THE ROLE OF INTERLEUKIN 6 IN INTERFERON-γ PRODUCTION IN THERMALLY INJURED MICE

Major Injury Leads to Predominance of the T Helper-2 Lymphocyte Phenotype and Diminished Interleukin-12 Production Associated with Decreased Resistance to Infection

1995 • 503 citations

Effects of natural and recombinant IL 2 on regulation of IFN gamma production and natural killer activity: lack of involvement of the Tac antigen for these immunoregulatory effects.

1984 • 310 citations

THE EFFECTS OF INJURY ON THE ADAPTIVE IMMUNE RESPONSE

1999 • 306 citations

Update on the Mechanisms of Immune Suppression of Injury and Immune Modulation

1996 • 297 citations

Alteration of Monocyte Function Following Major Injury

1988 • 250 citations

Changes in Lymphocyte Activity after Thermal Injury

1979 • 200 citations

PLASMA CYTOKINES FOLLOWING THERMAL INJURY AND THEIR RELATIONSHIP WITH PATIENT MORTALITY, BURN SIZE, AND TIME POSTBURN

1993 • 198 citations

Effects of acute ethanol exposure on cellular immune responses in a murine model of thermal injury

1997 • 152 citations

T-cell reactivity and its predictive role in immunosuppression after burns

1999 • 151 citations

Immunosuppression following thermal injury: the pathogenesis of immunodysfunction

1997 • 130 citations

Alterations of the Immune Response Following Severe Thermal Injury

1966 • 122 citations

Mechanisms of Altered Monocyte Prostaglandin E2 Production in Severely Injured Patients

1988 • 122 citations

Interleukin 6—A Potential Mediator of Lethal Sepsis After Major Thermal Trauma: Evidence for Increased IL-6 Production by Peripheral Blood Mononuclear Cells

1991 • 120 citations

The diagnosis and treatment of infection in the burn patient

1984 • 113 citations

Depressed Immune Response in Burn Patients

1982 • 94 citations

Anti-interleukin-10 antibody restores burn-induced defects in T-cell function

1997 • 94 citations

Modulation of Macrophage Hyperactivity Improves Survival in a Burn-Sepsis Model

1992 • 93 citations

Mechanism of Immunologic Suppression in Burn Injury

1990 • 90 citations

Interleukin-2 and interleukin-6 in relation to burn wound size in the acute phase of thermal injury.

1994 • 89 citations

ACUTE ETHANOL EXPOSURE PRIOR TO THERMAL INJURY RESULTS IN DECREASED T-CELL RESPONSES MEDIATED IN PART BY INCREASED PRODUCTION OF IL-6

1998 • 86 citations

Postburn immunosuppression in an animal model: monocyte dysfunction induced by burned tissue.

1983 • 82 citations

Gender difference in cell-mediated immunity after thermal injury is mediated, in part, by elevated levels of interleukin-6

2000 • 82 citations

Thermal injury-induced immunosuppression in mice: the role of macrophage-derived reactive nitrogen intermediates

1998 • 79 citations

A Review of the Complications of Burns, Their Origin and Importance for Illness and Death

1979 • 74 citations

THERMAL INJURY

1999 • 71 citations

The 1994 Lindberg Award. The production of tumor necrosis factor, interleukin-1, interleukin-6, and prostaglandin E2 by isolated enterocytes and gut macrophages: effect of lipopolysaccharide and thermal injury.

1994 • 68 citations

Role of IL-6 in activation of T cells for acquired cellular resistance to Listeria monocytogenes.

1994 • 67 citations

A Role for Interleukin-6 in Host Defense against MurineChlamydia trachomatisInfection

1998 • 64 citations

What are the Immunological Alterations Induced by Burn Injury?

1984 • 63 citations

Alterations of interferon production in a mouse model of thermal injury.

1982 • 61 citations

Inhibitory Effects of Interleukin 6 on Immunity

1992 • 59 citations

Mechanism for the suppression of gamma-interferon responsiveness in mice after thermal injury.

1982 • 55 citations

THE 1994 LINDBERG AWARD

1994 • 53 citations

Natural killer cell defects resulting from thermal injury

1984 • 48 citations

MARROW GRANULOCYTE-MACROPHAGE PROGENITOR CELL RESPONSE TO BURN INJURY AS MODIFIED BY ENDOTOXIN AND INDOMETHACIN

1994 • 48 citations

Effects of Antimurine Interleukin-6 on Bacterial Translocation During Gut-Derived Sepsis

1994 • 48 citations

Glucocorticoids protect against suppression of T cell responses in a murine model of acute ethanol exposure and thermal injury by regulating IL-6

1998 • 46 citations

Elevated monocyte interleukin-6 (IL-6) production in immunosuppressed trauma patients. I. Role of Fc?RI cross-linking stimulation

1991 • 38 citations

Postburn Immune Suppression

1990 • 29 citations

Effects of Rat Interleukin-2 and Rat Interferon on the Natural Killer Cell Activity of Rat Spleen Cells After Thermal Injury

1992 • 12 citations

Effect of Isoprinosine on Lymphocyte Proliferation and Natural Killer Cell Activity Following Thermal Injury

1989 • 8 citations

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