A20 inhibits NF-κB activation by dual ubiquitin-editing functions

Induction of TNF Receptor I-Mediated Apoptosis via Two Sequential Signaling Complexes

2003 • 2,545 citations

Activation of the IκB Kinase Complex by TRAF6 Requires a Dimeric Ubiquitin-Conjugating Enzyme Complex and a Unique Polyubiquitin Chain

2000 • 1,801 citations

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling

2004 • 1,759 citations

Failure to Regulate TNF-Induced NF-κB and Cell Death Responses in A20-Deficient Mice

2000 • 1,374 citations

The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

2004 • 1,063 citations

The tumour suppressor CYLD negatively regulates NF-κB signalling by deubiquitination

2003 • 983 citations

The signaling adaptors and pathways activated by TNF superfamily

2003 • 481 citations

Recruitment of the IKK Signalosome to the p55 TNF Receptor

2000 • 457 citations

The novel functions of ubiquitination in signaling

2004 • 455 citations

Recruitment of TNF Receptor 1 to Lipid Rafts Is Essential for TNFα-Mediated NF-κB Activation

2003 • 441 citations

The A20 cDNA induced by tumor necrosis factor alpha encodes a novel type of zinc finger protein.

1990 • 417 citations

The tumor necrosis factor-inducible zinc finger protein A20 interacts with TRAF1/TRAF2 and inhibits NF-kappaB activation.

1996 • 414 citations

Ubiquitin-proteasome system

2004 • 308 citations

A20 and A20-binding proteins as cellular inhibitors of nuclear factor-κB-dependent gene expression and apoptosis

2000 • 303 citations

The Zinc Finger Protein A20 Inhibits TNF-induced NF-κB–dependent Gene Expression by Interfering with an RIP- or TRAF2-mediated Transactivation Signal and Directly Binds to a Novel NF-κB–inhibiting Protein ABIN

1999 • 289 citations

A novel superfamily of predicted cysteine proteases from eukaryotes, viruses and Chlamydia pneumoniae

2000 • 273 citations

Otubains: a new family of cysteine proteases in the ubiquitin pathway

2003 • 258 citations

The Kinase Activity of Rip1 Is Not Required for Tumor Necrosis Factor-α-induced IκB Kinase or p38 MAP Kinase Activation or for the Ubiquitination of Rip1 by Traf2

2004 • 251 citations

Zinc-finger protein A20, a regulator of inflammation and cell survival, has de-ubiquitinating activity

2004 • 220 citations

Deubiquitinating enzymes—the importance of driving in reverse along the ubiquitin–proteasome pathway

2003 • 189 citations

The cytokine‐inducible zinc finger protein A20 inhibits IL‐1‐induced NF‐κB activation at the level of TRAF6

1999 • 175 citations

A Novel Type of Deubiquitinating Enzyme

2003 • 161 citations

Nuclear Factor kB-independent Cytoprotective Pathways Originating at Tumor Necrosis Factor Receptor-associated Factor 2

1998 • 104 citations

Identification of a Novel A20-binding Inhibitor of Nuclear Factor-κB Activation Termed ABIN-2

2001 • 97 citations

Human disorders of ubiquitination and proteasomal degradation

2004 • 92 citations

Functional redundancy of the zinc fingers of A20 for inhibition of NF‐κB activation and protein–protein interactions

2001 • 69 citations