Anti-depressant action of melatonin in chronic forced swimming-induced behavioral despair in mice, role of peripheral benzodiazepine receptor modulation

Behavioral despair in mice: a primary screening test for antidepressants.

1977 • 3,241 citations

Pineal Melatonin: Cell Biology of Its Synthesis and of Its Physiological Interactions*

1991 • 2,190 citations

Characterization of peripheral-type benzodiazepine binding sites in brain using [3H]Ro 5-4864.

1982 • 384 citations

Circadian timekeeping in BALB/c and C57BL/6 inbred mouse strains

1990 • 308 citations

Natural melatonin `knockdown' in C57BL/6J mice: rare mechanism truncates serotonin N-acetyltransferase

1998 • 280 citations

Role of the pineal gland in immunity: II. Melatonin enhances the antibody response via an opiatergic mechanism.

1987 • 213 citations

Melatonin Effects on Behavior: Possible Mediation by the Central GABAergic System

1996 • 200 citations

Differential anxiolytic effects of neurosteroids in the mirrored chamber behavior test in mice

1997 • 164 citations

Minireview: Cell protective role of melatonin in the brain

1995 • 147 citations

Sigma (σ1) receptor mediated antidepressant-like effects of neurosteroids in the Porsolt forced swim test

1998 • 138 citations

Melatonin increases in vivo GABA accumulation in rat hypothalamus, cerebellum, cerebral cortex and pineal gland

1986 • 132 citations

Stimulation of Brain Pregnenolone Synthesis by Mitochondrial Diazepam Binding Inhibitor Receptor Ligands In Vivo

1993 • 129 citations

The potential use of GABA agonists in psychiatric disorders: Evidence from studies with progabide in animal models and clinical trials1

1983 • 129 citations

Inhibition of diazepam binding by tryptophan derivatives including melatonin and its brain metabolite N-acetyl-5-methoxy kynurenamine

1981 • 91 citations

Parallel changes in the sensitivity of γ-aminobutyric acid and noradrenergic receptors following chronic administration of antidepressant and GABAergic drugs

1985 • 85 citations

Antidepressant-like activity of the melatonin receptor antagonist, luzindole (N-0774), in the mouse behavioral despair test

1990 • 73 citations

Hypnotic and hypothermic effects of melatonin on daytime sleep in humans: lack of antagonism by flumazenil

1996 • 69 citations

Melatonin enhancement of [3H]-γ-aminobutyric acid and [3H]muscimol binding in rat brain

1988 • 68 citations

Effects of melatonin receptor ligands on swim test immobility

1998 • 66 citations

Participation of mitochondrial diazepam binding inhibitor receptors in the anticonflict, antineophobic and anticonvulsant action of 2-aryl-3-indoleacetamide and imidazopyridine derivatives.

1993 • 55 citations

Reversal of morphine tolerance and dependence by melatonin: possible role of central and peripheral benzodiazepine receptors

1999 • 53 citations

Peripheral-type benzodiazepine receptors: a second site of action for benzodiazepines.

1991 • 50 citations

GABA and mood disorders

2003 • 48 citations

Central nervous system depressant activities of melatonin in rats and mice.

1998 • 44 citations

Central-type benzodiazepine receptors mediate the antidopaminergic effect of clonazepam and melatonin in 6-hydroxydopamine lesioned rats: involvement of a GABAergic mechanism.

1995 • 40 citations

Allosteric modulation of t-[35S]butylbicyclophosphorothionate binding in rat brain by melatonin

1990 • 33 citations

[GABA and mood disorders].

1987 • 29 citations

GABA-mediated modification of despair behavior in mice

1989 • 27 citations

Intracerebroventricular injection of naloxone blocks melatonin-dependent brain [3H]flunitrazepam binding

1993 • 26 citations

Sedative potency and 2-[125I]iodomelatonin binding affinity of melatonin analogues

1995 • 20 citations

PK 11195 blockade of benzodiazepine‐induced inhibition of forskolin‐stimulated adenylate cyclase activity in the striatum

1996 • 16 citations

Influence of the Behaviorally Active Peptides ACTH<sub>1–10</sub>, and ACTH<sub>4–10</sub> on the Melatonin Modulation of <sup>3</sup>H-Flunitrazepam Receptor Binding in the Rat Cerebral Cortex

1994 • 15 citations