[3H]AF-DX 116 labels subsets of muscarinic cholinergic receptors in rat brain and heart

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Muscarinic Cholinergic Binding in Rat Brain

1974 • 1,214 citations

Primary Structure and Biochemical Properties of an M ₂ Muscarinic Receptor

1987 • 510 citations

Binding profile of a novel cardioselective muscarine receptor antagonist, AF-DX 116, to membranes of peripheral tissues and brain in the rat

1986 • 373 citations

Primary structure of porcine cardiac muscarinic acetylcholine receptor deduced from the cDNA sequence

1986 • 344 citations

Cardiac muscarinic cholinergic receptors. Biochemical identification and characterization.

1978 • 314 citations

Autoradiographic localization of M1 and M2 muscarine receptors in the rat brain

1986 • 312 citations

Cardioselective profile of AF-DX 116, a muscarine M2 receptor antagonist

1986 • 283 citations

[3H] pirenzepine selectively identifies a high affinity population of muscarinic cholinergic receptors in the rat cerebral cortex

1982 • 184 citations

Muscarinic antagonist binding site heterogeneity as evidenced by autoradiography after direct labeling with [3H]-QNB and [3H]-pirenzepine

1984 • 148 citations

[3H]pirenzepine and (-)-[3H]quinuclidinyl benzilate binding to rat cerebral cortical and cardiac muscarinic cholinergic sites. I. Characterization and regulation of agonist binding to putative muscarinic subtypes.

1986 • 129 citations

Distribution of muscarinic receptor subtypes in rat brain as determined in binding studies with AF-DX 116 and pirenzepine

1987 • 119 citations

A cholinergic antagonist identifies a subclass of muscarinic receptors in isolated rat pancreatic acini.

1987 • 51 citations

Pharmacological differences between the high-affinity muscarinic agonist binding states of the rat heart and cerebral cortex labeled with (+)-[3H]cismethyldioxolane.

1984 • 50 citations

AF-DX 116 discriminates between muscarinic M2 receptors of the heart and vasculature

1987 • 33 citations

Heterogeneity of the M1 muscarinic receptor subtype between peripheral lung and cerebral cortex demonstrated by the selective antagonist AF-DX 116

1987 • 26 citations