Does thrombolytic therapy reduce infarct size?

Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. ISIS-2 (Second International Study of Infarct Survival) Collaborative Group.

1988 • 2,740 citations

EFFECTIVENESS OF INTRAVENOUS THROMBOLYTIC TREATMENT IN ACUTE MYOCARDIAL INFARCTION

1986 • 2,315 citations

Plaque fissuring--the cause of acute myocardial infarction, sudden ischaemic death, and crescendo angina.

1985 • 2,003 citations

The wavefront phenomenon of ischemic cell death. 1. Myocardial infarct size vs duration of coronary occlusion in dogs.

1977 • 1,927 citations

Angiographic progression of coronary artery disease and the development of myocardial infarction

1988 • 1,450 citations

Para-aminosalicylic acid in tuberculosis; early results of clinical trials.

1947 • 797 citations

A Prospective Trial of Intravenous Streptokinase in Acute Myocardial Infarction (I.S.A.M.)

1986 • 705 citations

Effect of Intravenous Streptokinase on Left Ventricular Function and Early Survival after Acute Myocardial Infarction

1987 • 628 citations

Intravenous and intracoronary fibrinolytic therapy in acute myocardial infarction: Overview of results on mortality, reinfarction and side-effects from 33 randomized controlled trials

1985 • 578 citations

LONG-TERM EFFECTS OF INTRAVENOUS THROMBOLYSIS IN ACUTE MYOCARDIAL INFARCTION: FINAL REPORT OF THE GISSI STUDY

1987 • 521 citations

Early thrombolysis in acute myocardial infarction: Limitation of infarct size and improved survival

1986 • 510 citations

Coronary Arteriographic Findings Soon after Non-Q-Wave Myocardial Infarction

1986 • 424 citations

Coronary thrombolysis and myocardial salvage by tissue plasminogen activator given up to 4 hours after onset of myocardial infarction

1988 • 275 citations

The Reduction of Infarct Size — An Idea Whose Time (For Testing) Has Come

1974 • 191 citations

Global and regional left ventricular function and tomographic radionuclide perfusion: the Western Washington Intracoronary Streptokinase In Myocardial Infarction Trial.

1984 • 156 citations

Medicine and the Law

1963 • 143 citations

The “border zone” in evolving myocardial infarction: Controversy or confusion?

1981 • 90 citations

Limitations of myocardial revascularization in restoration of regional contraction abnormalities produced by coronary occlusion

1974 • 87 citations

Acute non-Q wave myocardial infarction associated with early ST segment elevation: Evidence for spontaneous coronary reperfusion and implications for thrombolytic trials

1987 • 85 citations

Myocardial revascularization after acute infarction

1975 • 75 citations

THERAPEUTIC TRIALS IN CORONARY THROMBOSIS SHOULD MEASURE LEFT VENTRICULAR FUNCTION AS PRIMARY END-POINT OF TREATMENT

1988 • 47 citations

Collateral blood supply to the myocardium at risk in human myocardial infarction: A quantitative postmortem assessment

1988 • 40 citations

LOOKING BACK, SEEING AHEAD

1988 • 36 citations

Natural defense mechanisms during ischemia

1983 • 18 citations

Cited By (0)

Loading...