Permeable support type influences the transport of compounds across Caco-2 cells

Characterization of the Human Colon Carcinoma Cell Line (Caco-2) as a Model System for Intestinal Epithelial Permeability

1989 • 2,127 citations

Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

1991 • 1,787 citations

Enterocyte-like differentiation and polarization of the human colon carcinoma cell line Caco-2 in culture

1983 • 1,765 citations

Epithelial Transport Of Drugs In Cell Culture. I: A Model For Studying The Passive Diffusion Of Drugs Over Intestinal Absorbtive (Caco-2) Cells

1990 • 820 citations

Absence of HeLa Cell Contamination in 169 Cell Lines Derived From Human Tumors2

1977 • 648 citations

Epithelial properties of human colonic carcinoma cell line Caco-2: electrical parameters

1984 • 349 citations

Transport and permeability properties of human Caco-2 cells: An in vitro model of the intestinal epithelial cell barrier

1990 • 234 citations

Epithelial Transport of Drugs in Cell Culture. II: Effect of Extracellular Calcium Concentration on the Paracellular Transport of Drugs of Different Lipophilicities across Monolayers of Intestinal Epithelial (Caco-2) Cells

1990 • 183 citations

Transport of a large neutral amino acid (phenylalanine) in a human intestinal epithelial cell line: Caco-2

1990 • 163 citations

Increases in guinea pig small intestinal transepithelial resistance induced by osmotic loads are accompanied by rapid alterations in absorptive-cell tight-junction structure.

1983 • 163 citations

Transport of bile acids in a human intestinal epithelial cell line, Caco-2

1990 • 136 citations

A specific sorting signal is not required for the polarized secretion of newly synthesized proteins from cultured intestinal epithelial cells.

1988 • 110 citations

The Transport of Vitamin B12 Through Polarized Monolayers of Caco-2 Cells

1990 • 109 citations

A model of human small intestinal absorptive cells. 1. Transport barrier.

1991 • 108 citations

Pharmacology of Intestinal Permeation I

1984 • 60 citations

In vitro drug absorption models. I. Brush border membrane vesicles, isolated mucosal cells and everted intestinal rings: characterization and salicylate accumulation.

1985 • 47 citations

Isolation and characterisation of clones from the Caco-2 cell line displaying increased taurocholic acid transport

1991 • 38 citations

Taurocholate transport by human ileal brush border membrane vesicles

1987 • 32 citations