Reactive oxygen intermediates and liver injury

Oxygen-Derived Free Radicals in Postischemic Tissue Injury

1985 • 5,488 citations

Oxygen toxicity, oxygen radicals, transition metals and disease

1984 • 5,301 citations

Role of oxygen-derived free radicals and metabolites in leukocyte-dependent inflammatory reactions.

1982 • 1,241 citations

Conversion of xanthine dehydrogenase to oxidase in ischemic rat tissues.

1987 • 350 citations

Free radicals in liver injury

1987 • 338 citations

Ferric iron and superoxide ions are required for the killing of cultured hepatocytes by hydrogen peroxide. Evidence for the participation of hydroxyl radicals formed by an iron-catalyzed Haber-Weiss reaction.

1985 • 300 citations

Role of free radicals in ischemia-reperfusion injury to the liver.

1986 • 253 citations

INFLUENCE OF OXYGEN-DERIVED FREE RADICAL SCAVENGERS ON ISCHEMIC LIVERS

1985 • 230 citations

Oxygen-derived free radicals promote hepatic injury in the rat

1985 • 207 citations

Intracellular localization of the copper-zinc and manganese superoxide dismutases in rat liver parenchymal cells.

1986 • 195 citations

Mechanisms of the killing of cultured hepatocytes by hydrogen peroxide

1984 • 172 citations

Degradation of human glomerular basement membrane by stimulated neutrophils. Activation of a metalloproteinase(s) by reactive oxygen metabolites.

1987 • 147 citations

Beneficial effect of allopurinol in liver ischemia.

1985 • 142 citations

Arrangement of the respiratory burst oxidase in the plasma membrane of the neutrophil.

1981 • 133 citations

Increased microsomal oxidation of hydroxyl radical scavenging agents and ethanol after chronic consumption of ethanol

1983 • 105 citations

Oxygen-mediated cell injury in the killing of cultured hepatocytes by acetaminophen

1985 • 93 citations

Corynebacterium parvum-elicited hepatic macrophages demonstrate enhanced respiratory burst activity compared with resident kupffer cells in the rat

1986 • 93 citations

COULD SUPEROXIDE CAUSE CIRRHOSIS?

1982 • 77 citations

Lysosomal origin of the ferric iron required for cell killing by hydrogen peroxide

1985 • 63 citations

Microsomal Generation of Hydroxyl Radicals: Its Role in Microsomal Ethanol Oxidizing System (MEOS) Activity and Requirement for Irona

1987 • 31 citations

Xenobiotics, drug metabolism, and liver injury.

1987 • 15 citations

Deleted Work

1955 • 0 citations