Equol induces apoptosis through cytochrome c-mediated caspases cascade in human breast cancer MDA-MB-453 cells

Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis

1998 • 4,383 citations

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

1994 • 2,575 citations

Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy

2006 • 2,180 citations

Flavonoids: Promising anticancer agents

2003 • 1,132 citations

Caspase function in programmed cell death

2006 • 817 citations

Effects of dietary flavonoids on apoptotic pathways related to cancer chemoprevention

2007 • 597 citations

Soy Isoflavones and Cancer Prevention

2003 • 370 citations

Antioxidant Activity of Isoflavones and Their Major Metabolites Using Different in Vitro Assays

2006 • 313 citations

Recent advances in understanding the cell death pathways activated by anticancer therapy

2005 • 308 citations

Mdm2 inhibitor Nutlin-3a induces p53-mediated apoptosis by transcription-dependent and transcription-independent mechanisms and may overcome Atm-mediated resistance to fludarabine in chronic lymphocytic leukemia

2006 • 238 citations

Differential effects of dietary phyto-oestrogens daidzein and equol on human breast cancer MCF-7 cells

1997 • 189 citations

Caspases and cancer: mechanisms of inactivation and new treatment modalities.

2004 • 163 citations

Effects of Soy Phytoestrogens Genistein and Daidzein on Breast Cancer Growth

2001 • 162 citations

The phytoestrogen equol increases nitric oxide availability by inhibiting superoxide production: an antioxidant mechanism for cell-mediated LDL modification

2003 • 134 citations

An Overview of the Health Effects of Isoflavones with an Emphasis on Prostate Cancer Risk and Prostate-Specific Antigen Levels

2006 • 132 citations

Down-Regulation of Osteoclast Differentiation by Daidzein via Caspase 3

2002 • 104 citations

Quercetin Induces Necrosis and Apoptosis in SCC-9 Oral Cancer Cells

2005 • 98 citations

Effects of Soy Isoflavones on Apoptosis Induction and G2-M Arrest in Human Hepatoma Cells Involvement of Caspase-3 Activation, Bcl-2 and Bcl-XL Downregulation, and Cdc2 Kinase Activity

2003 • 97 citations

Neuronal apoptosis resulting from high doses of the isoflavone genistein: role for calcium and p42/44 mitogen-activated protein kinase.

2001 • 82 citations

Inhibitory effect of genistein and daidzein on ovarian cancer cell growth.

2004 • 76 citations

Biphasic effect of daidzein on cell growth of human colon cancer cells

2004 • 65 citations

Daidzein-Sulfate Metabolites Affect Transcriptional and Antiproliferative Activities of Estrogen Receptor-β in Cultured Human Cancer Cells

2005 • 65 citations

Equol: A Comparison of the Effects of the Racemic Compound With That of the Purified S-Enantiomer on the Growth, Invasion, and DNA Integrity of Breast and Prostate Cells In Vitro

2006 • 61 citations

Prostatic fluid concentrations of isoflavonoids in soy consumers are sufficient to inhibit growth of benign and malignant prostatic epithelial cells in vitro

2005 • 57 citations

A review of the animal models used to investigate the health benefits of soy isoflavones.

2006 • 37 citations

AReview of the Animal Models Used to Investigate the Health Benefits of Soy Isoflavones

2006 • 28 citations

Equol induced apoptosis via cell cycle arrest in human breast cancer MDA-MB-453 but not MCF-7 cells

2008 • 21 citations

Down-regulation of increased signal transduction capacity in human cancer cells

2005 • 16 citations

Cancer gene therapy: strategies and clinical trials.

2005 • 8 citations

Equol induced the apoptosis via cell cycle arrest in MDA‐MB‐453 but not in MCF‐7 cells

2008 • 4 citations