Inhibition of Plasminogen Activation by Lipoprotein(a)

cDNA sequence of human apolipoprotein(a) is homologous to plasminogen

1987 • 1,842 citations

Kinetics of the activation of plasminogen by human tissue plasminogen activator. Role of fibrin.

1982 • 1,300 citations

A NEW SERUM TYPE SYSTEM IN MAN—THE L_p SYSTEM

1963 • 1,292 citations

Purification and Characterization of TAFI, a Thrombin-activable Fibrinolysis Inhibitor

1995 • 684 citations

Lipoprotein(a), fibrin binding, and plasminogen activation.

1990 • 460 citations

Molecular definition of the extreme size polymorphism in apolipoprotein(a)

1993 • 316 citations

Plasmin catalyzes binding of lipoprotein (a) to immobilized fibrinogen and fibrin.

1989 • 286 citations

Identification of the cysteine residue in apolipoprotein(a) that mediates extracellular coupling with apolipoprotein B-100.

1993 • 206 citations

Rhesus Monkey Apolipoprotein(a)

1989 • 182 citations

The apolipoprotein(a) kringle IV repeats which differ from the major repeat kringle are present in variably-sized isoforms

1993 • 176 citations

Antifibrinolytic activity of apolipoprotein(a) in vivo: Human apolipoprotein(a) transgenic mice are resistant to tissue plasminogen activator-mediated thrombolysis

1995 • 156 citations

Cys4057 of apolipoprotein(a) is essential for lipoprotein(a) assembly.

1993 • 148 citations

Apolipoprotein(a): expression and characterization of a recombinant form of the protein in mammalian cells

1991 • 135 citations

Relation between number of apolipoprotein(a) kringle 4 repeats and mobility of isoforms in agarose gel: basis for a standardized isoform nomenclature

1996 • 127 citations

Inhibition of Fibrinolysis by Lipoprotein(a)

2001 • 122 citations

Lipoprotein(a) inhibition of plasminogen activation by tissue-type plasminogen activator

1990 • 112 citations

Identification of Two Functionally Distinct Lysine-binding Sites in Kringle 37 and in Kringles 32−36 of Human Apolipoprotein(a)

1995 • 97 citations

Purification and characterization of 3 fibrinogens with different molecular weights obtained from normal human plasma

1985 • 96 citations

Tissue-type plasminogen activator binds to and is inhibited by surface-bound lipoprotein(a) and low-density lipoprotein

1991 • 91 citations

The Mechanism of Plasminogen Activation and the Variability of the Fibrin Effector during Tissue‐type Plasminogen Activator—mediated Fibrinolysis

1992 • 88 citations

Lipoprotein(a) Assembly

1996 • 74 citations

Lys-plasminogen is a significant intermediate in the activation of Glu-plasminogen during fibrinolysis in vitro.

1992 • 69 citations

A Steady-state Template Model That Describes the Kinetics of Fibrin-stimulated [Glu1]- and [Lys78]Plasminogen Activation by Native tissue-type Plasminogen Activator and Variants That Lack Either the Finger or Kringle-2 Domain

1997 • 68 citations

Analysis of the Proteolytic Activity of a Recombinant Form of Apolipoprotein(a)

1995 • 66 citations

Antifibrinolytic Effect of Recombinant Apolipoprotein(a) in Vitro Is Primarily Due to Attenuation of tPA-Mediated Glu-Plasminogen Activation

1995 • 63 citations

Primary soluble plasmic degradation product of human crosslinked fibrin. Isolation and stoichiometry of the (DD)E complex

1979 • 62 citations

Sequences within Apolipoprotein(a) Kringle IV Types 6−8 Bind Directly to Low-Density Lipoprotein and Mediate Noncovalent Association of Apolipoprotein(a) with Apolipoprotein B-100

1998 • 58 citations

The Solution Phase Interaction between Apolipoprotein(a) and Plasminogen Inhibits the Binding of Plasminogen to a Plasmin-Modified Fibrinogen Surface

1997 • 54 citations

Apolipoprotein(a) Attenuates Endogenous Fibrinolysis in the Rabbit Jugular Vein Thrombosis Model In Vivo

1997 • 52 citations

Lp(a) Particles Mold Fibrin-Binding Properties of Apo(a) in Size-Dependent Manner

2002 • 48 citations

Comparison of ligand-binding sites of modeled apo[a] kringle-like sequences in human lipoprotein[a].

1993 • 46 citations

A Critical Evaluation of the Role of Lp(a) in Cardiovascular Disease: Can Lp(a) Be Useful in Risk Assessment?

2002 • 44 citations

The course and prerequisites of Lys-plasminogen formation during fibrinolysis

1988 • 41 citations

Lipoprotein(a) in diet-induced atherosclerosis in nonhuman primates.

1991 • 40 citations

Evidence that the fibrinogen binding domain of Apo(a) is outside the lysine binding site of kringle IV-10: a study involving naturally occurring lysine binding defective lipoprotein(a) phenotypes.

1996 • 39 citations

Production and Characterization of Recombinant Human Plasminogen(S741C-Fluorescein)

1997 • 35 citations

Expression and characterization of apolipoprotein(a) kringle IV types 1, 2 and 10 in mammalian cells

1994 • 33 citations

Influence of Lipoprotein (a) Levels and Isoforms on Fibrinolytic Activity – Study in Families with High Lipoprotein (a) Levels

1998 • 33 citations

The Binding Activity of the Macrophage Lipoprotein(a)/Apolipoprotein(a) Receptor Is Induced by Cholesterol via a Post-translational Mechanism and Recognizes Distinct Kringle Domains on Apolipoprotein(a)

1996 • 33 citations

Lipoprotein(a) enhances plasma clot lysis in vitro

1990 • 27 citations

The Extinction Coefficient of Fibrinogen from Man, Dog, Elephant, Sheep, and Goat at 280 m

1970 • 27 citations

Atherosclerosis in a rhesus monkey with genetic hypercholesterolemia and elevated plasma Lp(a)

1993 • 23 citations

A Kinetic Analysis of the Tissue Plasminogen Activator and DSPAα1 Cofactor Activities of Untreated and TAFIa-treated Soluble Fibrin Degradation Products of Varying Size

2001 • 22 citations

Properties of Human Free Apolipoprotein(a) and Lipoprotein(a) after Either Freezing or Lyophilization in the Presence and Absence of Cryopreservatives

2001 • 21 citations

Kinetic analysis of lipoprotein (a) inhibition of plasminogen activation by tissue plasminogen activator in vitro

1991 • 20 citations

Modulation of Fibrin Cofactor Activity in Plasminogen Activation

2001 • 20 citations

The Kringle V-Protease Domain Is a Fibrinogen Binding Region within Apo(a)

2001 • 14 citations

Characterization of the interaction of recombinant apolipoprotein(a) with modified fibrinogen surfaces and fibrin clots

2000 • 12 citations

Characterization of the interaction of recombinant apolipoprotein(a) with modified fibrinogen surfaces and fibrin clots

2000 • 11 citations

Lipoprotein(a): identification of subjects with a superbinding capacity for fibrinogen

1997 • 7 citations

The complete cDNA sequence encoding plasminogen from the European hedgehog (Erinaceus europaeus)

1996 • 7 citations