Chronic Blockade of Melanocortin Receptors Alleviates Allodynia in Rats with Neuropathic Pain

Ethical guidelines for investigations of experimental pain in conscious animals

1983 • 7,639 citations

Quantitative assessment of tactile allodynia in the rat paw

1994 • 6,953 citations

A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man

1988 • 5,129 citations

Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain.

1994 • 1,059 citations

Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain

1994 • 703 citations

Brainstem Application of Melanocortin Receptor Ligands Produces Long-Lasting Effects on Feeding and Body Weight

1998 • 279 citations

Obesity, Diabetes and Functions for Proopiomelanocortin-derived Peptides

1997 • 152 citations

Receptor Biology of the Melanocortins, a Family of Neuroimmunomodulatory Peptides

1996 • 142 citations

Cancer pain relief using chronic morphine infusion

1984 • 129 citations

Antagonism of the Melanocortin System Reduces Cold and Mechanical Allodynia in Mononeuropathic Rats

2000 • 86 citations

Tizanidine in the Management of Trigeminal Neuralgia

1986 • 85 citations

A time course analysis of the changes in spontaneous and evoked behaviour in a rat model of neuropathic pain

1992 • 84 citations

Intrathecal Morphine Pump as a Treatment Option in Chronic Pain of Nonmalignant Origin

1998 • 83 citations

ACTH-like peptides and morphine: interaction at the level of the CNS

1977 • 81 citations

A clinical and experimental investigation of the effects of tizanidine in trigeminal neuralgia

1993 • 77 citations

Expression of melanocortin receptors and pro-opiomelanocortin in the rat spinal cord in relation to neurotrophic effects of melanocortins

1999 • 74 citations

Intraventricular administration of MSH induces hyperalgesia in rats

1981 • 72 citations

Immunocytochemical localization of pro-opiomelanocortin-derived peptides in the adult rat spinal cord

1986 • 72 citations

Strain differences in adrenergic sensitivity of neuropathic pain behaviors in an experimental rat model

1997 • 58 citations

Functional Recovery After Central Infusion of α-Melanocyte-Stimulating Hormone in Rats With Spinal Cord Contusion Injury

1999 • 50 citations

A comparison of intrathecally administered narcotic and nonnarcotic analgesics for experimental chronic neuropathic pain

1995 • 45 citations

Influence of centrally administered peptides on ear withdrawal from heat in the rabbit

1986 • 33 citations

Analgesic Action of Acute and Chronic Intraspinally Administered Opiate and α<sub>2</sub>-Adrenergic Agonists in Chronic Neuropathic Pain

1994 • 32 citations

Genetic factors influence the development of mechanical hypersensitivity, motor deficits and morphological damage after transient spinal cord ischemia in the rat

1993 • 29 citations

Comparison of tizanidine and morphine with regard to tolerance-developing ability to antinociceptive action

1986 • 12 citations

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1998 • 11 citations

The race to control pain: more participants, more targets

1999 • 9 citations

Synthesis of cyclic α-MSH peptides

1998 • 8 citations