Powers and Pitfalls in Sequence Analysis: The 70% Hurdle: Table 1.

Protein secondary structure prediction based on position-specific scoring matrices 1 1Edited by G. Von Heijne

1999 • 5,382 citations

Detecting Protein Function and Protein-Protein Interactions from Genome Sequences

1999 • 1,661 citations

A comparison of selected mRNA and protein abundances in human liver

1997 • 1,274 citations

The DNA sequence of human chromosome 22

1999 • 1,167 citations

Protein interaction maps for complete genomes based on gene fusion events

1999 • 1,090 citations

Principles governing amino acid composition of integral membrane proteins: application to topology prediction 1 1Edited by J. Thornton

1998 • 1,085 citations

A combined algorithm for genome-wide prediction of protein function

1999 • 921 citations

Machine learning approaches for the prediction of signal peptides and other protein sorting signals

1999 • 610 citations

[30] Prediction and analysis of coiled-coil structures

1996 • 574 citations

Predicting Pol II Promoter Sequences using Transcription Factor Binding Sites

1995 • 446 citations

Prediction of Potential GPI-modification Sites in Proprotein Sequences

1999 • 435 citations

Predicting function: from genes to genomes and back 1 1Edited by P. E. Wright

1998 • 422 citations

Errors in genome annotation

1999 • 371 citations

The Recruitment of Crystallins: New Functions Precede Gene Duplication

1991 • 335 citations

Predicting functions from protein sequences—where are the bottlenecks?

1998 • 311 citations

Reliable identification of large numbers of candidate SNPs from public EST data

1999 • 248 citations

Epitope Mapping by Label-Free Biomolecular Interaction Analysis

1996 • 223 citations

Genome evolution

2000 • 184 citations

Adaptation of protein surfaces to subcellular location 1 1Edited by F. E. Cohen

1998 • 165 citations

Advances in structural genomics

1999 • 136 citations

Alternative splicing of human genes: more the rule than the exception?

1999 • 125 citations

Benchmarking PSI-BLAST in genome annotation 1 1Edited by G. von Heijne

1999 • 107 citations

Go hunting in sequence databases but watch out for the traps

1996 • 105 citations

Protein annotation: detective work for function prediction

1998 • 74 citations

The challenges of genome sequence annotation or “The devil is in the details”

1997 • 53 citations

Prediction of protein hydration sites from sequence by modular neural networks

1998 • 44 citations

Keeping Genome Databases Clean and Up to Date

1999 • 39 citations

Regulatory RNA

1998 • 5 citations