The cloning and expression of the aroL gene from Escherichia coli K12. Purification and complete amino acid sequence of shikimate kinase II, the aroL-gene product

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

The Reliability of Molecular Weight Determinations by Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis

1969 • 20,498 citations

Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold.

1982 • 5,284 citations

A rapid boiling method for the preparation of bacterial plasmids

1981 • 3,334 citations

Empirical Predictions of Protein Conformation

1978 • 3,167 citations

A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments

1982 • 3,041 citations

A system for shotgun DNA sequencing

1981 • 2,710 citations

Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination.

1983 • 2,456 citations

Compilation and analysis ofEscherichia colipromoter DNA sequences

1983 • 2,228 citations

Prolonged incubation in calcium chloride improves the competence of Escherichia coli cells

1979 • 1,454 citations

Determinant of cistron specificity in bacterial ribosomes

1975 • 1,363 citations

Linkage map of Escherichia coli K-12, edition 7

1983 • 1,250 citations

Evidence for two functional gal promoters in intact Escherichia coli cells.

1981 • 1,022 citations

Trans-complementable copy-number mutants of plasmid ColE1

1980 • 975 citations

A mew computer method for the storage and manipulation of DNA gel reading data

1980 • 679 citations

Computer methods to locate signals in nucleic acid sequences

1984 • 673 citations

[16] Plasmids of Escherichia coli as cloning vectors

1979 • 655 citations

Amino acids : biosynthesis and genetic regulation

1983 • 333 citations

Substrate positions and induced-fit in crystalline adenylate kinase

1977 • 304 citations

Pathways of biosynthesis of aromatic amino acids and vitamins and their control in microorganisms.

1968 • 187 citations

The subunit structure of the arom multienzyme complex of Neurospora crassa. A possible pentafunctional polypeptide chain

1977 • 133 citations

Organization of Enzymes in the Polyaromatic Synthetic Pathway: Separability in Bacteria

1969 • 101 citations

A cluster-gene: Evidence for one gene, one polypeptide, five enzymes

1977 • 98 citations

Homologies between different procaryotic DNA-binding regulatory proteins and between their sites of action.

1982 • 98 citations

The nucleotde sequence of therhogene ofE. coliK-12

1983 • 93 citations

The nucleotide sequence of theEscherichta coli fusgene, coding for elongation factor G

1984 • 88 citations

The nucleotide sequence of theuvrDgene ofE. coli

1984 • 87 citations

Nucleotide sequence of dnaB and the primary structure of the dnaB protein from Escherichia coli.

1984 • 77 citations

Escherichia coliΔ¹-pyrroline-5-carboxylate reductase: gene sequence, protein overproduction and purification

1982 • 75 citations

T4 polynucleotide kinase; cloning of the gene (pseT) and amplification of its product.

1985 • 71 citations

The purification of 5‐enolpyruvylshikimate 3‐phosphate synthase from an overproducing strain of Escherichia coli

1984 • 68 citations

Aromatic amino acid biosynthesis: regulation of shikimate kinase in Escherichia coli K-12

1979 • 65 citations

The 3-dehydroquinate synthase activity of the pentafunctional arom enzyme complex of Neurospora crassa is Zn2+-dependent

1985 • 64 citations

Dehydroquinate synthetase from Escherichia coli: purification, cloning, and construction of overproducers of the enzyme

1984 • 60 citations

The purification of shikimate dehydrogenase from Escherichia coli

1985 • 57 citations

Cloning and expression in Escherichia coli K-12 of the biosynthetic dehydroquinase function of the arom cluster gene from the eucaryote, Aspergillus nidulans

1982 • 56 citations

Purification of 5-enolpyruvylshikimate 3-phosphate synthase from Escherichia coli

1983 • 52 citations

Inhibition of 3-Deoxy- <scp>d</scp> -Arabinoheptulosonic Acid-7-Phosphate Synthetase (trp) in Escherichia coli

1969 • 47 citations

Operator mutations of the Escherichia coli aroF gene.

1985 • 40 citations

Isolation of a bifunctional domain from the pentafunctional arom enzyme complex of Neurospora crassa

1983 • 39 citations

The subunit structure of the arom multienzyme complex of Neurospora crassa. Evidence from peptide ‘maps’ for the identity of the subunits

1978 • 35 citations

Primary structure of bovine complement activation fragment C4a, the third anaphylatoxin. Purification and complete amino acid sequence

1982 • 33 citations

Regulation of Aromatic Amino Acid Biosynthesis in Bacillus subtilis 168

1972 • 32 citations

Purification and characterization of shikimate kinase enzyme activity in Bacillus subtilis.

1975 • 30 citations

Analysis of the structure and transcription of the aro3 cluster gene in Schizosaccharomyces pombe

1984 • 26 citations

Genetic and molecular analysis of aroL, the gene for shikimate kinase II in Escherichia coli K-12

1986 • 26 citations

The serine proteinase chain of human complement component C̅1s. Cyanogen bromide cleavage and N-terminal sequences of the fragments

1983 • 26 citations

Aggregation und Trennbarkeit der Enzyme des Shikimat-Pathway bei Hefen

1981 • 25 citations

The biosynthesis of aromatic compounds

1981 • 22 citations

The genetic fine structure of the complex locus aro3 involved in early aromatic amino acid biosynthesis in Schizosaccharomyces pombe

1979 • 22 citations

Isolation of the AROl Cluster Gene of Saccharomyces cerevisiae

1983 • 21 citations

Shikimate Kinase Isoenzymes in Salmonella typhimurium

1968 • 18 citations

Regulated Enzymes of Aromatic Amino Acid Synthesis: Control, Isozymic Nature, and Aggregation in Bacillus subtilis and Bacillus licheniformis

1969 • 17 citations