Selective involvement of kappa opioid and phencyclidine receptors in the analgesic and motor effects of dynorphin-A-(1–13)-Tyr-Leu-Phe-Asn-Gly-Pro

Dynorphin-(1-13), an extraordinarily potent opioid peptide.

1979 • 852 citations

Altered patterns of dynorphin immunoreactivity suggest mossy fiber reorganization in human hippocampal epilepsy

1990 • 615 citations

Nor-binaltorphimine, a highly selective kappa-opioid antagonist in analgesic and receptor binding assays.

1988 • 399 citations

Excitatory amino acid receptors, neural membrane phospholipid metabolism and neurological disorders

1991 • 286 citations

Nonopiate Effects of Dynorphin and Des-Tyr-Dynorphin

1982 • 235 citations

Sites for Antagonism on the N-Methyl-D-Aspartate Receptor Channel Complex

1991 • 216 citations

Dextromethorphan and neuromodulation: old drug coughs up new activities

1989 • 205 citations

Selective blockade of N-methyl-D-aspartate (NMDA)-induced convulsions by NMDA antagonists and putative glycine antagonists: relationship with phencyclidine-like behavioral effects.

1990 • 198 citations

The novel anticonvulsant MK-801: a potent and specific ligand of the brain phencyclidine/gd-receptor

1987 • 197 citations

Possible regulatory role of dynorphin on morphine- and beta-endorphin-induced analgesia.

1981 • 169 citations

Antinociception and paralysis induced by intrathecal dynorphin A.

1985 • 164 citations

Seizures induce dramatic and distinctly different changes in enkephalin, dynorphin, and CCK immunoreactivities in mouse hippocampal mossy fibers

1988 • 157 citations

Dynorphin A and related peptides administered intrathecally in the rat: a search for putative kappa opiate receptor activity.

1986 • 157 citations

[3H]TCP: a new tool with high affinity for the PCP receptor in rat brain

1983 • 156 citations

Dynorphin interaction at the κ-opiate site

1981 • 111 citations

A novel interaction between dynorphin(1–13) and an N-methyl-d-aspartate site

1988 • 96 citations

A specific acylating agent for the [³H]phencyclidine receptors in rat brain

1985 • 80 citations

Competitive and non-competitive NMDA antagonists limit dynorphin A-induced rat hindlimb paralysis

1990 • 80 citations

Binding of sigma-ligands to C57BL/6 mouse brain membranes: effects of monoamine oxidase inhibitors and subcellular distribution studies suggest the existence of sigma-receptor subtypes.

1991 • 72 citations

Intrathecal dynorphin (1–13) results in an irreversible loss of the tail-flick reflex in rats

1987 • 65 citations

Intrathecal dynorphin A1–13 and dynorphin A3–13 reduce rat spinal cord blood flow by non-opioid mechanisms

1987 • 64 citations

Analgesic effects of dynorphin-A and morphine in mice

1985 • 47 citations

A sample size correction for Pearson chi-square in 2 × 2 contingency tables.

1982 • 45 citations

Dynorphin A-( 1-13)-Tyr14Leu15-Phe16-Asn17-Gly18-Pro19: a potent and selective κ opioid peptide

1991 • 12 citations