The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function

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Endosomal transport function in yeast requires a novel AAA-type ATPase, Vps4p

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The AAA team: related ATPases with diverse functions

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1994 • 395 citations

VPS27 controls vacuolar and endocytic traffic through a prevacuolar compartment in Saccharomyces cerevisiae.

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Protein Sorting in Saccharomyces cerevisiae: Isolation of Mutants Defective in the Delivery and Processing of Multiple Vacuolar Hydrolases

1988 • 339 citations

A 200‐amino acid ATPase module in search of a basic function

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GTPase activity of Rab5 acts as a timer for endocytic membrane fusion

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Multilamellar endosome-like compartment accumulates in the yeast vps28 vacuolar protein sorting mutant.

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An abundant and ubiquitous homo-oligomeric ring-shaped ATPase particle related to the putative vesicle fusion proteins Sec18p and NSF.

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Dynamin Self-assembly Stimulates Its GTPase Activity

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1992 • 185 citations

Hrs, a Tyrosine Kinase Substrate with a Conserved Double Zinc Finger Domain, Is Localized to the Cytoplasmic Surface of Early Endosomes

1997 • 161 citations

The cytoplasmic tail domain of the vacuolar protein sorting receptor Vps10p and a subset of VPS gene products regulate receptor stability, function, and localization.

1995 • 157 citations

A novel Sec18p/NSF-dependent complex required for Golgi-to-endosome transport in yeast.

1997 • 153 citations

Each Domain of the N-Ethylmaleimide-sensitive Fusion Protein Contributes to Its Transport Activity

1995 • 138 citations

Inhibition of Endosome Function in CHO Cells Bearing a Temperature-sensitive Defect in the Coatomer (COPI) Component ε-COP

1997 • 138 citations

Transport through the yeast endocytic pathway occurs through morphologically distinct compartments and requires an active secretory pathway and Sec18p/N-ethylmaleimide-sensitive fusion protein.

1997 • 108 citations

The VPS16 gene product associates with a sedimentable protein complex and is essential for vacuolar protein sorting in yeast.

1993 • 103 citations

Rab7 Regulates Transport from Early to Late Endocytic Compartments in Xenopus Oocytes

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Multiple N-ethylmaleimide-sensitive components are required for endosomal vesicle fusion.

1994 • 85 citations

A Yeast Protein Related to a Mammalian Ras-Binding Protein, Vps9p, Is Required for Localization of Vacuolar Proteins

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Mutational Analysis of Csc1/Vps4p: Involvement of Endosome in Regulation of Autophagy in Yeast.

1997 • 60 citations

The ATPase activity of purified CDC48p from Saccharomyces cerevisiae shows complex dependence on ATP-, ADP-, and NADH-concentrations and is completely inhibited by NEM

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The VPS4 gene is involved in protein transport out of a yeast pre-vacuolar endosome-like compartment

1997 • 48 citations

Identification of a novel mammalian member of the NSF/CDC48p/Pas1p/TBP‐1 family through heterologous expression in yeast

1994 • 46 citations

NSF is required for transport from early to late endosomes

1997 • 43 citations

Molecular and genetic analysis of the SNF7 gene in Saccharomyces cerevisiae.

1993 • 39 citations

Regulatory role of major tyrosine autophosphorylation site of kinase domain of c-Met receptor (scatter factor/hepatocyte growth factor receptor).

1994 • 24 citations