Behavioral Assessment of the Senescence-accelerated Mouse (SAM P8 and R1)

Validation of open : closed arm entries in an elevated plus-maze as a measure of anxiety in the rat

1985 • 5,596 citations

The Neuropsychology of Memory

1984 • 2,129 citations

Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus-maze: A novel test of anxiety in the rat

1986 • 1,509 citations

A new murine model of accelerated senescence

1981 • 855 citations

Neuropsychology of Memory

1992 • 625 citations

Age-related changes in learning and memory in the senescence-accelerated mouse (SAM)

1986 • 376 citations

Senescence‐Accelerated Mouse (SAM): A Novel Murine Model of Accelerated Senescence

1991 • 361 citations

Age-related spatial reference and working memory deficits assessed in the water maze

1995 • 314 citations

Effects of intermittent feeding upon body weight and lifespan in inbred mice: interaction of genotype and age

1990 • 266 citations

Age-related deterioration of ability of acquisition in memory and learning in senescence accelerated mouse: SAM-P/8 as an animal model of disturbances in recent memory

1988 • 243 citations

Grading score system: A method for evaluation of the degree of senescence in Senescence Accelerated Mouse (SAM)

1984 • 215 citations

Characteristics of age-related behavioral changes in senescence-accelerated mouse SAMP8 and SAMP10

1997 • 198 citations

Human nerve growth factor improves spatial memory in aged but not in young rats

1994 • 193 citations

Pathobiology of the senescence-accelerated mouse (SAM)

1997 • 185 citations

The neurology of aging

1983 • 135 citations

Is RO 15-4513 a specific alcohol antagonist?

1987 • 124 citations

Age-related changes in footshock avoidance acquisition and retention in senescence accelerated mouse (SAM)

1993 • 122 citations

Spontaneous Spongy Degeneration of the Brain Stem in SAM-P/8 Mice, a Newly Developed Memory-Deficient Strain

1989 • 120 citations

Early Onset of Age-Related Impairment of Aversive and Appetitive Learning in the SAM-P/8 Mouse

1992 • 111 citations

The SAM Model of Senescence

1994 • 111 citations

Behavioral characteristics of the SAM-P/8 strain in Sidman active avoidance task

1989 • 107 citations

Senescence-accelerated mouse (SAM): Age-related reduced anxiety-like behavior in the SAM-P/8 strain

1992 • 93 citations

Murine models of brain aging and age-related neurodegenerative diseases

1997 • 93 citations

Variable-interval probe test as a tool for repeated measurements of spatial memory in the water maze.

1993 • 86 citations

Variable-interval probe test as a tool for repeated measurements of spatial memory in the water maze.

1993 • 81 citations

Periodic acid-Schiff (PAS)-positive, granular structures increase in the brain of senescence accelerated mouse (SAM)

1986 • 80 citations

Senescence-Accelerated Mouse (SAM). A novel murine model of aging

1994 • 79 citations

Biochemical changes related to aging in the senescence-accelerated mouse

1989 • 76 citations

Central determinants of age-related declines in motor function.

1988 • 71 citations

Senescence-Accelerated Mouse(SAM). With Special Reference to Age-associated Pathologies and Their Modulation.

1996 • 51 citations

Ligand-binding characteristics of [3H]QNB, [3H]prazosin, [3H]rauwolscine, [3H]TCP and [3H]nitrendipine to cerebral cortical and hippocampal membranes of senescence accelerated mouse

1989 • 46 citations

Age-related changes in radial-arm maze learning and basal forebrain cholinergic systems in senescence accelerated mice (SAM)

1992 • 43 citations

Motor Performance Variability during Aging in Rodents Assessment of Reliability and Validity of Individual Differences

1988 • 36 citations

Neuropsychological features of memory disorders in Alzheimer disease.

1994 • 33 citations

Similarities in the age-related hippocampal deposition of periodic acid-Schiff-positive granules in the senescence-accelerated mouse (SAM P8) and C57BL/6 mouse strains

1996 • 30 citations

Individual differences in aging: behavioral and neural analyses.

1991 • 21 citations

GRADING SCORE SYSTEM - A METHOD OF EVALUATION OF THE DEGREE OF SENESCENCE IN SENESCENCE-ACCELERATED MOUSE (SAM)

1994 • 14 citations

Utilization of the Rat as a Model of Mammalian Aging: Impact of Pathology on Behavior

1996 • 10 citations

Relationship of hematological variables to learning performance in aged Fischer-344 rats

1995 • 10 citations

Genetic analysis and clinical application in polygenic diseases. Senile dementia of Alzheimer type.

1999 • 10 citations

Characteristics of age-related behavioral changes in senescence-accelerated mouse (SAM)

1995 • 3 citations