The regulation and expression of MHC class I genes

NF-κB: A pleiotropic mediator of inducible and tissue-specific gene control

1989 • 1,622 citations

Cyclic AMP and the induction of eukaryotic gene transcription.

1988 • 1,041 citations

Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes

1989 • 970 citations

Human CCAAT-binding proteins have heterologous subunits

1988 • 712 citations

Molecular cloning of an enhancer binding protein:Isolation by screening of an expression library with a recognition site DNA

1988 • 677 citations

Inducible expression of H–2 and Ia antigens on brain cells

1984 • 656 citations

Expression of class I major histocompatibility antigens switched off by highly oncogenic adenovirus 12 in transformed rat cells

1983 • 586 citations

The involvement of NF-κB in β-interferon gene regulation reveals its role as widely inducible mediator of signal transduction

1989 • 494 citations

THE DETAILED DISTRIBUTION OF HLA-A, B, C ANTIGENS IN NORMAL HUMAN ORGANS

1984 • 410 citations

Widespread and selective induction of major histocompatibility complex-determined antigens in vivo by gamma interferon.

1985 • 397 citations

Detailed analysis of the mouse H-2Kb promoter: Enhancer-like sequences and their role in the regulation of class I gene expression

1986 • 395 citations

Tumorigenicity of cells transformed by adenovirus type 12 by evasion of T-cell immunity

1983 • 353 citations

Double-stranded RNA activates binding of NF-kappa B to an inducible element in the human beta-interferon promoter.

1989 • 317 citations

Interferon-activated genes

1986 • 301 citations

TNF stimulates expression of mouse MHC class I genes by inducing an NF kappa B-like enhancer binding activity which displaces constitutive factors.

1989 • 275 citations

Interferon response sequence potentiates activity of an enhancer in the promoter region of a mouse H–2 gene

1986 • 252 citations

A DNA-binding protein containing two widely separated zinc finger motifs that recognize the same DNA sequence.

1990 • 249 citations

Tumor necrosis factor enhances HLA-A,B,C and HLA-DR gene expression in human tumor cells.

1987 • 248 citations

Binding of a nuclear factor to a regulatory sequence in the promoter of the mouse H-2Kb class I major histocompatibility gene.

1987 • 244 citations

Regulation of Cytokine Gene Expression

1988 • 234 citations

Qa-1 restricted recognition of foreign antigen by a γδ T-cell hybridoma

1989 • 233 citations

Structure and specificity of T cell receptor gamma/delta on major histocompatibility complex antigen-specific CD3+, CD4-, CD8- T lymphocytes.

1988 • 227 citations

Role of the Major Histocompatibility Complex Class I Antigens in Tumor Growth and Metastasis

1988 • 201 citations

Purification of KBF1, a common factor binding to both H-2 and beta 2-microglobulin enhancers.

1987 • 184 citations

Three distinct classes of regulatory cytokines control endothelial cell MHC antigen expression. Interactions with immune gamma interferon differentiate the effects of tumor necrosis factor and lymphotoxin from those of leukocyte alpha and fibroblast beta interferons.

1988 • 142 citations

Regulation of Gene Expression by Interferons: Control of H-2 Promoter Responses

1988 • 136 citations

Involvement of acis-element that binds an H2TF-l/NFxB like factor(s) in the virus-induced interferon-β gene expression

1989 • 118 citations

A gamma-interferon-induced factor that binds the interferon response sequence of the MHC class I gene, H-2Kb.

1989 • 113 citations

Interferons increase transcription of a major histocompatibility class I gene via a 5' interferon consensus sequence.

1987 • 105 citations

MHC-Antigen Interaction: What Does the T Cell Receptor See?

1989 • 102 citations

Analysis of Qa-2 Antigen Expression by Preimplantation Mouse Embryos: Possible Relationship to the Preimplantation-Embryo-Development (Ped) Gene Product1

1987 • 97 citations

T cell maturation: thymocyte and thymus migrant subpopulations defined with monoclonal antibodies to MHC region antigens.

1980 • 90 citations

Structural and functional dissection of an MHC class I antigen-binding adenovirus glycoprotein.

1986 • 87 citations

Developmental and tissue-specific expression of nuclear proteins that bind the regulatory element of the major histocompatibility complex class I gene.

1989 • 84 citations

Binding of multiple nuclear factors to the 5' upstream regulatory element of the murine major histocompatibility class I gene.

1987 • 81 citations

A low polymorphic mouse H-2 class I gene from the Tla complex is expressed in a broad variety of cell types.

1987 • 75 citations

Induction of assembly of MHC class I heavy chains with beta 2microglobulin by interferon-gamma.

1989 • 72 citations

Two purified factors bind to the same sequence in the enhancer of mouse MHC class I genes: one of them is a positive regulator induced upon differentiation of teratocarcinoma cells

1989 • 65 citations

Identification of negative and positive regulatory elements associated with a class I major histocompatibility complex gene.

1988 • 65 citations

The SV40 TC-II(kappa B) and the related H-2Kb enhansons exhibit different cell type specific and inducible proto-enhancer activities, but the SV40 core sequence and the AP-2 binding site have no enhanson properties.

1989 • 63 citations

Autogenous production of interferon-beta switches on HLA genes during differentiation of histiocytic lymphoma U937 cells.

1984 • 61 citations

The SV40 TC-II(kappa B) enhanson binds ubiquitous and cell type specifically inducible nuclear proteins from lymphoid and non-lymphoid cell lines.

1989 • 61 citations

Asynchronous regulation of mouse H-2D and beta-2 microglobulin RNA transcripts

1985 • 60 citations

Regulation of Qa-1 expression and determinant modification by an H-2D-linked gene, Qdm

1988 • 59 citations

Organization and structure of the Qa genes of the major histocompatibility complex of the C3H mouse: implications for Qa function and class I evolution.

1989 • 59 citations

Increased MHC H–2K gene transcription in cultured mouse embryo cells after adenovirus infection

1985 • 56 citations

Qa-2 expression in the adult murine thymus. A unique marker for a mature thymic subset.

1989 • 53 citations

Identification of sequences responsible for positive and negative regulation by E1A in the promoter of H-2Kbm1 class I MHC gene.

1990 • 52 citations

An antigenic difference between cells forming early and late haematopoietic spleen colonies (CFU-S)

1984 • 50 citations

Induction of major histocompatibility class I antigens by interferons in undifferentiated F9 cells

1987 • 44 citations

In vivo induction of H‐2K/D antigens by recombinant interferon‐γ

1986 • 41 citations

IFN-mediated differential regulation of the expression of HLA-B7 and HLA-A3 class I genes.

1989 • 40 citations

Tla-region genes and their products

1987 • 36 citations

Nuclear proteins binding to an enhancer element of the major histocompatibility class I promoter: Differences between highly oncogenic and nononcogenic adenovirus-transformed rat cells

1989 • 29 citations

Qa ANTIGENS AND THEIR DIFFERENTIAL DISTRIBUTION ON LYMPHOID, MYELOID AND STEM CELLS

1984 • 24 citations

Modulation of major histocompatibility complex (MHC) class I genes in adenovirus 12 transformed cells: interferon-gamma increases class I expression by a mechanism that circumvents E1A induced-repression and tumor necrosis factor enhances the effect of interferon-gamma.

1989 • 20 citations

Regulation of HLA class I transcription in T cells.

1989 • 19 citations

Tissue-specific expression of the mouse Q10 H-2 class-I gene during embryogenesis

1987 • 18 citations

Widespread transcription of a Qa region gene in adult mice.

1987 • 16 citations

Mechanism of induction of class I major histocompatibility antigen expression by murine leukemia virus

1988 • 14 citations

Structure and expression of polypeptides encoded in the mouseQa region

1987 • 13 citations

Study of Functional Lymphocyte Populations with Heterologous Antisera

1971 • 9 citations

Analysis of structure/function relationships among major histocompatibility complex class I antigens

1987 • 2 citations