Occurrence of TEL-AML1 fusion resulting from (12;21) translocation in human early B-lineage leukemia cell lines
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Abstract
References (28)
Fusion of PDGF receptor β to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation
1994 • 1,211 citations
Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia.
1995 • 738 citations
TEL/AML1 fusion resulting from a cryptic t(12;21) is the most common genetic lesion in pediatric ALL and defines a subgroup of patients with an excellent prognosis.
1995 • 566 citations
The t(12;21) of acute lymphoblastic leukemia results in a tel-AML1 gene fusion
1995 • 563 citations
High frequency of t(12;21) in childhood B-lineage acute lymphoblastic leukemia
1995 • 454 citations
TEL/AML-1 dimerizes and is associated with a favorable outcome in childhood acute lymphoblastic leukemia
1996 • 306 citations
The novel activation of ABL by fusion to an ets-related gene, TEL.
1995 • 289 citations
The 12;21 translocation involving TEL and deletion of the other TEL allele: two frequently associated alterations found in childhood acute lymphoblastic leukemia
1996 • 258 citations
Translocation (12;22) (p13;q11) in myeloproliferative disorders results in fusion of the ETS-like TEL gene on 12p13 to the MN1 gene on 22q11.
1995 • 235 citations
t( 12;21): A new recurrent translocation in acute lymphoblastic leukemia
1994 • 229 citations
Frequent loss of heterozygosity at the TEL gene locus in acute lymphoblastic leukemia of childhood
1995 • 132 citations
Genomic organization of TEL: the human ETS-variant gene 6.
1996 • 114 citations
TEL gene is involved in myelodysplastic syndromes with either the typical t(5;12)(q33;p13) translocation or its variant t(10;12)(q24;p13)
1995 • 112 citations
TEL and KIP1 define the smallest region of deletions on 12p13 in hematopoietic malignancies
1995 • 103 citations
Detection and quantification of TEL/AML1 fusion transcripts by polymerase chain reaction in childhood acute lymphoblastic leukemia.
1996 • 101 citations
Fluorescence in situ hybridization mapping of translocations and deletions involving the short arm of human chromosome 12 in malignant hematologic diseases
1994 • 90 citations
TEL-AML1 fusion RNA as a new target to detect minimal residual disease in pediatric B-cell precursor acute lymphoblastic leukemia
1996 • 86 citations
Recurrent chromosomal translocations and fusion genes in leukemia-lymphoma cell lines.
1995 • 85 citations
High incidence of TEL/AML1 fusion resulting from a cryptic t(12;21) in childhood B-lineage acute lymphoblastic leukemia in Taiwan.
1996 • 83 citations
TEL/AML1 fusion gene is a rare event in adult acute lymphoblastic leukemia.
1996 • 76 citations
Mutational analysis of the candidate tumor suppressor genes TEL and KIP1 in childhood acute lymphoblastic leukemia.
1996 • 67 citations
Acute lymphoblastic leukemia of childhood: identification of two distinct regions of deletion on the short arm of chromosome 12 in the region of TEL and KIP1
1996 • 57 citations
The der(21)t(12;21) chromosome is always formed in a 12;21 translocation associated with childhood acute lymphoblastic leukaemia
1996 • 54 citations
The TEL gene and human leukemia
1996 • 54 citations
Identification of cytogenetically undetected 12p13 translocations and associated deletions with fluorescence in situ hybridization
1995 • 42 citations
Lack of TEL-AML1 fusion transcript resulting from a cryptic t(12;21) in adult B lineage acute lymphoblastic leukemia in Taiwan.
1996 • 25 citations
Epidemiological research on the influence of maternal and paternal external exposure factors on the incidence of congenital leukaemia
1996 • 2 citations
Deleted Work
1955 • 0 citations