Roles of Airway Epithelial Integrins in Health and Disease

Adhesion between epithelial cells and T lymphocytes mediated by E-cadherin and the αEβ7 integrin

1994 • 1,131 citations

Crystal structure of the A domain from the a subunit of integrin CR3 (CD11 b/CD18)

1995 • 893 citations

Cell adhesion events mediated by α4 integrins are essential in placental and cardiac development

1995 • 792 citations

Embryonic mesodermal defects in α5 integrin-deficient mice

1993 • 694 citations

Expression of the β6 integrin subunit in development, neoplasia and tissue repair suggests a role in epithelial remodeling

1995 • 470 citations

Protein sequence of endothelial glycoprotein IIIa derived from a cDNA clone. Identity with platelet glycoprotein IIIa and similarity to “integrin”.

1987 • 466 citations

The primary structure of the VLA-2/collagen receptor alpha 2 subunit (platelet GPIa): homology to other integrins and the presence of a possible collagen-binding domain.

1989 • 343 citations

Epithelial integrin alpha 6 beta 4: complete primary structure of alpha 6 and variant forms of beta 4.

1990 • 323 citations

A novel integrin (alpha E beta 4) from human epithelial cells suggests a fourth family of integrin adhesion receptors.

1989 • 314 citations

Characterization of the integrin alpha v beta 6 as a fibronectin-binding protein.

1992 • 292 citations

Primary structure of the leukocyte function-associated molecule-1 alpha subunit: an integrin with an embedded domain defining a protein superfamily.

1989 • 285 citations

The human leukocyte adhesion glycoprotein Mac-1 (complement receptor type 3, CD11b) alpha subunit. Cloning, primary structure, and relation to the integrins, von Willebrand factor and factor B.

1988 • 281 citations

Cloning and sequence analysis of beta-4 cDNA: an integrin subunit that contains a unique 118 kd cytoplasmic domain.

1990 • 278 citations

cDNA cloning and complete primary structure of the alpha subunit of a leukocyte adhesion glycoprotein, p150,95.

1987 • 277 citations

Electron microscopy and structural model of human fibronectin receptor.

1988 • 265 citations

The primary structure of the alpha 4 subunit of VLA-4: homology to other integrins and a possible cell-cell adhesion function.

1989 • 264 citations

Role of the integrin alpha v beta 6 in cell attachment to fibronectin. Heterologous expression of intact and secreted forms of the receptor.

1994 • 250 citations

Amino acid sequence of a novel integrin beta 4 subunit and primary expression of the mRNA in epithelial cells.

1990 • 249 citations

Multiple integrins mediate cell attachment to cytotactin/tenascin.

1993 • 248 citations

Restricted distribution of integrin beta 6 mRNA in primate epithelial tissues.

1993 • 240 citations

H36-alpha 7 is a novel integrin alpha chain that is developmentally regulated during skeletal myogenesis [published erratum appears in J Cell Biol 1992 Jul;118(1):213]

1992 • 236 citations

Sequence and tissue distribution of the integrin alpha 9 subunit, a novel partner of beta 1 that is widely distributed in epithelia and muscle [published erratum appears in J Cell Biol 1994 Feb;124(3):395]

1993 • 221 citations

A new surface antigen on intraepithelial lymphocytes in the intestine

1990 • 216 citations

A novel member of the integrin receptor family mediates Arg-Gly-Asp-stimulated neutrophil phagocytosis.

1989 • 206 citations

The integrin alpha 9 beta 1 mediates cell attachment to a non-RGD site in the third fibronectin type III repeat of tenascin.

1994 • 200 citations

Complete amino acid sequence of a novel integrin beta subunit (beta 6) identified in epithelial cells using the polymerase chain reaction.

1990 • 195 citations

Molecular cloning of the rat integrin alpha 1-subunit: a receptor for laminin and collagen.

1990 • 191 citations

Cloning and expression of a divergent integrin subunit beta 8.

1991 • 179 citations

Cloning, primary structure and properties of a novel human integrin beta subunit.

1990 • 170 citations

The alpha v beta 6 integrin promotes proliferation of colon carcinoma cells through a unique region of the beta 6 cytoplasmic domain.

1994 • 165 citations

Distribution of Integrin Cell Adhesion Receptors in Normal and Malignant Lung Tissue

1992 • 163 citations

Characterization of the integrin alpha 8 subunit: a new integrin beta 1-associated subunit, which is prominently expressed on axons and on cells in contact with basal laminae in chick embryos.

1991 • 161 citations

Complete amino acid sequence of an integrin beta subunit (beta 7) identified in leukocytes

1991 • 124 citations

Expression of native and truncated forms of the human integrin alpha 1 subunit.

1993 • 108 citations

Distribution of Integrin Cell Adhesion Receptors on Normal Bronchial Epithelial Cells and Lung Cancer Cells In Vitro and In Vivo

1993 • 92 citations

Biochemical evidence for a homophilic interaction of the alpha 3 beta 1 integrin.

1993 • 84 citations

Distribution of integrins alpha v beta 6 and alpha 9 beta 1 and their known ligands, fibronectin and tenascin, in human airways.

1995 • 73 citations

Purification of two smooth muscle glycoproteins related to integrin. Distribution in cultured chicken embryo fibroblasts.

1987 • 65 citations

Characterization through cDNA cloning of galactoprotein b3 (Gap b3), a cell surface membrane glycoprotein showing enhanced expression on oncogenic transformation. Identification of Gap b3 as a member of the integrin superfamily.

1990 • 55 citations

[20] Polymerase chain reaction cloning with degenerate primers: Homology-based identification of adhesion molecules

1994 • 38 citations

Identity between the novel integrin β7 subunit and an antigen found highly expressed on intraepithelial lymphocytes in the small intestine

1991 • 37 citations

Analysis of rodent platelet glycoprotein IIb: evidence for evolutionarily conserved domains and alternative proteolytic processing

1990 • 37 citations

Novel Integrin α and β Subunit cDNAs Identified in Airway Epithelial Cells and Lung Leukocytes Using the Polymerase Chain Reaction

1991 • 37 citations

Molecular cloning of the alpha subunit of human and guinea pig leukocyte adhesion glycoprotein Mo1: chromosomal localization and homology to the alpha subunits of integrins.

1988 • 33 citations