Biochemical Control of Melanogenesis and Melanosomal Organization

The Metabolic and Molecular Bases of Inherited Disease

1995 • 12,086 citations

Melanins and Melanogenesis

1992 • 602 citations

Photoprotection by melanin—a comparison of black and Caucasian skin

1979 • 446 citations

The genetics of pigmentation: from fancy genes to complex traits

1996 • 360 citations

Mechanisms of Ultraviolet Light‐Induced Pigmentation

1996 • 349 citations

Regulation of Cre recombinase activity by the synthetic steroid RU 486

1996 • 276 citations

Melanosomes Are Specialized Members of the Lysosomal Lineage of Organelles

1995 • 270 citations

Melanocortin 1 Receptor Variants in an Irish Population

1998 • 252 citations

Supranuclear Melanin Caps Reduce Ultraviolet Induced DNA Photoproducts in Human Epidermis

1998 • 237 citations

Keratins and skin disorders

2004 • 225 citations

Clinical and Pathological Features of Pachyonychia Congenita

2005 • 202 citations

5,6-Dihydroxyindole is a melanin precursor showing potent cytotoxicity

1978 • 187 citations

Modulation of melanogenic protein expression during the switch from eu-to pheomelanogenesis

1995 • 177 citations

Molecular events in melanoma development and progression

1998 • 152 citations

Delayed Wound Healing in Keratin 6a Knockout Mice

2000 • 151 citations

Accumulation of drugs on melanin.

1973 • 149 citations

An Inducible Mouse Model for Epidermolysis Bullosa Simplex

2001 • 145 citations

Keratin 17 null mice exhibit age- and strain-dependent alopecia

2002 • 122 citations

Ultraviolet B and Melanocyte-Stimulating Hormone (MSH) Stimulate mRNA Production for ∝MSH Receptors and Proopiomelanocortin-Derived Peptides in Mouse Melanoma Cells and Transformed Keratinocytes

1995 • 118 citations

Keratinocytes and Fibroblasts in a Human Skin Equivalent Model Enhance Melanocyte Survival and Melanin Synthesis After Ultraviolet Irradiation

1995 • 116 citations

The Genetic Basis of Pachyonychia Congenita

2005 • 105 citations

Discovery of a novel murine keratin 6 (K6) isoform explains the absence of hair and nail defects in mice deficient for K6a and K6b

2001 • 103 citations

Visual anomalies associated with albinism

1990 • 102 citations

Introducing a Null Mutation in the Mouse K6α and K6β Genes Reveals Their Essential Structural Role in the Oral Mucosa

2000 • 102 citations

Genetic Disorders of Pigmentation

1994 • 99 citations

Modulation of murine melanocyte function invitro by agouti signal protein

1997 • 96 citations

Genetics, Development, and Malignancy of Melanocytes

1993 • 89 citations

HLA-Independent Heterogeneity of CD8+ T Cell Responses to MAGE-3, Melan-A/MART-1, gp100, Tyrosinase, MC1R, and TRP-2 in Vaccine-Treated Melanoma Patients

1998 • 86 citations

DUAL ROLE OF MELANINS AND MELANIN PRECURSORS AS PHOTOPROTECTIVE AND PHOTOTOXIC AGENTS: INHIBITION OF ULTRAVIOLET RADIATION‐INDUCED LIPID PEROXIDATION

1995 • 86 citations

Hair melanins and hair color: Ultrastructural and biochemical aspects

1993 • 86 citations

THE CYTOTOXICITY OF MELANIN PRECURSORS*

1963 • 83 citations

Abnormalities of the Central Visual Pathways in Prader–Willi Syndrome Associated with Hypopigmentation

1986 • 80 citations

Focal Activation of a Mutant Allele Defines the Role of Stem Cells in Mosaic Skin Disorders

2001 • 73 citations

Characterization of genes modulated during pheomelanogenesis using differential display

1998 • 72 citations

Melanosomal proteins as melanoma-specific immune targets

1997 • 58 citations

Cysteine Transport in Melanosomes from Murine Melanocytes

1999 • 55 citations

Characterization of an inducible, epidermal-specific knockout system: differential expression of lacZ in different Cre reporter mouse strains.

2000 • 51 citations

Sunlight, melanogenesis and radicals in the skin

1988 • 45 citations

Characterization of an inducible, epidermal-specific knockout system: Differential expression oflacZ in different Cre reporter mouse strains

2000 • 44 citations

A transgenic mouse model with an inducible skin blistering disease phenotype

1996 • 40 citations

Changes in expression of putative antigens encoded by pigment genes in mouse melanomas at different stages of malignant progression.

1995 • 40 citations

In utero activation of K5.CrePR1 induces gene deletion

2002 • 36 citations

Gene Therapy for Autosomal Dominant Disorders of Keratin

2005 • 35 citations

Comparative Action Spectrum for Ultraviolet Light Killing of Mouse Melanocytes from Different Genetic Coat Color Backgrounds

1997 • 33 citations

Colour genes, oncogenes and melanocyte differentiation

1991 • 32 citations

Expression of MK6a dominant-negative and C-terminal mutant transgenes in mice has distinct phenotypic consequences in the epidermis and hair follicle

1999 • 31 citations

A Novel Mouse Type I Intermediate Filament Gene, Keratin 17n (K17n), Exhibits Preferred Expression in Nail Tissue

2004 • 31 citations

Visual and auditory anomalies in Chediak-Higashi syndrome

1983 • 24 citations

Effects of Ultraviolet Irradiation on the Cell Cycle

1994 • 19 citations

Identification of sporadic mutations in the helix initiation motif of keratin 6 in two pachyonychia congenita patients: further evidence for a mutational hot spot

1999 • 19 citations

Cellular pathways leading to melanoma differentiation: therapeutic implications

1994 • 14 citations

II. Melanins, melanogenesis and skin photoprotection

1994 • 10 citations