and Immunology of Leukocyte Function

1979 • 36 citations

The suppressive effect of immunization on the proliferative responses of rat T cells in vitro. II. Abrogation of antigen-induced suppression by selective cytotoxic agents.

1976 • 30 citations

Macromolecular inhibitory factor for lymphoid cells produced by mouse macrophages.

1977 • 26 citations

Suppressor cell activity in tumor-bearing mice. II. Inhibition of DNA synthesis and DNA polymerases by TBH splenic suppressor cells.

1978 • 25 citations

Potentiation of the T lymphocyte response to mitogens

1977 • 24 citations

T‐Cell Cytotoxicity and Amplification of the Cytotoxic Reaction by Macrophages

1973 • 24 citations

Two distinct lumphocyte-stimulating soluble factors (LAF) released from murine peritoneal cells. I. The cellular source and the effect of cGMP on their release.

1976 • 20 citations

Suppressor Cell Activity in Tumor-Bearing Mice

1978 • 17 citations

Regulation of T-cell mixed lymphocyte reaction reactivity: Demonstration of enhancing and inhibitory activity in tumor-bearing host macrophage supernatants

1979 • 16 citations

Reversal of macrophage-augmented MLR reactivity by tumor-induced splenic suppressor T cells and their soluble factor(s)

1979 • 13 citations

Cell-mediated cytostasis: A critical analysis of methodological problems

1979 • 10 citations

Yugoslavia changes nuclear site after protests

1979 • 4 citations

Analysis of macrophage factor inhibiting cellular DNA synthesis employing column chromatography.

1978 • 4 citations

Analysis of a macrophage factor inhibiting cellular DNA synthesis employing column chromatography

1980 • 3 citations

Macrophage-derived factor regulation in normal and tumor- -bearing hosts. Abstr.

1982 • 2 citations