G Protein betagamma Complexes in Circumvallate Taste Cells Involved in Bitter Transduction

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

The Many Faces of G Protein Signaling

1998 • 1,137 citations

G PROTEIN βγ SUBUNITS

1997 • 834 citations

Role of βγ Subunits of G Proteins in Targeting the β-Adrenergic Receptor Kinase to Membrane-Bound Receptors

1992 • 703 citations

Putative Mammalian Taste Receptors

1999 • 676 citations

Gustducin is a taste-cell-specific G protein closely related to the transducins

1992 • 662 citations

Transduction of bitter and sweet taste by gustducin

1996 • 658 citations

Isozyme-selective stimulation of phospholipase C-β2 by G protein βγ-subunits

1992 • 630 citations

Subunits βγ of heterotrimeric G protein activate β2 isoform of phospholipase C

1992 • 506 citations

The binding site for the beta gamma subunits of heterotrimeric G proteins on the beta-adrenergic receptor kinase.

1993 • 467 citations

Gγ13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatonium

1999 • 332 citations

Mechanisms of taste transduction

1996 • 258 citations

A Bitter Substance Induces a Rise in Intracellular Calcium in a Subpopulation of Rat Taste Cells

1988 • 221 citations

Changes in IP3 and cytosolic Ca2+ in response to sugars and non‐sugar sweeteners in transduction of sweet taste in the rat.

1996 • 206 citations

Coupling of bitter receptor to phosphodiesterase through transducin in taste receptor cells

1995 • 198 citations

Identification of a phospholipase C β subtype in rat taste cells

1998 • 192 citations

Activation of phospholipase C beta 2 by the alpha and beta gamma subunits of trimeric GTP-binding protein.

1993 • 186 citations

Differential Expression of RNA and Protein of the Three Pore-forming Subunits of the Amiloride-sensitive Epithelial Sodium Channel in Taste Buds of the Rat

1999 • 184 citations

Receptor and Gβγ isoform-specific interactions with G protein-coupled receptor kinases

1997 • 184 citations

Cloning, sequencing, expression, and Gq-independent activation of phospholipase C-beta 2.

1992 • 176 citations

The G-Protein βγ Complex

1998 • 173 citations

A cyclic–nucleotide–suppressible conductance activated by transducin in taste cells

1995 • 121 citations

Localization of phosphatidylinositol signaling components in rat taste cells: role in bitter taste transduction.

1990 • 120 citations

Dual second-messenger pathways in olfactory transduction

1995 • 100 citations

Rapid kinetics of second messenger production in bitter taste

1996 • 94 citations

Generation of Cyclic AMP in Taste Buds of the Rat Circumvallate Papilla in Response to Sucrose

1991 • 82 citations

Identification of a phospholipase C beta2 region that interacts with Gbeta-gamma.

1996 • 80 citations

Identification of a Structural Element in Phospholipase C β2 That Interacts with G Protein βγ Subunits

1998 • 79 citations

Structural and Mechanistic Features of Phospholipases C: Effectors of Inositol Phospholipid-Mediated Signal Transduction

1997 • 43 citations

Transduction for Sweet Taste of Saccharin May Involve Both Inositol 1,4,5-Trisphosphate and cAMP Pathways in the Fungiform Taste Buds in C57BL Mice

1999 • 34 citations

Single-cell cDNA-PCR: removal of contaminating genomic DNA from total RNA using immobilized DNase I.

1992 • 32 citations

A rapid method of collecting taste tissue from rats and mice

1989 • 11 citations

[37] Design of oligonucleotide probes for molecular cloning of β and γ subunits

1994 • 6 citations