Transcriptional regulation of two cytotoxk T lymphocyte-specific serine protease gene

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing

1980 • 3,476 citations

Cyclic AMP and the induction of eukaryotic gene transcription.

1988 • 1,041 citations

Identification of a Putative Regulator of Early T Cell Activation Genes

1988 • 933 citations

Modulation of Inflammation and Immunity by Cyclic AMP

1974 • 923 citations

Active chromatin

1982 • 549 citations

The chemistry and biology of unusual DNA structures adopted by oligopurine · oligopyrimidine sequences

1988 • 543 citations

Induction of Interleukin 2 Messenger RNA Inhibited by Cyclosporin A

1984 • 404 citations

Sequential expression of genes involved in human T lymphocyte growth and differentiation.

1985 • 291 citations

Regulation of human interleukin-2 gene: Functional DNA sequences in the 5′ flanking region for the gene expression in activated T lymphocytes

1986 • 288 citations

Comparison of Total Sequence of a Cloned Rabbit β-Globin Gene and Its Flanking Regions with a Homologous Mouse Sequence

1979 • 256 citations

Novel Serine Proteases Encoded by Two Cytotoxic T Lymphocyte-Specific Genes

1986 • 246 citations

T‐Lymphocyte Activation: The Role of Protein Kinase C and the Bifurcating Inositol Phospholipid Signal Transduction Pathway

1987 • 203 citations

High-affinity receptor-mediated internalization and degradation of interleukin 2 in human T cells.

1986 • 192 citations

A 275 basepair fragment at the 5' end of the interleukin 2 gene enhances expression from a heterologous promoter in response to signals from the T cell antigen receptor.

1987 • 174 citations

Promoter region of interleukin-2 gene undergoes chromatin structure changes and confers inducibility on chloramphenicol acetyltransferase gene during activation of T cells.

1986 • 171 citations

Increase in cytosolic free calcium concentration is an intracellular messenger for the production of interleukin 2 but not for expression of the interleukin 2 receptor.

1985 • 164 citations

Localization of DNA sequences necessary for transcription of the rabbit β-globin gene in vitro

1981 • 158 citations

Transmembrane Ion Fluxes during Activation of Human T Lymphocytes: Role of Ca²⁺, Na⁺/H⁺ Exchange and Phospholipid Turnover

1987 • 154 citations

Calcium protects DNase I from proteinase K: A new method for the removal of contaminating RNase from DNase I

1980 • 149 citations

A high proportion of T lymphocytes that infiltrate H-2-incompatible heart allografts in vivo express genes encoding cytotoxic cell-specific serine proteases, but do not express the MEL-14-defined lymph node homing receptor.

1988 • 130 citations

Interleukin 2-induced lymphocyte proliferation is independent of increases in cytosolic-free calcium concentrations.

1985 • 113 citations

Cloning of two genes that are specifically expressed in activated cytotoxic T lymphocytes.

1986 • 91 citations

Induction, suppression and superinduction of lymphokine mRNA in T lymphocytes

1987 • 82 citations

A conserved sequence in the T-cell receptor beta-chain promoter region.

1988 • 74 citations

Promoter Region of Interleukin-2 Gene Undergoes Chromatin Structure Changes and Confers Inducibility on Chloramphenicol Acetyltransferase Gene During Activation of T Cells

1986 • 67 citations

Molecular mechanisms involved in T cell activation. II. The phosphatidylinositol signal-transducing mechanism mediates antigen-induced lymphokine production but not interleukin 2-induced proliferation in cloned cytotoxic T lymphocytes.

1987 • 67 citations

Cellular and molecular properties of an antigen-specific cytotoxic T lymphocyte line.

1982 • 50 citations

T3 delta pre-mRNA is transcribed from a non-TATA promoter and is alternatively spliced in human T cells.

1986 • 46 citations

Chromatin structure, DNA structure

1982 • 44 citations

Simian virus 40-mediated cis induction of the Xenopus β-globin DNase I hypersensitive site

1985 • 42 citations

A serine protease (CCP1) is sequestered in the cytoplasmic granules of cytotoxic T lymphocytes.

1987 • 41 citations

Organization of two genes encoding cytotoxic T lymphocyte-specific serine proteases CCPI and CCPII

1988 • 39 citations